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Plasminogen activator inhibitor type-1 -- a potential link between heart failure and diabetes

Researchers at the University of Vermont Cardiovascular Research Institute, Colchester, Vermont have found that increased expression in the heart of plasminogen activator inhibitor type-1 (PAI-1) is profibrotic.

24 Feb 2009

Physical fitness improves spatial memory, increases size of hippocampi

When it comes to the hippocampus, a brain structure vital to certain types of memory, size matters.

24 Feb 2009

McGill researcher's radical new green chemistry makes the impossible possible

McGill University chemistry professor Chao-Jun (C.J.) Li is known as one of the world leading pioneers in green chemistry, an entirely new approach to the science which eschews the use of toxic, petrochemical-based solvents in favour of basic substances like water and new ways of making molecules.

24 Feb 2009

New report reveals serious flaws in abstinence programs

As Congress and states reconsider funding for abstinence-only programs, the largest study ever of what is taught in sexuality education classes reveals that abstinence programs are plagued with factual errors, use shame and fear to teach about sexuality and actively discourage the use of condoms to protect against pregnancy and sexually transmitted diseases.

24 Feb 2009

Investigational protein may reverse neurodegenerative diseases

An investigational protein that transformed normal laboratory mice into super-jocks holds great promise in developing new treatments for neurodegenerative diseases like Parkinson's, Alzheimer's and ALS (Lou Gehrig's Disease), say researchers at the University of Virginia Health System.

24 Feb 2009

Exploring the roles of noise in the eukaryotic cell cycle

A single cell - whether a yeast cell or one of your cells - is exquisitely sensitive to its surroundings.

24 Feb 2009

Mount Sinai first in US to implant FDA-cleared ring for mitral valve repair

David H. Adams, MD, Marie-Josée and Henry R. Kravis Professor and Chairman of the Department of Cardiothoracic Surgery at The Mount Sinai Medical Center, performed the first two implantations of the Carpentier-Edwards Physio II ring in the United States yesterday.

24 Feb 2009

Mindset BioPharmaceuticals receives notice of allowance for European patent related to insulin sensitizers in dementia and memory loss

Mindset BioPharmaceuticals (USA) Inc ("MINDSET") a company privately held by MPM Capital and other shareholders announced today that it has received a Notice of Allowance in Europe related to patent applications describing the use of insulin sensitizer drugs for the prevention and treatment of memory loss.

24 Feb 2009

Low to moderate alcohol consumption among women associated with increased cancer risk

Low to moderate alcohol consumption among women is associated with a statistically significant increase in cancer risk and may account for nearly 13 percent of the cancers of the breast, liver, rectum, and upper aero-digestive tract combined, according to a report in the February 24 online issue of the Journal of the National Cancer Institute.

24 Feb 2009

Mental fatigue impairs physical performance in humans

When participants performed a mentally fatiguing task prior to a difficult exercise test, they reached exhaustion more quickly than when they did the same exercise when mentally rested, a new study finds.

24 Feb 2009

Living wills have an impact on pre-hospital lifesaving care

A new study conducted at the Hamot Medical Center in Erie, Pennsylvania, and published by Elsevier in the February 2009 issue of The Journal of Emergency Medicine shows that there is a lack of education and understanding in what sets a living will in motion in a pre-hospital setting. Education and implementation of code status designations can clarify this confusion.

24 Feb 2009

Putting a face on influenza

Influenza results in billions of dollars in lost wages every year, and recent studies found that an estimated 75 million missed workdays a year, and about 200 million days of restricted activity, are due to this vaccine-preventable disease.

24 Feb 2009

Having health insurance essential for people's health and well-being

The evidence shows more clearly than ever that having health insurance is essential for people's health and well-being, and safety-net services are not enough to prevent avoidable illness, worse health outcomes, and premature death, says a new report from the Institute of Medicine.

24 Feb 2009

Guidelines for treating patients with cardiovascular disease often based on weaker evidence

An examination of clinical practice guidelines for treating cardiovascular disease finds that current recommendations are largely based on lower levels of evidence or expert opinion, according to a study in the February 25 issue of JAMA, the Journal of the American Medical Association.

24 Feb 2009

Goserelin improves long-term survival in premenopausal women with early breast cancer

Goserelin, a lutenizing hormone-releasing hormone agonist, reduces the long-term risk of disease recurrence and deaths in premenopausal women with early breast cancer who did not take tamoxifen, according to trial data reported in the February 24 online issue of the Journal of the National Cancer Institute.

24 Feb 2009

Diabetes a risk factor for postpartum depression

Postpartum depression is a serious - and often undiagnosed - condition affecting about 10 to 12 percent of new mothers.

24 Feb 2009

Determining risk for pancreatic cancer

In the latest clinical trial for a technique to detect pancreatic cancer, researchers found they could differentiate cells that are cancerous from those that are benign, pre-cancerous, or even early stage indicators called mucinous cystic lesions.

24 Feb 2009

Children with hypertension have trouble with goal-directed tasks

Children with high blood pressure are not as good at complicated, goal-directed tasks, have more working memory problems and are not as adept at planning as their peers without hypertension, according to recent research.

24 Feb 2009

Bone Biologics issued U.S. patent for recombinant protein process

Bone Biologics Inc. has announced that it has received a US Patent Office Notice of Allowance of patent claims which protect a method of production for the UCB-1 (NELL-1) recombinant protein that Bone Biologics uses in the bone repair/regeneration technology in its lead product.

24 Feb 2009

Ambrx and Merck Serono expand collaboration through multiple sclerosis drug

Ambrx Inc, and Merck Serono have announced a global strategic collaboration to develop and commercialize Ambrx's ARX424 preclinical product candidate for the treatment of multiple sclerosis.

24 Feb 2009