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Xencor and CSL Limited establish antibody optimization collaboration

Xencor, Inc., an antibody discovery and development company, announced today that it has entered into an antibody optimization collaboration with CSL, Ltd. The collaboration will provide CSL with access to Xencor's XmAb technology platform to enhance the ADCC effector function of its therapeutic antibodies.

23 Feb 2009

Vitamin D may help fight common colds

Vitamin D may be an important way to arm the immune system against disorders like the common cold, report investigators from the University of Colorado Denver (UC Denver) School of Medicine, Massachusetts General Hospital (MGH) and Children's Hospital Boston.

23 Feb 2009

Vitamins B6 and B12 plus folic acid may reduce risk of age-related macular degeneration in women

Taking a combination of vitamins B6 and B12 and folic acid appears to decrease the risk of age-related macular degeneration in women, according to a report in the February 23 issue of Archives of Internal Medicine , one of the JAMA/Archives journals.

23 Feb 2009

Breakthrough in human papillomavirus research

UAB (University of Alabama at Birmingham) researchers have developed a new, inexpensive and efficient method for producing and studying a type of human papillomavirus (HPV) that causes cervical cancer.

23 Feb 2009

Hormone disorder drug cabergoline could help drinkers stay sober

A drug prescribed for male and female infertility and menstrual disorders could hold the key to a more effective treatment for alcoholism, according to a study by researchers at the UCSF-affiliated Ernest Gallo Clinic and Research Center.

23 Feb 2009

Scientists manipulate bacteria into generating their own vaccine

Scientists have developed a way to manipulate bacteria so they will grow mutant sugar molecules on their cell surfaces that could be used against them as the key component in potent vaccines.

23 Feb 2009

Take 2: What protein and where it is located are important for drug design

Drugs that target a single signaling pathway that drives tumor development and/or progression have been developed successfully to treat a few forms of cancer.

23 Feb 2009

Internet addiction linked to aggression in teenagers

Armed with the findings of a new study, Taiwanese researchers suggest parents and educators pay more attention to children's online habits because Internet-addicted teens seem more prone to aggression.

23 Feb 2009

SYNTAX defines borders between CABG and PCI with TAXUS drug-eluting stents

Coronary artery bypass grafting (CABG) should remain the "standard of care" for patients with complex coronary artery disease, concludes the SYNTAX study, published in the New England Journal of Medicine (online February 18, 2009, Print edition March 5).

23 Feb 2009

Stanford/Packard researchers recruit children for study of the biology of autism

Scientists have put forward many theories about why children with autism struggle to communicate with other people, but they have yet to find definitive answers.

23 Feb 2009

Screening cuts cervical cancer rates by half

In the wake of Jade Goody's tragic story, the latest Cancer Research UK statistics reveal that there is hope on the horizon for cervical cancer.

23 Feb 2009

Scientists identify lab-made proteins that neutralize a broad range of influenza A viruses

Scientists have identified a small family of lab-made proteins that neutralize a broad range of influenza A viruses, including the H5N1 avian virus, the 1918 pandemic influenza virus and seasonal H1N1 flu viruses.

23 Feb 2009

Significant Rett syndrome discovery

A paper published online today in Nature Neuroscience reveals the presence of methyl CpG binding protein 2 (MeCP2) in glia. MeCP2 is a protein associated with a variety of neurological disorders, including Rett Syndrome, the most physically disabling of the autism spectrum disorders.

23 Feb 2009

Patient knowledge of health information influences cancer treatment

A new analysis finds that when colorectal cancer patients seek out health information from the internet and news media, they are more likely to be aware of and receive the latest treatments for their disease.

23 Feb 2009

Why we turn gray

A team of European scientists have finally solved a mystery that has perplexed humans throughout the ages: why we turn gray.

23 Feb 2009

New technique to determine tumor methylation status

Current research suggests that a new technique to determine tumor methylation status can be used in archived tissue samples.

23 Feb 2009

Mechanisms that prevent Alzheimer's Disease: Enzymatic activity plays key role

In a project involving the collaboration of several institutes, research scientists of the Johannes Gutenberg University Mainz have succeeded in gaining further insight in the functioning of endogenous mechanisms that protect against the development of Alzheimer's disease.

23 Feb 2009