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Researchers investigate relationship between immune defenses and body size

What species is better at fighting an infection, a mouse or an elephant? Body size is one of the most noticeable differences among species, but relationships between immune defenses and body size have largely been unstudied.

25 Sep 2019

Scientists use new single-cell genetic technique to tackle potential drug resistance

Using a new technique that can identify genetic profiles of individual cells, University of Notre Dame researchers modeled a breast cancer tumor's potential resistance to a drug, and then identified a drug combination that reversed that resistance.

25 Sep 2019

Detailed imaging of trypanosome paves way for new opportunities to combat sleeping sickness

The parasite trypanosome does not swim through a blood vessel as has always been assumed, it can simply be carried along with the flow.

25 Sep 2019

Streamlining the compound ordering process for life scientists in the US

Molport has announced its expansion into the US with the opening of MolPort Inc., which will streamline the compound ordering process for US customers.

25 Sep 2019

Monitoring the Human Proteome using diaPASEF

In this interview, Dr. Hannes Röst describes how his lab are using diaPASEF to monitor the human proteome throughout a person's lifetime, and how machine learning could be used to analyze the data.

From Bruker Life Sciences Mass Spectrometry 25 Sep 2019

Reactivating ‘tumor suppressor’ genes could offer new therapeutic approach for cancer

Scientists have developed a method which is able to switch ‘tumor suppressor’ genes back on after they have been silenced by cancer cells.

25 Sep 2019

Improved mapping of genomes from 1,000 Swedish individuals

In so-called whole genome sequencing, surveys are made of the total genome of an individual. It is still relatively rare in healthcare today, but it occurs at an increasing rate, for example in order to make an accurate diagnosis in the case of a rare disease.

25 Sep 2019

Openspecimen chosen to manage ARTB's biospecimen library

The Auckland Region Tissue Bank is a critical component in New Zealand’s medical research infrastructure. As a central facility for storing blood and tissue samples, they have a library that could hold the secrets to unlocking cures for existing and future chronic diseases and illnesses.

25 Sep 2019

Native American DNA is still carried by descendants of early Europeans and Africans in the U.S.

Many people in the U.S. do not belong to Native American communities but still carry bits of Native American DNA, inherited from European and African ancestors who had children with indigenous individuals during colonization and settlement.

From PLOS ONE 25 Sep 2019

Study shows how AF4-MALS-UV can separate and size large AAV aggregates

Postnova Analytics has published a new applications study that reports on how Asymmetric Flow Field Flow Fractionation (AF4) coupled with multi-angle light scattering (MALS) and Ultraviolet (UV) detectors can be used to quantify Adeno-Associated Virus (AAV) aggregation.

From Postnova Analytics 25 Sep 2019

TUM researchers reveal how chaperones detect immature immune signaling proteins

The cells of our immune system constantly communicate with one another by exchanging complex protein molecules.

24 Sep 2019

Tapeworms need their head for stem cell-driven regeneration

Scientists have identified the stem cells that allow tapeworms to regenerate and found that their location in proximity to the head is essential, according to a new study in eLife.

24 Sep 2019

Study uncovers new DNA sequences in Swedish genomes

People - or more specifically just Swedes - are more like chimpanzees than previously known. This is indicated in a genetic mapping of one thousand Swedish individuals, where new DNA sequences that should be included in the reference genome have been identified.

24 Sep 2019

Ear's tiny outer hair cells regulate sound sensitivity, study shows

The ear’s tiny outer hair cells adjust the sensitivity of neighboring inner hair cells to sound levels rather than acting like an amplifier, suggests a new study published today in eLife.

24 Sep 2019

Iranian population is highly heterogeneous than previously believed, genome study shows

An international research team including scientists from the University of Cologne, Germany, numerous Iranian universities and the University of Sydney, Australia, has shown that today's Iranian population is composed of partially highly heterogeneous ethnic groups, exhibiting a high degree of genetic variation.

24 Sep 2019