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Human Genome Sciences reports results of mapatumumab Phase 2 trial for multiple myeloma

Human Genome Sciences, Inc. today announced the results of its randomized Phase 2 trial of mapatumumab (HGS-ETR1) in combination with bortezomib (Velcade) in patients with advanced multiple myeloma.

9 Jun 2010

LUMEDX certified as official ACC-NCDR ICD Registry 2.0 software vendor

The American College of Cardiology has certified LUMEDX Corporation--the industry leader in integrated cardiovascular information systems and the number one provider of ACC software--as an official ACC-NCDR ICD Registry 2.0 software vendor. LUMEDX's Export to ICD Registry solution is the latest in a suite of software applications developed to address the growing need for impeccable, accessible cardiovascular data, streamlined clinical workflows and superior data management.

9 Jun 2010

Some commonly used drugs cause bone loss: New research

New research helps to explain why some commonly used drugs come with a serious downside: They up your odds of breaking a bone. The drugs in question, glucocorticoids (e.g. cortisone and prednisone) and the insulin sensitizer rosiglitazone work through entirely different mechanisms as therapies for inflammatory diseases and diabetes respectively, and two studies in the June issue of Cell Metabolism now show that they lead to bone loss in different ways too.

9 Jun 2010

Additional markers of risk for diabetic microvascular complications beyond Hemoglobin A1c needed

The "gold standard" diabetes test, Hemoglobin A1c (A1C), explains much less about the risk of cardiovascular complications in patients with diabetes than originally thought, according to an article in the June 9 issue of the Journal of the American Medical Association (JAMA). The article entitled, "Beyond HbA1c: Need for Additional Markers of Risk for Diabetic Microvascular Complications," was co-authored by Irl Hirsch, M.D., of the University of Washington Medical School (Seattle, WA) and Michael Brownlee, M.D., of the Albert Einstein College of Medicine.

9 Jun 2010

Delaware's first-in-the-nation guidelines for nutrition and physical activity in child care accepted: Study

A study conducted by the nonprofit health research organization Altarum Institute suggests that Delaware's first-in-the-nation guidelines for nutrition and physical activity in child care are broadly accepted by both child care providers and parents, and that challenges to implementing the policies can be overcome with support.

9 Jun 2010

Four-year follow-up results from SPRYCEL Phase 3 study in CML-CP presented at ASCO

Bristol-Myers Squibb Company and Otsuka Pharmaceutical Co., Ltd. today announced four-year follow-up results from a Phase 3 randomized, open-label, dose-optimization study of SPRYCEL® (dasatinib) in chronic-phase chronic myeloid leukemia (CML-CP) patients resistant or intolerant to Gleevec®* (imatinib mesylate). At four years, for all patients administered SPRYCEL 100 mg once daily, overall survival was 82% (95% CI: 76%-88%) and progression-free survival was 66% (95% CI: 57%-74%).

9 Jun 2010

Stress-reducing psychological intervention helps increase quality of life among women with breast cancer

Stress-reducing psychological intervention helps to increase survival and quality of life among women with recurrent breast cancer over the long-term, according to results of a Phase III study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

9 Jun 2010

Lapses in infection control common in ambulatory surgical centers

An assessment of nearly 70 ambulatory surgical centers in three states found that lapses in infection control were common, including for practices such as hand hygiene, injection and medication safety and equipment reprocessing, according to a study in the June 9 issue of JAMA.

9 Jun 2010

Patients with BAI can be managed non-operatively with beta-blockade: Researchers

Select patients with blunt aortic injury can be safely managed non-operatively with beta-blockade to lower the heart rate and blood pressure, according to a new study from the 64th Vascular Annual Meeting presented by the Society for Vascular Surgery.

9 Jun 2010

Cycle helmets exude odoriferous oils when cracked

Cycle helmets are available in a wide range of types, including foldable models, models fitted with a flashing rear light or featuring an iPhone display. In future, they will start to smell distinctively if they need to be replaced. A new process causes odoriferous oils to exude from plastic materials if they are cracked.

9 Jun 2010

Purdue University researchers develop potential new tool for medical diagnostics, testing food

Researchers at Purdue University have developed a potential new tool for medical diagnostics, testing food and water for contamination, and crime-scene forensics.

9 Jun 2010

Clinical guidelines for UC emergency medicine physicians

Though guidelines for best treatment practices are common, they are only partially effective without standardized, routine exposure to them in clinical practice, according to a study conducted by University of Cincinnati emergency medicine researchers.

9 Jun 2010

Biofeedback training on MPA decreases performance anxiety, improves performance in musicians

Traditionally, the most successful methods used to combat stage fright have been prescribed medications (beta blockers) and aerobic exercise. In the most recent issue of Biofeedback, researchers studied another technique: the effect of biofeedback training on Musical Performance Anxiety (MPA). MPA is a severe form of stage fright marked by high anxiety levels and impaired performance.

9 Jun 2010

Researchers compare effectiveness of IB and AMP in high-risk patients

Major amputation is often selected over infrainguinal bypass in patients with severe systemic comorbidities because of a presumed decrease in risk of perioperative morbidity and mortality. To investigate this presumption, researchers from the Division of Vascular and Endovascular Surgery at the Brigham and Women's Hospital in Boston undertook a risk-adjusted comparison of early postoperative morbidity and mortality of high-risk patients undergoing infrainguinal bypass and major amputation.

9 Jun 2010

Tumors not likely to worsen during active surveillance period in low risk prostate cancer patients

Johns Hopkins experts have found that men enrolled in an active surveillance program for prostate cancer that eventually needed surgery to remove their prostates fared just as well as men who opted to remove the gland immediately, except if a follow-up biopsy during surveillance showed high-grade cancer.

9 Jun 2010

Impax reaches agreement with Endo and Penwest to settle pending litigation for OPANA ER

Impax Laboratories, Inc. today announced that it has reached agreement with Endo Pharmaceuticals and Penwest Pharmaceuticals to settle pending U.S. litigation with regard to the production and sale of generic formulations of OPANA ER (oxymorphone hydrochloride) Extended Release tablets.

9 Jun 2010

Research shows excessive daytime sleepiness increases depression symptoms among high school seniors

High school seniors with excessive daytime sleepiness have an elevated risk for depression, suggests a research abstract that will be presented Wednesday, June 9, 2010, in San Antonio, Texas, at SLEEP 2010, the 24th annual meeting of the Associated Professional Sleep Societies LLC.

9 Jun 2010

Screen time contributes to headache, backache in school-aged teenagers

The amount of time teenagers spend in front of TV screens and monitors has been associated with physical complaints. A large study of more than 30,000 Nordic teenagers published in the open access journal BMC Public Health has shown that TV viewing, computer use and computer gaming (screen time) were consistently associated with back pain and recurrent headaches.

9 Jun 2010

Graphic anti-tobacco messages lower intentions to smoke among youth: Research

Straight from the longstanding tobacco industry playbook which calls for trying to litigate effective public education programs out of existence, three major tobacco companies – Philip Morris, RJ Reynolds and Lorillard – filed suit last week to block the New York City Board of Health's requirement that retail outlets post hard-hitting anti-tobacco posters where tobacco products are sold.

9 Jun 2010

MRG's 2010 report on European markets for heart valve devices

According to Millennium Research Group (MRG), the global authority on medical technology market intelligence, national registry data presented at last month's euroPCR will drive adoption of transcatheter aortic valve implantation, as illustrated in MRG's new European Markets for Heart Valve Devices 2010 report. Presented by European physicians at the Paris conference, the encouraging registry results revealed high success rates in addition to acceptable mortality rates and complications in the high-risk patient population considered in the registries.

9 Jun 2010

Medical News

Human Genome Sciences reports results of mapatumumab Phase 2 trial for multiple myeloma

LUMEDX certified as official ACC-NCDR ICD Registry 2.0 software vendor

Some commonly used drugs cause bone loss: New research

Additional markers of risk for diabetic microvascular complications beyond Hemoglobin A1c needed

Delaware's first-in-the-nation guidelines for nutrition and physical activity in child care accepted: Study

Four-year follow-up results from SPRYCEL Phase 3 study in CML-CP presented at ASCO

Stress-reducing psychological intervention helps increase quality of life among women with breast cancer

Lapses in infection control common in ambulatory surgical centers

Patients with BAI can be managed non-operatively with beta-blockade: Researchers

Cycle helmets exude odoriferous oils when cracked

Purdue University researchers develop potential new tool for medical diagnostics, testing food

Clinical guidelines for UC emergency medicine physicians

Biofeedback training on MPA decreases performance anxiety, improves performance in musicians

Researchers compare effectiveness of IB and AMP in high-risk patients

Tumors not likely to worsen during active surveillance period in low risk prostate cancer patients

Impax reaches agreement with Endo and Penwest to settle pending litigation for OPANA ER

Research shows excessive daytime sleepiness increases depression symptoms among high school seniors

Screen time contributes to headache, backache in school-aged teenagers

Graphic anti-tobacco messages lower intentions to smoke among youth: Research

MRG's 2010 report on European markets for heart valve devices

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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