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Mutant live attenuated Ebola virus elicits protective immunity in monkeys

Inoculation with an Ebola virus that has mutations in a protein called VP35 does not cause disease and elicits protection in monkeys, researchers show September 17 in the journal Cell Reports.

17 Sep 2019

Study finds dietary fiber components that encourage growth of beneficial gut microbes

Humans choose food based on the way it looks, smells, and tastes. But the microbes in our guts use a different classification system--one that is based on the molecular components that make up different fibers.

17 Sep 2019

New Thermo Scientific General Purpose Pro Centrifuge Series delivers improved performance and safety

Scientists working across biopharmaceutical, academic research and clinical diagnostic applications can now access a series of sophisticated next-generation centrifugation systems designed to offer improved performance, reliability, consistency and safety.

From Thermo Fisher Scientific Inc. 17 Sep 2019

Attana invited to showcase latest applications at National University of Singapore's Life Sciences day

Attana is invited to present at the National University of Singapore's Life Sciences Institute Core Facilities Day - NUS Medical Sciences Cluster on Thursday September 20th. In particular, Attana is invited to show Attana's leading applications for interaction characterization of CAR-T cells and tumor tissues.

17 Sep 2019

Bone marrow-derived cells also travel to the womb to help pregnancy

Bone marrow-derived cells play a role in changes to the mouse uterus before and during pregnancy, enabling implantation of the embryo and reducing pregnancy loss, according to research published September 12 in the open-access journal PLOS Biology.

From PLOS ONE 17 Sep 2019

Strongest genetic risk factor for Alzheimer’s disease impairs function of human microglia

A study carried out with a new human stem cell-derived model reveals that the most prevalent genetic risk factor of Alzheimer’s disease (AD), apolipoprotein E4 (APOE4), impairs the function of human brain immune cells, microglia. These findings pave the way for new, effective treatment approaches for AD. The results were published in Stem Cell Reports.

17 Sep 2019

Label-free laser microscopy technique accurately detects ovarian metastatic cancer

Women undergoing treatment for ovarian cancer are checked for tumor cells that may have spread to surrounding tissues, but current technologies miss very small metastatic areas. Now a laser microscopy technique is able to identify these regions with great accuracy.

17 Sep 2019

Sleep deprivation affects fat metabolism

We're all a little short on sleep during the work week. A new study adds to the mounting evidence about just how harmful lack of sleep can be.

16 Sep 2019

Cellular metabolic overactivity leads to inflammation, research reveals

Scientists describe a previously unknown disorder of the immune system: in a distinct subset of immune cells from patients with primary immunodeficiency, cellular respiration is significantly increased.

16 Sep 2019

New platform uses nanoparticles to deliver anti-cancer agent to cells

Scientists from the University of Cambridge have developed a platform that uses nanoparticles known as metal-organic frameworks to deliver a promising anti-cancer agent to cells.

16 Sep 2019

Scientists to study how cellular circuits recycle proteins

Human cells break down excess or unusable proteins into amino acids they can use, but scientists do not understand the process.

16 Sep 2019

Biologists observe how microtubules branch in new directions in animal cells

Cell biologist Thomas Maresca and senior research fellow Vikash Verma at the University of Massachusetts Amherst say they have, for the first time, directly observed and recorded in animal cells a pathway called branching microtubule nucleation, a mechanism in cell division that had been imaged in cellular extracts and plant cells but not directly observed in animal cells.

16 Sep 2019

Accelerating drug discovery process to help patients

An international research team has developed a new strategy that can predict the potential clinical implications of new therapeutic compounds based on simple cellular responses.

15 Sep 2019

West Nile Virus samples found 10 miles apart came from different places, NAU scientist finds

After sequencing more than 400 different genomes of the West Nile Virus, an NAU scientist discovered the two reports of West Nile Virus in Coconino County came from two different places. One migrated north from the Phoenix area. The other is a bit more of a mystery.

15 Sep 2019