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Historic DNA analysis identifies Down and Edwards syndromes in ancient humans

By analyzing ancient DNA, an international team of researchers have uncovered cases of chromosomal disorders, including what could be the first case of Edwards syndrome ever identified from prehistoric remains.

20 Feb 2024

Aging alters fibroblasts to promote pancreatic cancer growth

Older people may be at greater risk of developing pancreatic cancer and have poorer prognoses because of age-related changes in cells in the pancreas called fibroblasts, according to research led by investigators from the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins Bloomberg School of Public Health and the Bloomberg~Kimmel Institute for Cancer Immunotherapy.

20 Feb 2024

Study reveals novel mechanism for longevity of oocytes

Oocytes are immature egg cells that develop in almost all female mammals before birth. The propagation of future generations depends on this finite reserve of cells surviving for many years without incurring damage.

20 Feb 2024

Graphene biosensor offers accurate assessment of meat freshness

The freshness of animal meat is an essential property determining its quality and safety. With advanced technology capable of preserving food for extended periods of time, meat can be shipped around the globe and consumed long after an animal dies.

20 Feb 2024

Study evaluates colorectal cancer screening programs in Latin America

Little is known about colorectal cancer screening strategies throughout the Western Hemisphere, with the exception of the U.S. and Canada.

20 Feb 2024

Ultra-processed foods: A growing threat to public health

From fizzy drinks to cereals and packaged snacks to processed meat, ultra-processed foods are packed with additives.

20 Feb 2024

Study reveals low utilization of PCSK9 inhibitors in high-risk patients

A new study published in Circulation: Cardiovascular Quality and Outcomes from the Family Heart Foundation - a patient-centered research and advocacy nonprofit organization dedicated to improving the lives of families impacted by inherited lipid disorders and LDL-cholesterol - revealed that utilization of proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9i) to reduce low-density lipoprotein cholesterol (LDL-C) remains low among high-risk patients.

20 Feb 2024

Novel genetic locations associated with primary open-angle glaucoma identified

An international genetic study using multiancestry biobanks has identified novel genetic locations associated with primary open-angle glaucoma (POAG), the most common type of glaucoma and the leading cause of irreversible blindness globally.

20 Feb 2024

Study shows favorable response to app-based cancer pain management for children

A recent study led by Assistant Professor Lindsay Jibb of the Lawrence Bloomberg Faculty of Nursing and Scientist at The Hospital for Sick Children (SickKids) found that parents of young children with cancer, along with pediatric cancer clinicians are in favor of an app-based solution that Jibb and her team are creating, to help parents manage their child's cancer pain at home.

20 Feb 2024

Early puberty in first-born daughters linked to prenatal stress in their mothers

A UCLA-led team of researchers has found a correlation between early signs of adrenal puberty in first-born daughters and their mothers' having experienced high levels of prenatal stress.

20 Feb 2024

Ultrahigh-spatial-resolution PCD-CT improves assessment of coronary artery disease

Ultrahigh-spatial-resolution photon-counting detector CT improved assessment of coronary artery disease (CAD), allowing for reclassification to a lower disease category in 54% of patients, according to a new study published today in Radiology, a journal of the Radiological Society of North America.

20 Feb 2024

Annual breast cancer screening beginning at age 40 results in highest mortality reduction

Annual breast cancer screening beginning at age 40 and continuing to at least age 79 results in the highest reduction in mortality with minimal risks, according to a new study published today in Radiology, a journal of the Radiological Society of North America.

20 Feb 2024

Investigating dosage in hyperbaric oxygen therapy for post-covid conditions

Hyperbaric oxygen therapy, giving patients 100 percent oxygen at a pressure corresponding to 10-20 meters below sea level, has been around for almost 100 years.

20 Feb 2024

Novel therapy harnesses stem cell-derived exosomes for diabetic wound healing

Researchers unveiled a novel therapy for diabetic wound healing. This research highlights the use of exosomal miR-4645-5p from hypoxic bone marrow mesenchymal stem cells (BMSCs) to significantly enhance wound healing by promoting keratinocyte autophagy.

20 Feb 2024

Study reveals racial disparities in access to buprenorphine for opioid use disorder

Buprenorphine, a life-saving medication for opioid use disorder, is far less accessible in geographic areas of the United States with racially and ethnically diverse populations than in predominantly white areas, according to a new study of pre-pandemic data led by health policy scientists at the University of Pittsburgh School of Public Health published today in Journal of Addiction Medicine.

20 Feb 2024

Study proposes novel approach to slow neuromuscular degeneration in ALS patients

A study led by the Center for Biomaterials and Tissue Engineering of the Universitat Politècnica de València, member of Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine, in collaboration with the Instituto de Investigación Sanitaria La Fe and the University of Zaragoza proposes a novel approach to slow neuromuscular degeneration in patients with Amyotrophic Lateral Sclerosis.

20 Feb 2024

New model pinpoints drug interactions in the digestive tract

Any drug that is taken orally must pass through the lining of the digestive tract. Transporter proteins found on cells that line the GI tract help with this process, but for many drugs, it's unknown which of those transporters they use to exit the digestive tract.

20 Feb 2024