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PIONEER software breaks down barriers in protein-protein interaction research

Scientists from Cleveland Clinic and Cornell University have designed a publicly-available software and web database to break down barriers to identifying key protein-protein interactions to treat with medication.

24 Oct 2024

CDC approves monovalent COVID-19 boosters for adults

Today, CDC's Director Rochelle P. Walensky, M.D., M.P.H., signed a decision memo allowing Novavax monovalent COVID-19 boosters for adults.

24 Oct 2024

Low-carb diet may improve beta-cell function in type 2 diabetes patients

This study shows a carbohydrate-restricted diet boosts β-cell function in type 2 diabetes, offering a sustainable approach to manage the disease effectively.

24 Oct 2024

Arthritis-style immunotherapy shows promise for heart failure

A study uncovers IL-1β signaling in cardiac fibrosis, highlighting distinct fibroblast populations and promising immunotherapy strategies for heart failure.

24 Oct 2024

Voters fret high medical bills are being ignored by presidential rivals

Tom Zawierucha, 58, a building services worker in New Jersey, wishes candidates would talk more about protecting older Americans from big medical bills.

24 Oct 2024

Secure computing enables collaborative cancer research

The research project Federated Secure Computing, funded by the Stifterverband, handles cancer patient data analysis in the European health data space across national borders without sharing any actual data, utilizing the modern cryptographic method - secure multiparty computation. The European research team includes scientists from LMU Munich, Germany, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Italy, and cryptography experts from Cybernetica, Estonia.

24 Oct 2024

Researchers identify mechanism of immune suppression in ovarian cancer

Weill Cornell Medicine researchers have discovered a mechanism that ovarian tumors use to cripple immune cells and impede their attack—blocking the energy supply T cells depend on. The study, published Oct. 23 in Nature, points toward a promising new immunotherapy approach for ovarian cancer, which is notoriously aggressive and hard to treat.

24 Oct 2024

Sleep deprivation in early life increases autism risk

Sleep deprivation in adults has long been proven to cause long-term mental and physical health issues, including, but not limited to, weakened immune systems, weight gain, depression, and increased risk of dementia.

24 Oct 2024

How your baby’s birth and environment can shape lifelong gut health

Early life factors, like birth mode and green environments, shape infant gut microbiota, with outdoor time becoming crucial in late infancy. Residential greenery impacts diversity only during early infancy.

24 Oct 2024

Innovative pain assessment tool receives $8 million funding

Pain assessment in medicine often relies on imprecise visual rating scales featuring smiling or crying faces, frustrating patients and physicians alike. Children's National Hospital researchers aim to change this with a new device designed to precisely measure pain, backed by an $8-million award from the Advanced Research Projects Agency for Health (ARPA-H) Sprint for Women's Health.

24 Oct 2024

Deletion of long non-coding RNA linked to rare neurodevelopmental disorder

When a gene produces too much protein, it can have devastating consequences on brain development and function. Patients with an overproduction of protein from the chromodomain helicase DNA binding (CHD2) gene can develop a rare and severe neurodevelopmental disorder that renders them wheelchair-bound, nonverbal and with profound intellectual delays.

24 Oct 2024

How dancing can supercharge your health after 55: Discover why ballroom beats the gym!

Dance programs improve older adults' physical and mental well-being, with ballroom and folk dance showing the most consistent benefits. More inclusive, theory-driven studies are needed to optimize outcomes.

24 Oct 2024

High-sensitivity wastewater surveillance correlates with COVID-19 infections

Wastewater surveillance has gained attention as an effective method for monitoring regional infection trends. In July 2024, the National Action Plan for Novel Influenza, etc. included the regular implementation of wastewater surveillance during normal times, with results to be published periodically in Japan.

24 Oct 2024

Tibetan women’s high-altitude adaptations drive greater reproductive success

Researchers uncover how specific genetic and cardiovascular traits give Tibetan women an edge in surviving and thriving at high altitudes, linking better oxygen delivery to more successful pregnancies.

23 Oct 2024

Deforestation drives a surge in malaria cases in the Amazon

Deforestation in the Brazilian Amazon is linked to a rise in malaria cases, with a 1% increase in deforestation leading to a 6.3% spike in cases the following month. This relationship is strongest in highly forested and indigenous areas.

23 Oct 2024

Repeated mRNA vaccinations enhance mucosal antibody production

During the COVID pandemic, many of us have received multiple mRNA vaccines. New work by researchers at the VIB-UGent Center for Inflammation Research, Ghent University, and University Hospital Ghent, among others, has found that such repeated vaccinations lead to the presence of mucosal antibodies, for example, inside the nose. Their work appears in Science Translational Medicine.

23 Oct 2024

New antibody platform targets evolving viruses

Scientists at the Icahn School of Medicine at Mount Sinai, in collaboration with colleagues in the field, have developed an innovative antibody platform aimed at tackling one of the greatest challenges in treating rapidly evolving viruses like SARS-CoV-2: their ability to mutate and evade existing vaccines and therapies.

23 Oct 2024

myeloMATCH program opens enrollment for acute myeloid leukemia and MDS

Four leading cancer research organizations in the United States and Canada announce the opening of patient enrollment to myeloMATCH, a unique portfolio of clinical trials to test precision medicine treatments for adults with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).

23 Oct 2024

HER2-postive breast cancer drugs show promise for bile duct cancer treatment

Drugs designed to target HER2-postive breast cancer could also benefit some patients with bile duct cancer, according to results of a patient trial to be presented on Thursday at the 36th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Barcelona, Spain.

23 Oct 2024