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Researchers use high-speed atomic force microscopy to explore the binding mechanism of cadherins

Cell, tissue, and organ structure is maintained by cell-cell adhesion molecules that connect opposing cells. Cadherins are a class of essential cell-cell adhesion molecules for tissue formation and integrity, and defects in cadherin function cause various diseases (e.g., cancer invasion).

19 Jul 2022

CN Bio opens new laboratory facilities to extend Organ-on-a-chip contract research services capabilities

State-of-the-art laboratories significantly expand project capacity to meet increasing market demand for Organ-on-a-Chip research services.

From CN Bio 19 Jul 2022

Researchers develop new SERS method for active capture of target molecules

Recently, a team led by Prof. Yang Liangbao from Hefei Institutes of Physical Science, Chinese Academy of Sciences used the nano-capillary pumping action to automatically capture the target molecules into a smaller gap and achieve highly sensitive Surface-Enhanced Raman Spectroscopy (SERS) detection by constructing a multilayer nanoparticle film to form a natural gap of less than 3 nm between the layers.

19 Jul 2022

Sex matters when it comes to immune responses to vaccines and viral infections

A review published in Frontiers in Aging analyzed the sex differences in the safety, effectiveness, and immunogenicity of influenza and COVID-19 vaccines in older individuals. It also analyzed the way sex brings about the modification of the impact of age-related factors on vaccination.

18 Jul 2022

Rice researchers use deactivated Cas9 proteins to synthetically trigger the transcription of genes

Rice University researchers have demonstrated that CRISPR-Cas9, increasingly famous as a gene-editing tool, can be employed in powerful additional ways in human cells.

18 Jul 2022

Research describes one of the ways the SARS-CoV-2 virus recruits cells to replicate

An article published in the journal Frontiers in Cellular and Infection Microbiology reports a study by researchers at the State University of Campinas (UNICAMP) and the University of São Paulo (USP) in Brazil showing how a human protein interacts with a SARS-CoV-2 protein, and describing one of the ways the virus that causes COVID-19 recruits cells to replicate.

18 Jul 2022

Study shows how insults deliver lexical 'mini-slaps in the face'

Hearing insults is like receiving a "mini slap in the face", regardless of the precise context the insult is made in.

18 Jul 2022

Wistar scientists reveal a novel ADAR1-SIRT1-p16INK4a axis in regulating cellular senescence

Aging and age-related disorders pose a complex challenge to the biomedical research community. To better understand how senescence is regulated is of high significance to promote healthy aging and treat age-associated disorders.

18 Jul 2022

Study offers new insights into brain metastases in patients with melanoma

Brain metastasis is one of the most common causes of cancer-related deaths and occurs very frequently in patients with advanced melanoma.

18 Jul 2022

The role of FTIR in protein analysis and biomedical applications

Professor Dr. Werner Mantele is the Professor of Biophysics at Goethe University and Frankfurt University. With over 30 years of experience with spectroscopy, Dr. Mantele is an internationally-recognized expert in the analysis and detection of molecules.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 18 Jul 2022

Cytokine-based cancer immunotherapy: current progress and future prospects

In this interview, News-Medical talks to Dr. Shuang Zhou about cytokine-base cancer immunotherapy, the current state of the field, and future prospects.

From Sino Biological Inc. 18 Jul 2022

Novel nanoligomer approach to treat severe COVID-19

Researchers discuss the biodistribution and safety of a novel nanoligomer SBCoV207, which was used to targeted miR-2392 in a murine model.

17 Jul 2022

Unique tool helps to study how the mechanical forces behind protein folding affect cancer spread

Talin is a protein that controls cellular attachment and movement, but its malfunctioning also allows cancer cells to spread. DCL1 is a tumor-suppressing protein. But scientists don't fully understand how either protein works – or what happens when they don't work the way they should.

15 Jul 2022

Proteins' wobbles, shakes and quivers play a key role in their ability to function

Johns Hopkins Medicine scientists report they have probed the atomic structure of proteins to add to evidence that the wobbles, shakes and quivers of proteins play a critical role in their ability to function.

15 Jul 2022

Study provides new insights into the process of memory recall

An unforgettable time at a restaurant is not just about the food. The odors, the decor, the sound of the band playing, the conversations, and many other features may combine to form a distinctive memory of the night.

15 Jul 2022

Tokyo Tech researchers develop the first synthetic mechanosensitive potassium channel

Intrigued by the properties of ion channel proteins commonly observed in cells, Tokyo Tech researchers have developed the first synthetic mechanosensitive potassium channel using a newly developed aromatic fluorinated amphiphilic cyclophane.

15 Jul 2022

New study calls for increased collaboration to build a more resilient global food supply

Increased demand for water will be the No. 1 threat to food security in the next 20 years, followed closely by heat waves, droughts, income inequality and political instability, according to a new University of Colorado Boulder-led study which calls for increased collaboration to build a more resilient global food supply.

15 Jul 2022

Life Science News

Researchers use high-speed atomic force microscopy to explore the binding mechanism of cadherins

CN Bio opens new laboratory facilities to extend Organ-on-a-chip contract research services capabilities

Researchers develop new SERS method for active capture of target molecules

Sex matters when it comes to immune responses to vaccines and viral infections

Rice researchers use deactivated Cas9 proteins to synthetically trigger the transcription of genes

Research describes one of the ways the SARS-CoV-2 virus recruits cells to replicate

Study shows how insults deliver lexical 'mini-slaps in the face'

Wistar scientists reveal a novel ADAR1-SIRT1-p16INK4a axis in regulating cellular senescence

Study offers new insights into brain metastases in patients with melanoma

The role of FTIR in protein analysis and biomedical applications

Cytokine-based cancer immunotherapy: current progress and future prospects

Novel nanoligomer approach to treat severe COVID-19

Unique tool helps to study how the mechanical forces behind protein folding affect cancer spread

Proteins' wobbles, shakes and quivers play a key role in their ability to function

Study provides new insights into the process of memory recall

Tokyo Tech researchers develop the first synthetic mechanosensitive potassium channel

New study calls for increased collaboration to build a more resilient global food supply

WHO issues an urgent call to accelerate access to genomics in resource-poor countries

Microplate optimised for magnetic bead separations

Pox viruses deliver proteins that directly interfere with the body's innate immune system

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