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Group of genes linked to longer lifespan in fruit flies discovered

Alexey Moskalev, Ph.D., Head of the Laboratory of Geroprotective and Radioprotective technologies, and co-authors from the Institute of biology of Komi Science Center of RAS, the Engelgard's Institute of molecular biology of RAS and Moscow Institute of Physics and Technology published a scientific article titled "Transcriptome Analysis of Long-lived Drosophila melanogaster E(z) Mutants Sheds Light on the Molecular Mechanisms of Longevity" in Nature Scientific Reports - the leading international multidisciplinary weekly journal.

19 Jul 2019

How genetic differences in Epstein-Barr virus strains alter the way it behaves

Researchers at the University of Sussex have identified how differences in the genetic sequence of the two main strains of the cancer-associated Epstein-Barr virus can alter the way the virus behaves when it infects white blood cells.

19 Jul 2019

AEBP1 gene may play key role in the development and severity of liver disease

Researchers have found that a gene known as AEBP1 may play a central role in the development, severity and potential treatment of liver disease, according to a study by Temple University, the Geisinger Obesity Institute and the Translational Genomics Research Institute, an affiliate of City of Hope.

18 Jul 2019

Researchers develop a more precise version of CRISPR-Cas9 gene-editing system

A gene defect in humans causes progressive hearing loss in humans, resulting in deafness by their mid-20s. The same genetic mutation causes deafness in the Beethoven-mouse model.

18 Jul 2019

Researchers reveal molecular cause for severe multi-organ disorder

Three unrelated families on three continents (from continental Portugal, the United States and Brazil), all with healthy ancestors, had children with a very rare disease.

18 Jul 2019

Research team detects novel mechanism of inheritance

Non-Mendelian, oligogenic inheritance could bean unrecognized and important element for occurrence ofhereditary retinal degenerations (HRDs, comprising retinitis pigmentosa) which are caused by ultra-rare mutations and cause progressive blindness.

18 Jul 2019

Study defines how diarrhea-causing rotavirus initially interacts with the host

Research by the Department of Microbiology of the University of Valencia, the Institute of Biomedicine of Valencia and the Institute of Agrochemistry and Food Technology of the CSIC has defined the initial interaction of human rotavirus P [8] (the main cause of gastroenteritis) with the recipients of the intestine.

18 Jul 2019

Novel insight into microRNA function can be crucial for the development of gene therapy

Scientists at the University of Eastern Finland and the University of Oxford have shown that small RNA molecules occurring naturally in cells, i.e. microRNAs, are also abundant in cell nuclei.

18 Jul 2019

Cancer stem cells elude the body's immune cells by deactivating danger detector

Acute myeloid leukemia stem cells elude the body's immune cells by deactivating a danger detector. The underlying mechanisms and the potential new therapeutic approaches that this gives rise to have been detailed in the journal Nature by researchers from the University of Basel and University Hospital Basel in collaboration with colleagues in Germany.

18 Jul 2019

New research could help design algae that produces fuels and cleanup chemicals

It's a case of grand larceny that could lead to new fuels and cleanup chemicals. Ten species of red algae stole about 1 percent of their genes from bacteria to cope with toxic metals and salt stress in hot springs, according to a study in the journal eLife.

18 Jul 2019

Study: Megakaryocytes play an important role in cell migration

Hematopoiesis is the process of forming blood cells, which occurs predominantly in the bone marrow. The bone marrow produces all types of blood cells: red blood cells, platelets, and white blood cells.

18 Jul 2019

Scientists discover how resistance to the chemotherapy drug 5-fluorouracil arises

Australian researchers have unlocked the mystery as to why the chemotherapy drug 5-Fluorouracil is not effective at treating certain cancers.

17 Jul 2019

Molecular switches may control lifespan and healthspan separately, genetic discovery suggests

Aging research indicates that better healthspan--the quality of life as we age--may be more important than lifespan.

17 Jul 2019

IT Faces the Digital Pathology Data Tsunami

Digital pathology is the viewing, analyzing, and managing of digitalized pathology slides with computer technology.

From Huron Digital Pathology 17 Jul 2019

Researchers identify chemical compounds that increase stability of haploid cell

Since the emergence of molecular genetics more than fifty years ago, scientists have tried to isolate haploid mammalian cells, that is, cells with half the number of chromosomes contained in somatic cells. Haploid cells are a powerful genetic tool to analyze gene function.

17 Jul 2019

Slug serves as 'command central' for determining breast stem cell health

A new study published in Cell Reports found that a transcription factor called Slug serves as 'command central' for determining breast stem cell health, regulating both stem cell activity and repair of DNA damage.

17 Jul 2019

Study identifies genomic differences that impact response to Cryptococcus infection

Cryptococcus neoformans is a fungal pathogen that infects people with weakened immune systems, particularly those with advanced HIV/AIDS. New University of Minnesota Medical Research could mean a better understanding of this infection and potentially better treatments for patients.

16 Jul 2019