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New research identifies key protein complex in cellular quality control

Anyone who's tried to neatly gather a fitted sheet can tell you: folding is hard. Get it wrong with your laundry and the result can be a crumpled, wrinkled mess of fabric, but when folding fails among the approximately 7,000 proteins with an origami-like complexity that regulate essential cellular functions, the result can lead to one of a multitude of serious diseases ranging from emphysema and cystic fibrosis to Alzheimer's disease.

12 Aug 2024

Study uncovers OLAH as key driver of fatal respiratory disease

Respiratory infections can be severe, even deadly, in some individuals, but not in others.

12 Aug 2024

New antibody treatment shows promise in preventing heart transplant rejection

A new study from scientists at Cincinnati Children's suggests there may be a way to further protect transplanted hearts from rejection by preparing the donor organ and the recipient with an anti-inflammatory antibody treatment before surgery occurs.

12 Aug 2024

New perspectives on targeting BRAF alterations in cancer

A new research perspective was published in Oncotarget's Volume 15 on July 16, 2024, entitled, "Targeting the multifaceted BRAF in cancer: New directions."

12 Aug 2024

Stretching and meditation ease nocturnal muscle cramps in cirrhosis patients

People suffering from cirrhosis may find some symptom relief from two accessible activities: stretching and meditation.

12 Aug 2024

New genomic predictors of relapse in childhood B-cell acute lymphoblastic leukemia uncovered

Scientists from St. Jude Children's Research Hospital, Seattle Children's and the Children's Oncology Group (COG) have identified novel genetic variations that influence relapse risk in children with standard risk B-cell acute lymphoblastic leukemia (SR B-ALL), the most common childhood cancer.

12 Aug 2024

Beyond neurons: Glial cells identified as key players in Alzheimer's disease

Memory loss, confusion, speech problems – Alzheimer's disease is the most common cause of dementia, affecting about 35 million people worldwide, and the number is growing.

12 Aug 2024

New breast cell atlas sheds light on genetic ancestry's role in cancer development

Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have completed the most extensive mapping of healthy breast cells to date.

12 Aug 2024

Childhood vaccinations save trillions in societal costs while preventing millions of illnesses and deaths

Routine childhood vaccinations among children born between 1994 and 2023 have prevented millions of illnesses and deaths in the U.S., saving $540 billion in direct costs and $2.7 trillion in societal costs.

12 Aug 2024

Howard Hughes Medical Institute announces $500 million to support AI-driven projects in life sciences

The Howard Hughes Medical Institute today announced AI@HHMI, a $500 million investment over the next 10 years to support artificial intelligence-driven projects in the life sciences.

12 Aug 2024

Record heat in 2023 linked to over 47,000 deaths in Europe, study finds

More than 47,000 people died in Europe as a result of high temperatures in 2023, the warmest year on record globally and the second warmest in Europe.

12 Aug 2024

Novel exosome-based drug delivery system for synergistic cancer treatment

Ovarian cancer is one of the most common malignancies in women worldwide. Unlike breast cancer, ovarian cancer lacks early diagnostic markers and does not show noticeable symptoms until cancer metastases, leading to a low survival rate for ovarian cancer patients.

12 Aug 2024

MUSC researchers uncover the surprising role of the dorsal peduncular nucleus in opioid addiction

Opioids, like the commonly prescribed pain reliever oxycodone, are known for being highly addictive. In 2022, nearly 85,000 people died from an opioid overdose in the U.S. according to the Centers for Disease control.

12 Aug 2024

Emory researchers offer a new perspective on the mechanism behind Alzheimer's disease

New findings out of Emory University are challenging existing theories about the origins of Alzheimer's, the leading cause of dementia in the elderly worldwide.

12 Aug 2024

Study reveals how light-activated macrophages increase their appetite for cancer cells

The body has a veritable army constantly on guard to keep us safe from microscopic threats from infections to cancer.

12 Aug 2024

Researchers uncover mechanism for storing and using visual knowledge in the brain

Our brain interprets visual information by combining what we see with what we already know. A study published in the journal Neuron by researchers at the Champalimaud Foundation, and supported by the CaixaResearch Health Call of the la Caixa Foundation, reveals a mechanism for learning and storing this existing knowledge about the world.

12 Aug 2024

Engineered NK cells with IL-21 show strong antitumor activity against glioblastoma

Natural killer (NK) cells engineered to express interleukin-21 (IL-21) demonstrated sustained antitumor activity against glioblastoma stem cell-like cells (GSCs) both in vitro and in vivo, according to new research from The University of Texas MD Anderson Cancer Center.

12 Aug 2024

Medical News

New research identifies key protein complex in cellular quality control

Study uncovers OLAH as key driver of fatal respiratory disease

New antibody treatment shows promise in preventing heart transplant rejection

New perspectives on targeting BRAF alterations in cancer

Stretching and meditation ease nocturnal muscle cramps in cirrhosis patients

New genomic predictors of relapse in childhood B-cell acute lymphoblastic leukemia uncovered

Beyond neurons: Glial cells identified as key players in Alzheimer's disease

New breast cell atlas sheds light on genetic ancestry's role in cancer development

Childhood vaccinations save trillions in societal costs while preventing millions of illnesses and deaths

Howard Hughes Medical Institute announces $500 million to support AI-driven projects in life sciences

Record heat in 2023 linked to over 47,000 deaths in Europe, study finds

Novel exosome-based drug delivery system for synergistic cancer treatment

MUSC researchers uncover the surprising role of the dorsal peduncular nucleus in opioid addiction

Emory researchers offer a new perspective on the mechanism behind Alzheimer's disease

Study reveals how light-activated macrophages increase their appetite for cancer cells

Researchers uncover mechanism for storing and using visual knowledge in the brain

Engineered NK cells with IL-21 show strong antitumor activity against glioblastoma

Comprehensive mental health coverage laws improve children's access to care, study reveals

Researchers call for Medicare to cover driving safety evaluations of at-risk, older adults

Researchers identify key genetic players in dopamine signaling using transparent worms With The Help Of A Tin...

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

Data management challenges in scientific research

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