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IU team makes significant contributions to constructing a Human Reference Atlas

Katy Börner's team from the Luddy School of Informatics, Computing, and Engineering's Cyberinfrastructure for Network Science Center has made significant contributions to constructing a Human Reference Atlas and has led or co-authored six research articles in a just-released HuBMAP package in Nature.

21 Jul 2023

New $7 million grant supports research on how environmental chemicals impact gut microbiome

Worldwide, high rates of obesity and other inflammatory conditions are associated with increased risk for cancer, cardiovascular disease and type 2 diabetes.

21 Jul 2023

New compound shows promise in stopping breast cancer metastasis

Researchers from the University of Liverpool have created a biomedical compound that has the potential to stop the spread of breast cancer. A recently published paper details these early findings.

21 Jul 2023

Researchers discover how ribosomes regulate protein production

The human body consists of numerous trillions of cells, and 60 percent of the energy used within a cell is dedicated to a specific molecular machine.

21 Jul 2023

ARMGO Pharma Enrolls First Patient in Phase 2 Trial of ARM210 for the Treatment of Catecholaminergic Polymorphic Ventricular Tachycardia

Trial to investigate the safety and efficacy of ARM210 for the treatment of Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT).

21 Jul 2023

AI-powered study pinpoints genes that shape bones

Using artificial intelligence to analyze tens of thousands of X-ray images and genetic sequences, researchers from The University of Texas at Austin and New York Genome Center have been able to pinpoint the genes that shape our skeletons, from the width of our shoulders to the length of our legs.

20 Jul 2023

Researchers develop novel system to identify new therapeutics for familial hypercholesterolemia

The Mona Lisa, painted by the Italian artist Leonardo da Vinci, is one of the most recognizable paintings in the world. But many people would be surprised to learn that this painting offers the first evidence of a disease called familial hypercholesterolemia (FH).

20 Jul 2023

Study finds cell-free RNA can be used to predict preeclampsia

Preeclampsia is a serious pregnancy disorder, marked by high blood pressure and the presence of proteins in urine, affecting between 2% and 4% of pregnant women worldwide, leading to about 46,000 maternal deaths and about 500,000 fetal and newborn deaths each year.

20 Jul 2023

New mRNA-based malaria vaccine shows promise in preclinical trials

Trans-Tasman research collaborators from Te Herenga Waka-; Victoria University of Wellington's Ferrier Research Institute and the Malaghan Institute of Medical Research in New Zealand, and the Peter Doherty Institute for Infection and Immunity in Australia have developed an mRNA-based vaccine that can effectively target and stimulate protective immune cell responses against the malaria-causing parasite Plasmodium in preclinical models.

20 Jul 2023

Research illuminates the genetic basis of human skeletal proportions

Combining data from full-body x-ray images and associated genomic data from more than 30,000 UK Biobank participants, researchers have helped illuminate the genetic basis of human skeletal proportions.

20 Jul 2023

Cells communicate in waves to coordinate movement

Like us, cells communicate. Well, in their own special way. Using waves as their common language, cells tell one another where and when to move.

20 Jul 2023

Researchers discover new way to target bacterial cell wall

The bacterial cell wall must be constantly remodeled in order to grow and divide. This involves the close coordination of lytic enzymes and peptidoglycan synthesis.

20 Jul 2023

Study reveals a genetic basis for asymptomatic SARS-CoV-2 infection

People who contract COVID-19 but never develop symptoms – the so-called super dodgers – may have a genetic ace up their sleeve.

20 Jul 2023

Using single-cell mass spectrometry to study antimicrobial treatment failure

Laura-Isobel McCall, Ph.D., and Zhibo Yang, Ph.D., co-principal investigators and associate professors of chemistry and biochemistry in the Dodge Family College of Arts and Sciences at the University of Oklahoma, have been awarded a prestigious R01 grant from the National Institutes of Health for their project, "Novel single-cell mass spectrometry to assess the role of intracellular drug concentration and metabolism in antimicrobial treatment failure."

19 Jul 2023

New cellular atlas of the kidney sheds light on disease

Research is shedding light on kidneys, their critical functions, and predictors of disease.

19 Jul 2023

Study explores how ultraviolet radiation can alter the microstructure of human skin

Received wisdom says that staying out in the sun too long can make your skin tougher over time. Think about the "leathery" complexions of farmers, road crews and others who work long hours outdoors, or someone who spends too much time in tanning booths, or too much time on the beach during the summer.

19 Jul 2023

New refget version improves reliability of genomic data analysis

A widely-used tool that finds the exact references needed to pinpoint differences in our DNA just got a refresh.

19 Jul 2023

Scientists discover new details about RNA editing in single-celled, disease-causing parasite

As molecular biologists at Boston University and as husband and wife, Ruslan Afasizhev and Inna Afasizheva, have worked together for decades. Together, they have published dozens of papers on the mechanics of mitochondrial DNA and RNA in a single-celled, disease-causing parasite called Trypanosoma brucei.

19 Jul 2023

Neuroscientists discover new brain cells that help correct navigational errors

During routine navigation in daily life, our brains use spatial mapping and memory to guide us from point A to point B. Just as routine: making a mistake in navigation that requires a course correction.

19 Jul 2023

New kidney tissue atlas could advance understanding of kidney injury and disease

Researchers at Washington University School of Medicine in St. Louis helped lead a major study, funded by the National Institutes of Health (NIH), that uncovered rich cellular and molecular diversity in healthy and diseased kidneys, creating a kidney tissue atlas that will help further understanding of kidney injury and disease.

19 Jul 2023