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SARS-CoV-2 mutations alter dynamics of neutralizing antibodies

A new study describes how monoclonal antibodies raised against SARS-CoV-2 are affected by mutations in the antibody binding site.

20 Aug 2021

SARS-CoV-2 lambda variant escapes immune response via spike mutations

A new study explores the mechanism by which the SARS-CoV-2 lambda variant has acquired immune evasion capabilities above that of the wildtype.

20 Aug 2021

Researchers identify key protein that plays an essential role in male fertility

Mammalian sperm cannot fertilize an egg from the get-go. It's an ability acquired only after insemination, during passage through the female reproductive tract, and requires two consecutive, time-sensitive processes to provide sperm with the physical and biochemical traits necessary to complete their fundamental job.

20 Aug 2021

Researchers identify genes associated with biochemical recurrence in prostate adenocarcinoma

Aging-US published "Identification of microenvironment related potential biomarkers of biochemical recurrence at 3 years after prostatectomy in prostate adenocarcinoma" which reported that the authors aimed to identify the potential prognostic genes in the prostate adenocarcinoma microenvironment and to estimate the causal effects simultaneously.

20 Aug 2021

New insights into opportunities and challenges of macrogenetics

The burgeoning field of macrogenetics is the focus of a new review published in Nature Reviews Genetics by a global, multidisciplinary team of researchers seeking to better answer fundamental biodiversity questions.

20 Aug 2021

New mouse line reveals the state of protein balance in the mammalian brain for the first time

Proteins are the "tools" of our cells – they are essential to all vital tasks. However, they are only able to do their jobs if they fold correctly and adopt their respective, very specific 3D structure.

20 Aug 2021

Study: PirB inhibits the self-renewal and differentiation capacities of neural stem cells

Aging-US published "PirB functions as an intrinsic suppressor in hippocampal neural stem cells" which reported that neural stem cells play pivotal roles during prenatal development and throughout life.

20 Aug 2021

Human waste-derived nutrient can help sustain agriculture, economies

The future connection between human waste, sanitation technology and sustainable agriculture is becoming more evident. According to research directed by University of Illinois Urbana-Champaign civil and environmental engineering professor Jeremy Guest, countries could be moving closer to using human waste as fertilizer, closing the loop to more circular, sustainable economies.

20 Aug 2021

Novel CRISPR-based technology for rapidly screening genes to understand human health and disease

Zebrafish- small, fast-growing creatures who share many of the same genes as humans- are instrumental to many biologists, who find them uniquely well suited for studying a wide range of questions, from how organisms develop to how the nervous system drives behavior.

20 Aug 2021

Bristol scientists show how laboratory evolution can give rise to highly efficient enzymes

Researchers at the University of Bristol have shown how laboratory evolution can give rise to highly efficient enzymes for new-to-nature reactions, opening the door for novel and more environmentally friendly ways to make drugs and other chemicals.

20 Aug 2021

Researchers use ancient mammalian proteins to develop mRNA delivery system

Using a family of mammalian proteins adopted from ancient retroviral legacy genes, researchers have developed a novel system for programmable intracellular mRNA delivery.

20 Aug 2021

Npas4 gene may be a master timekeeper for the brain's circadian clock

A gene called Npas4, already known to play a key role in balancing excitatory and inhibitory inputs in brain cells, appears to also be a master timekeeper for the brain's circadian clock, new research led by UT Southwestern scientists suggests.

20 Aug 2021

Research could enable clinicians to produce patient-matched cells for treating muscle-related diseases

Investigators who previously developed a recipe for turning skin cells into primitive muscle-like cells that can be maintained indefinitely in the lab without losing the potential to become mature muscle have now uncovered how this recipe works and what molecular changes it triggers within cells.

19 Aug 2021

Genetic nurture has a significant effect on child's educational success, study finds

A child's educational success depends on the genes that they haven't inherited from their parents, as well as the genes they have, according to a new study led by UCL researchers.

19 Aug 2021

Researchers discover glycan 'gates' that open to allow SARS-CoV-2 entry

Since the early days of the COVID pandemic, scientists have aggressively pursued the secrets of the mechanisms that allow severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to enter and infect healthy human cells.

19 Aug 2021

Scientists develop a new way to deliver molecular therapies to cells

Researchers from MIT, the McGovern Institute for Brain Research at MIT, the Howard Hughes Medical Institute, and the Broad Institute of MIT and Harvard have developed a new way to deliver molecular therapies to cells.

19 Aug 2021

Study identifies the cause and treatment for rare rheumatoid-like autoinflammatory condition

The absence of a protein that activates the body's antiviral defenses can cause a rare rheumatoid-like autoinflammatory condition that is treatable with an FDA-approved class of drugs known as TNF (tumor necrosis factor) inhibitors, a global research team led by Mount Sinai has found.

19 Aug 2021

Life Science News

SARS-CoV-2 mutations alter dynamics of neutralizing antibodies

SARS-CoV-2 lambda variant escapes immune response via spike mutations

Researchers identify key protein that plays an essential role in male fertility

Researchers identify genes associated with biochemical recurrence in prostate adenocarcinoma

New insights into opportunities and challenges of macrogenetics

New mouse line reveals the state of protein balance in the mammalian brain for the first time

Study: PirB inhibits the self-renewal and differentiation capacities of neural stem cells

Human waste-derived nutrient can help sustain agriculture, economies

Novel CRISPR-based technology for rapidly screening genes to understand human health and disease

Bristol scientists show how laboratory evolution can give rise to highly efficient enzymes

Researchers use ancient mammalian proteins to develop mRNA delivery system

Npas4 gene may be a master timekeeper for the brain's circadian clock

Research could enable clinicians to produce patient-matched cells for treating muscle-related diseases

Genetic nurture has a significant effect on child's educational success, study finds

Researchers discover glycan 'gates' that open to allow SARS-CoV-2 entry

Scientists develop a new way to deliver molecular therapies to cells

Study identifies the cause and treatment for rare rheumatoid-like autoinflammatory condition

Researchers identify antibodies that could protect against alphaviruses

Studies shed light on the versatility, precision, and sensitivity of quantitative analytical tools

Arteriolar niche used by breast cancer cells to prepare for metastasis

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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