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Predictive model detects patients who fit historical criteria for genetic testing

Patients who, perhaps unbeknownst to their health care providers, are in need of genetic testing for rare undiagnosed diseases can be identified en masse based on routine information in electronic health records (EHRs), a research team reported today in the journal Nature Medicine.

3 Jun 2021

Research opens alternative therapeutic avenues for treatment of chronic pain

Building on previous findings, scientists have demonstrated that conolidine interacts with the newly identified opioid receptor ACKR3/CXCR7.

3 Jun 2021

Scientists identify many existing drugs with antiviral activity against coronavirus

Mining the world's most comprehensive drug repurposing collection for COVID-19 therapies, scientists have identified 90 existing drugs or drug candidates with antiviral activity against the coronavirus that's driving the ongoing global pandemic.

3 Jun 2021

Study: Some Type 2 diabetes patients can benefit from bone marrow stem cell transplants

Type 2 diabetes patients who are not overweight and who have had the disorder for less than a decade can benefit from stromal stem cells transplanted from their own bone marrow, according to a study published today in STEM CELLS Translational Medicine.

3 Jun 2021

Streamline Cannabinoid Analyses with Restek’s New Neutrals Mix

Restek’s new cannabinoid 9-component mix streamlines cannabinoid analyses.

From Restek Corporation 3 Jun 2021

How bacterial cells have been engineered to produce virus-resistant synthetic polymers

A recent Science paper discusses the utilization of a previously reported synthetic Escherichia coli to produce virus-resistant synthetic polymers.

3 Jun 2021

Optimized Tube Plate for Enzyme Studies

BioChromato Inc. has developed an enzyme assay product - the RAPID Tube Plate 600 (TP-600) that is helping deliver outstanding results in in vitro metabolic stability studies.

From BioChromato Inc. 3 Jun 2021

Study shows how the physical nature of genome changes before and after cell differentiation

The organization of the human genome relies on physics of different states of matter - such as liquid and solid - a team of scientists has discovered. The findings, which reveal how the physical nature of the genome changes as cells transform to serve specific functions, point to new ways to potentially better understand disease and to create improved therapies for cancer and genetic disorders.

3 Jun 2021

Epigenetic regulation affects the 3D structure of genome

All the cells of an organism share the same DNA sequence, but their functions, shapes or even lifespans vary greatly. This happens because each cell "reads" different chapters of the genome, thus producing alternative sets of proteins and embarking on different paths.

3 Jun 2021

Scientists develop new gene drive with a built-in genetic barrier

CRISPR-based technologies offer enormous potential to benefit human health and safety, from disease eradication to fortified food supplies. As one example, CRISPR-based gene drives, which are engineered to spread specific traits through targeted populations, are being developed to stop the transmission of devastating diseases such as malaria and dengue fever.

3 Jun 2021

Researchers gain new insights into the structure of cancer-promoting Ras protein

Almost all attempts to use the Ras protein as a point of attack for medications have so far failed. New knowledge concerning its structure is raising hopes of options in the development of medications.

2 Jun 2021

Newly identified protein could become a target for future cancer treatments

Researchers at the Francis Crick Institute have identified a protein that helps tumours evade the immune system and, in certain types of cancers, is linked to a poorer chance of survival. The protein could become a target for future cancer treatments.

2 Jun 2021

Gut-brain communication by distinct nerve cells differently controls satiety and blood sugar levels

The gut and the brain communicate with each other in order to adapt satiety and blood sugar levels during food consumption.

2 Jun 2021

Sinai Health researchers provide an ultra-detailed look at the organization of human cells

Researchers from Sinai Health have published a study providing an ultra-detailed look at the organization of a living human cell, providing a new tool that can help scientists around the world better understand what happens during disease.

2 Jun 2021

Study uncovers mechanisms by which microRNAs drive atherogenesis in a cell-type-specific manner

Researchers at the University of Eastern Finland have uncovered potential mechanisms by which microRNAs (miRNA) drive atherogenesis in a cell-type-specific manner.

2 Jun 2021

Cmed Technology Adds More Capabilities to its Encapsia Platform and Reports Increased Demand for Use in Decentralized Trials (DCT)

Innovative technology for clinical trials is now, more than ever, necessary to deliver decentralized trials (DCT) and enable design of hybrid protocols that support trial continuity and patient-centricity.

2 Jun 2021

Aptamer Group and PinotBio collaborate to develop new therapeutic drug conjugates

Aptamer Group Limited and PinotBio today announce that they have entered into a strategic collaboration agreement.

From Aptamer Group 2 Jun 2021

Study provides new knowledge about molecular mechanisms underlying human traits, diseases

A new study analyzing the association between an individual's genetics (genotype) and their observable characteristics resulting from the interaction of genetics and the environment (phenotype), contributes new knowledge to the understanding of human complex traits and diseases.

1 Jun 2021

NUS researchers develop a way to automate the production of pharmaceutical small molecules

The discovery and development of new small-molecule compounds for therapeutic use involves a huge investment of time, effort and resources.

1 Jun 2021

UCL researchers measure mass of human chromosomes with X-rays for the first time

The mass of human chromosomes, which contain the instructions for life in nearly every cell of our bodies, has been measured with X-rays for the first time in a new study led by UCL researchers.

1 Jun 2021

Life Science News

Predictive model detects patients who fit historical criteria for genetic testing

Research opens alternative therapeutic avenues for treatment of chronic pain

Scientists identify many existing drugs with antiviral activity against coronavirus

Study: Some Type 2 diabetes patients can benefit from bone marrow stem cell transplants

Streamline Cannabinoid Analyses with Restek’s New Neutrals Mix

How bacterial cells have been engineered to produce virus-resistant synthetic polymers

Optimized Tube Plate for Enzyme Studies

Study shows how the physical nature of genome changes before and after cell differentiation

Epigenetic regulation affects the 3D structure of genome

Scientists develop new gene drive with a built-in genetic barrier

Researchers gain new insights into the structure of cancer-promoting Ras protein

Newly identified protein could become a target for future cancer treatments

Gut-brain communication by distinct nerve cells differently controls satiety and blood sugar levels

Sinai Health researchers provide an ultra-detailed look at the organization of human cells

Study uncovers mechanisms by which microRNAs drive atherogenesis in a cell-type-specific manner

Cmed Technology Adds More Capabilities to its Encapsia Platform and Reports Increased Demand for Use in Decentralized Trials (DCT)

Aptamer Group and PinotBio collaborate to develop new therapeutic drug conjugates

Study provides new knowledge about molecular mechanisms underlying human traits, diseases

NUS researchers develop a way to automate the production of pharmaceutical small molecules

UCL researchers measure mass of human chromosomes with X-rays for the first time

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

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