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Researchers discover how tamoxifen-resistant breast-cancer cells grow and proliferate

A study by researchers at the Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) has discovered how tamoxifen-resistant breast-cancer cells grow and proliferate.

31 Aug 2012

Young undocumented immigrants allowed to stay in U.S. are still ineligible for Obamacare benefits

A new CMS rule aims to ensure that illegal immigrants exempted from deportation under the Obama administration's June 15 policy change on immigration will not qualify for subsidized coverage under either high-risk insurance pools or state-based exchanges.

31 Aug 2012

Quest Diagnostics announces availability of TERC test for cervical cancer

Quest Diagnostics, the world's leading provider of diagnostic testing, information and services, today announced the availability of a new laboratory test that identifies molecular changes to cervical cells that increase the likelihood a woman may develop cervical cancer.

From Quest Diagnostics 31 Aug 2012

PD0325901 drug may hold potential to prevent neurofibromatosis 1 in children

A drug originally developed to stop cancerous tumors may hold the potential to prevent abnormal brain cell growth and learning disabilities in some children, if they can be diagnosed early enough, a new animal study suggests.

31 Aug 2012

Enrollment complete in Arrowhead’s CALAA-01 phase 1b trial on solid tumors

Arrowhead Research Corporation, a targeted therapeutics company, today announced that, through its Calando Pharmaceuticals subsidiary, it has completed enrollment of a phase 1b clinical trial of CALAA-01, its RNAi therapeutic candidate targeting solid tumors. All patients participating in the trial have completed dosing with the exception of one patient who is still receiving treatment and will continue to be monitored.

31 Aug 2012

New antibacterial coating on surgical sutures effectively reduces infections

Responding to an urgent need for better antibacterial coatings on surgical sutures, scientists are reporting the discovery of a new coating that is almost 1,000 times more effective than the most widely used commercial coating.

31 Aug 2012

Ironwood receives FDA approval for Linzess to treat chronic idiopathic constipation, IBS

The U.S. Food and Drug Administration today approved Linzess (linaclotide) to treat chronic idiopathic constipation and to treat irritable bowel syndrome with constipation (IBS-C) in adults.

31 Aug 2012

Grb10 plays a crucial role in increasing muscle mass during development

Scientists have moved closer toward helping people grow big, strong muscles without needing to hit the weight room. Australian researchers have found that by blocking the function of a protein called Grb10 while mice were in the womb, they were considerably stronger and more muscular than their normal counterparts.

31 Aug 2012

Sosei’s QVA149 Phase III study on COPD meets primary endpoint

Sosei Group Corporation confirms the information released today by Novartis that results from the fifth QVA149 (indacaterol maleate / glycopyrronium bromide) Phase III study, SPARK, met its primary endpoint of a reduced rate of moderate-to-severe COPD exacerbations compared to glycopyrronium bromide.

31 Aug 2012

MGC Diagnostics third quarter total revenues increase 8% to $6.9 million

MGC Diagnostics Corporation, a global medical technology company, today reported financial results for the third quarter of fiscal year 2012, ended July 31, 2012.

31 Aug 2012

Roundup: Brown's pension plan no panacea for Calif.; Personhood amendment won't make Colo. ballot

Even by the most ambitious forecasts, the plan Gov. Jerry Brown and fellow Democrats are championing to contain government worker pensions in California could leave state taxpayers awash in debt to public employees.

31 Aug 2012

Early European TAVI registry data unveiled

The 1-month follow-up results of the Transcatheter Valve Treatment Sentinel Pilot Registry have provided data on factors associated with transcatheter aortic valve implantation, as well as short term outcomes, in Europe.

30 Aug 2012

Dabigatran exposure may RE-LY on genetics

Researchers have found that variants in the ABCB1 and CES1 genes are associated with increased dabigatran plasma levels in patients taking the oral anticoagulant.

30 Aug 2012

Optimal cutoffs for defining pain in multiple sclerosis

A US study has identified optimal cutoffs for the definition of pain among individuals with multiple sclerosis.

30 Aug 2012

Physical, verbal reminders could improve preoperative preparation

Patients may be unable to recall much of the preoperative information they are given by anesthesiologists, suggesting the need for reminders such as printed instructions, and telephone calls the night before their procedure is scheduled, says a US research team.

30 Aug 2012