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Bariatric surgery shows potential for resolving type 2 diabetes

As the incidence of obesity-induced type 2 diabetes mellitus continues to increase worldwide, medical research indicates that surgery to reduce obesity can completely eliminate all manifestations of diabetes.

2 Apr 2009

Discovery of gene that modifies severity of cystic fibrosis lung disease

Researchers at Wake Forest University Baptist Medical Center, and colleagues, have identified a gene that modifies the severity of lung disease in people with cystic fibrosis, a lethal genetic condition.

2 Apr 2009

Scientists detect molecular obesity link to insulin resistance, type II diabetes

A molecular switch found in the fat tissue of obese mice is a critical factor in the development of insulin resistance, report scientists at the Salk Institute for Biological Studies.

2 Apr 2009

Schizophrenia could be caused by faulty signalling in the brain

In the biggest study of its kind, scientists looking in detail at brain samples donated by people with the condition have identified 49 genes that work differently in the brains of schizophrenia patients compared to controls.

2 Apr 2009

'Pre-diabetics' face heightened risk of heart disease

The study, published in the Journal of Clinical Endocrinology & Metabolism , was led by Jill P. Crandall, M.D., associate professor of clinical medicine and director of the Diabetes Clinical Trials Unit at Einstein.

2 Apr 2009

Study looks at long-term benefits of the Wingspan stent

Rush University Medical Center is participating in a National Institutes of Health (NIH) study to determine the best course of treatment to reduce the risk of stroke patients suffering another stroke.

2 Apr 2009

The effects of warning smokers on perceived risk, worry and motivation to quit

Go ahead. Nag, nag, nag. It might do some good after all. The more smokers worry about health risks, the more they will contemplate quitting, according to a new study in the latest issue of the journal Annals of Behavioral Medicine.

2 Apr 2009

Opioid antagonists show potential for problematic pain

Achieving effective, durable, and safe pain relief, especially in patients with chronic and/or severe pain conditions, can be difficult.

2 Apr 2009

Molecular test for cancer relapse in UK children

A molecular marker used in America to predict whether children with a form of kidney cancer, called Wilms' tumour, are more likely to relapse than other children, could be useful for UK patients.

2 Apr 2009

Moderate alcohol intake may be beneficial to bone health

In an epidemiological study of men and post-menopausal women primarily over 60 years of age, regular moderate alcohol intake was associated with greater bone mineral density (BMD).

2 Apr 2009

Missing link between fructose, insulin resistance found

A new study in mice sheds light on the insulin resistance that can come from diets loaded with high-fructose corn syrup, a sweetener found in most sodas and many other processed foods.

2 Apr 2009

Is telmisartan effective in treating non-alcoholic steatohepatitis?

Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are well-recognized causes of progressive liver disease leading to cirrhosis and hepatocellular carcinoma.

2 Apr 2009

Is esomeprazole the best choice for reflux esophagitis patients?

In patients with gastroesophageal reflux disease (GERD), esomeprazole, has demonstrated pharmacological and clinical benefits beyond those seen with the other proton pump inhibitors (PPIs).

2 Apr 2009

Eating a low energy density diet can offset influence of obesity gene

Children who carry a gene strongly associated with obesity could offset its effect by eating a low energy density diet, according to new research from UCL (University College London) and the University of Bristol published in PLoS ONE.

2 Apr 2009

Multiple childhood maltreatments lead to underage binge drinking

Researchers from Boston University found that multiple types of child maltreatment are robust risk factors for underage binge drinking based on a national multi-year study that explored the influence of social environment on the health of adolescents.

2 Apr 2009

Inactivity of proteins behind longer shelf life when freezing

Frozen biological material, for example food, can be kept for a long time without perishing.

2 Apr 2009

High novelty-seeking and low avoidance of harm contribute to alcohol dependence

Personality factors can influence the development of alcohol dependence (AD).

2 Apr 2009

Two or more alcoholic drinks a day may increase pancreatic cancer risk

Men and women who consume two or more alcoholic drinks a day could increase their risk of developing pancreatic cancer, according to a study published in Cancer Epidemiology, Biomarkers and Prevention , a journal of the American Association for Cancer Research.

2 Apr 2009

FDA warning letter to Genzyme related to the Allston facility

BioMarin Pharmaceutical Inc. has announced that the FDA warning letter issued to Genzyme addressing deficiencies related to Genzyme's Allston Landing manufacturing facility during an inspection performed in September and October 2008 has no foreseeable impact on the supply of Aldurazyme.

2 Apr 2009

FDA provides positive review of InNexus Biotechnology development plan for lead preclinical candidate

InNexus Biotechnology Inc. has announced the United States Food & Drug Administration (FDA) has completed its comprehensive review of the development plans for InNexus' lead preclinical candidate, DXL625 (CD20) for the prospective treatment of Non-Hodgkin's Lymphoma (NHL) and/or Chronic Lymphocytic Leukemia (CLL).

2 Apr 2009