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Researchers map bone-marrow microenvironment to shed new light on leukemia

Stem cells are surrounded and protected by the stem-cell niche - the microenvironment - of the tissue in which they are found.

24 May 2019

New lithography method for producing complex tissues and organs

The production of artificial organs is a hot research topic. In the near future, artificial organs will compensate for the lack of organ donations and replace animal experiments.

23 May 2019

LM20 Microfluidizer efficiently disrupts a broad range of cell types

Analytik reports on how the School of Biological & Chemical Sciences at Queen Mary University, London has been using a LM20 Microfluidizer for cell disruption of a broad range of cell types including E. coli, Yeasts and Diatom.

From Analytik Ltd 23 May 2019

Longas offers Morphoseq technology for highly accurate long read sequencing on short read NGS platforms

Longas Technologies Pty Ltd, a developer of Next Generation Sequencing technologies, has provided details on its Morphoseq library prep and associated software technology at the ‘Sequencing, Finishing and Analysis in the Future’ meeting, May 21 – 23, Santa Fe, NM, USA, that enables long read sequencing on short read NGS platforms.

23 May 2019

Spatial configuration of the genome is not inherited, but set up during embryogenesis

The architecture of the DNA-protein complexes that make up the genome in each cell nucleus regulates the course of early embryonic development.

23 May 2019

Scientists uncover unique set of genes that play a role in muscle cellular gene regulation

York University scientists have uncovered a unique set of genes that play a role in muscle cellular gene expression and differentiation which could lead to new therapeutic targets to prevent the spread of muscle cancer.

23 May 2019

Large study links rare DNA alterations to type 2 diabetes

An international consortium of scientists has analyzed protein-coding genes from nearly 46,000 people, linking rare DNA alterations to type 2 diabetes.

23 May 2019

Genetic switch that controls conversion of bad to good fat identified

Fat cells. They are the bane of a dieter's existence, but fat is important. Previous studies showed the subcutaneous white fat cells can transform to brown and beige varieties when exposed to cold stress.

23 May 2019

Scientists develop new genetic tool to modify and understand gene function

Scientists of the National Center for Cardiovascular Research led by Rui Benedito have developed a new genetic tool (iSuRe-Cre) that provides certainty in Cre-inducible genetic modifications, a key technique for understanding gene function.

22 May 2019

Yeast species thrives, despite losing DNA repair genes years ago

Researchers have discovered an ancient species of budding yeast that has lost dozens of DNA repair genes, without any adverse effects.

22 May 2019

Newly discovered molecules safely halt the gene editing process

Scientists have discovered two non-toxic molecules that safely halt the CRISPR-Cas9 gene editing process.

22 May 2019

Scientists unravel how DNA organizes and preserves genetic information

Two scientists at the Johns Hopkins University School of Medicine have unraveled aspects of how DNA organizes and preserves genetic information.

From Johns Hopkins Medicine 22 May 2019

Ziath announces opening of direct operations in the U.S.

Instrumentation control and information management product specialists - Ziath has announced the opening of direct operations in the US with the appointment of a general manager.

From Ziath Ltd 22 May 2019

UW researchers use molecular tethers, chemical 'light sabers' for tissue engineering

Tissue engineering could transform medicine. Instead of waiting for our bodies to regrow or repair damage after an injury or disease, scientists could grow complex, fully functional tissues in a laboratory for transplantation into patients.

22 May 2019

Researchers decode how molecular escorts help prevent cancer

The anti-tumor protein p53 can decide on the life or death of a cell: If it detects damage in the cell's genome, the protein pushes the cell to suicide.

22 May 2019

Study provides new insights into key beneficial function of small ancient protein

Cell boundaries are made of lipids. When cells are severely damaged, these lipids need to be rapidly removed to avoid toxicity and facilitate tissue healing. Researchers have discovered that a small ancient protein, Serum Amyloid A (SAA), plays a previously unknown key role in this vital process.

21 May 2019

Cutting the test time for disease biomarkers using extracellular vesicles

When an individual has cancer, or any number of other diseases, early detection can make a huge difference in the outcome. A research team led by the University of Notre Dame is working to cut the test time for disease biomarkers.

21 May 2019

Scientists create bacteria with man-made DNA

In a landmark research study, a living organism (E. coli) has been made using entirely human-made DNA.

21 May 2019

Synbiosis to showcase new AutoCOL fully automated colony counting system at ASM Microbe 2019

Synbiosis, a long-established, expert manufacturer of automated microbiological systems, is delighted to announce its new AutoCOL fully automated colony counting system will be on show for the first time at Booth 4630, ASM Microbe 2019, on 21-23 June.

From Synbiosis 21 May 2019

Researchers discuss how time of day affects the severity of illness

In a review published May 17 in the journal Trends in Immunology, researchers discuss how time of day affects the severity of afflictions ranging from allergies to heart attacks.

21 May 2019