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Glaucoma and cell death: an interview with Dr. Vivek Gupta

Glaucoma is normally caused by increased pressure of aqueous humour fluid in the eye. A defining feature of this disease is destruction of a particular type of cells in the retina called retinal ganglion cells and excavation of the optic disc region.

31 Aug 2012

Type 2 diabetics with normoalbuminuria more likely to develop heart problems

In individuals with type 2 diabetes, any degree of measurable urinary protein excretion—even in what is considered the normal range—increases their risk of experiencing heart problems, according to a study appearing in an upcoming issue of new study in the Journal of the American Society of Nephrology (JASN).

31 Aug 2012

Weill Cornell Medical College receives three new research grants for translational blood cancer study

Weill Cornell Medical College has been awarded three new research grants from the Leukemia & Lymphoma Society totaling $1.8 million. The funds will support critically-needed translational research for blood cancers, accelerating promising discoveries from the laboratory to the patient's bedside.

31 Aug 2012

Study confirms link between hormone replacement therapy use and breast cancer

The Million Women Study is a study, conducted by UK researchers, of women's health analyzing data from more than one million women aged 50 and over. It is a collaborative project between Cancer Research UK and the National Health Service (NHS), with additional funding from the Medical Research Council (UK).

31 Aug 2012

Healthy diets during infancy and early childhood can prevent obesity in future

Rats born to mothers fed high-fat diets but who get normal levels of fat in their diets right after birth avoid obesity and its related disorders as adults, according to new Johns Hopkins research.

31 Aug 2012

WellStar Health System, Aetna sign multiyear contract agreement

Aetna and WellStar Health System of Marietta, Ga. announced today that they have reached agreement on a multiyear contract extension. Under the agreement, members of Aetna's commercial plans will be able to continue to receive covered services, at in-network rates, from WellStar's hospitals and physicians in the greater Atlanta area.

31 Aug 2012

Impulsive and compulsive personality traits linked with traumatic upbringing during childhood

Previous research has shown that personality traits such as impulsivity or compulsiveness are indicators of an increased risk of addiction. Now, new research from the University of Cambridge suggests that these impulsive and compulsive personality traits are also associated with a traumatic upbringing during childhood.

31 Aug 2012

Less than half of U.S. schools address pandemic preparedness in their school plan

Less than half of U.S. schools address pandemic preparedness in their school plan, and only 40 percent have updated their school plan since the 2009 H1N1 pandemic, according to a study published in the September issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC).

31 Aug 2012

Soligenix’s RiVax induces greater ricin neutralizing antibody levels in humans

Soligenix, Inc., a development stage biopharmaceutical company, announced today the results of a Phase 1B clinical trial of an aluminum hydroxide (Alum) adjuvanted formulation of RiVax, designed to improve the immunogenicity of the vaccine.

31 Aug 2012

Renal artery stent revascularization reduces blood pressure in patients with severe hypertension

Patients with uncontrolled renovascular hypertension saw a significant improvement in their blood pressure with renal artery stent deployment. The multicenter HERCULES trial, evaluating the safety and effectiveness of the RX Herculink Elite Stent, found that patients with higher blood pressure levels at baseline had the most dramatic reduction in blood pressure following intervention.

31 Aug 2012

FDA approves Ironwood’s LINZESS to treat irritable bowel syndrome with constipation

Ironwood Pharmaceuticals, Inc. and Forest Laboratories, Inc. announced today that LINZESS (linaclotide) was approved by the U.S. Food and Drug Administration (FDA) as a once-daily treatment for adult men and women suffering from irritable bowel syndrome with constipation (IBS-C) or chronic idiopathic constipation (CIC).

31 Aug 2012

Researchers discover new immune response mechanism during infection

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered a new "first response" mechanism that the immune system uses to respond to infection. The findings challenge the current understanding of immunity and could lead to new strategies for boosting effectiveness of all vaccines. The study, conducted in mice, published online today in the journal Immunity.

31 Aug 2012

Park Nicollet, HealthPartners sign merger agreement

HealthPartners and Park Nicollet Health Services announced today that their boards of directors have signed an agreement to combine their organizations and create a comprehensive, integrated health care delivery and financing organization serving the entire Twin Cities metro area and western Wisconsin.

31 Aug 2012

Studies examine how PML gene regulates the fatty acid oxidation pathway

Two papers led by scientific teams from the Cancer Genetics Program at Beth Israel Deaconess Medical Center (BIDMC) shed new light on the genetic mechanisms underlying cellular energy and metabolism and, at the same time, highlight both the challenges and opportunities of genetic approaches to cancer treatment.

31 Aug 2012

Tips for parents to recognize signs of childhood obstructive sleep apnea

With school days upon us, a good night's sleep should be on the top of each child's list of supplies. But for some children, getting the rest they need means more than an early bedtime. At Clarity Allergy Center in Chicago, allergy, asthma, and immunology expert, Dr. Brian Rotskoff, is helping parents recognize the signs of childhood obstructive sleep apnea by carefully monitoring childhood snoring and childhood nasal allergies.

31 Aug 2012

MidCap, EpiCept amend Loan and Security Agreement

EpiCept Corporation announced today that it has amended the Company's Loan and Security Agreement with MidCap Financial, LLC effective August 27, 2012.

31 Aug 2012

Bayer submits regorafenib NDA with FDA for treatment of metastatic and/or unresectable GIST

Bayer HealthCare and Onyx Pharmaceuticals today announced that Bayer HealthCare has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for the oral multi-kinase inhibitor regorafenib for the treatment of metastatic and/or unresectable gastrointestinal stromal tumors (GIST) in patients whose disease has progressed despite prior treatment.

31 Aug 2012

U.S. lags three other industrialized nations in potentially preventable death rates

The United States lags three other industrialized nations-France, Germany, and the United Kingdom-in its potentially preventable death rate, and in the pace of improvement in preventing deaths that could have been avoided with timely and effective health care, according to a Commonwealth Fund-supported study published as a web first online today in Health Affairs.

31 Aug 2012

Study explains how FPGS increases effectiveness of pemetrexed in mesothelioma patients

Previous studies have hypothesized that low levels of the enzyme thymidylate synthase (TS) likely mark patients who will benefit from the drug pemetrexed - but results have been inconclusive at best and at times contradictory. A University of Colorado Cancer Center study recently published in the Journal of Thoracic Oncology provides an explanation why: only in combination with high levels of a second enzyme, FPGS, does low TS predict response to pemetrexed in patients with malignant pleural mesothelioma.

31 Aug 2012

Scientists open new front against cause of sleeping sickness

Scientists of the Antwerp Institute of Tropical Medicine (ITG) opened a new front against the cause of sleeping sickness. This parasite is transmitted between humans by tsetse flies. The researchers learned a bacterium living in those flies how to produce antibodies against the parasite. Application in the field is still a long way of, but the technique shows quite some promise.

31 Aug 2012

Medical News

Glaucoma and cell death: an interview with Dr. Vivek Gupta

Type 2 diabetics with normoalbuminuria more likely to develop heart problems

Weill Cornell Medical College receives three new research grants for translational blood cancer study

Study confirms link between hormone replacement therapy use and breast cancer

Healthy diets during infancy and early childhood can prevent obesity in future

WellStar Health System, Aetna sign multiyear contract agreement

Impulsive and compulsive personality traits linked with traumatic upbringing during childhood

Less than half of U.S. schools address pandemic preparedness in their school plan

Soligenix’s RiVax induces greater ricin neutralizing antibody levels in humans

Renal artery stent revascularization reduces blood pressure in patients with severe hypertension

FDA approves Ironwood’s LINZESS to treat irritable bowel syndrome with constipation

Researchers discover new immune response mechanism during infection

Park Nicollet, HealthPartners sign merger agreement

Studies examine how PML gene regulates the fatty acid oxidation pathway

Tips for parents to recognize signs of childhood obstructive sleep apnea

MidCap, EpiCept amend Loan and Security Agreement

Bayer submits regorafenib NDA with FDA for treatment of metastatic and/or unresectable GIST

U.S. lags three other industrialized nations in potentially preventable death rates

Study explains how FPGS increases effectiveness of pemetrexed in mesothelioma patients

Scientists open new front against cause of sleeping sickness

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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