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Lay people can effectively use defibrillators to save the lives of cardiac arrest victims

The first large-scale study to see whether trained volunteers and lay people can use defibrillators to save the lives of cardiac arrest (CA) victims has concluded that their use by lay people is safe, and if the response time can be shortened to within eight minutes there is the potential to save the lives of 15 out of 100 people who collapse suddenly with CA.

5 Dec 2005

Liver transplants may not be suitable for all cystic fibrosis patients

A new study on patients with cystic fibrosis (CF) who have had abnormal bleeding from ruptured blood vessels in the esophagus (variceal hemorrhage) as a result of liver disease found that transplant may not be indicated if there are no other indications of advanced liver disease.

5 Dec 2005

Phenoxodiol - docetaxel combination for women with recurrent ovarian cancer

A clinical study of ovarian cancer initiated by investigators at Yale School of Medicine will combine the anti-cancer drug phenoxodiol with docetaxel for women with recurrent ovarian cancer.

5 Dec 2005

Redefining how the heart functions

Redefining how the heart functions is one of the first steps that could lead to revolutionary approaches to treating patients who have heart failure - 5 million and growing in the U.S. - or better yet, preventing the heart failure from developing

5 Dec 2005

First study to demonstrate the elimination of a racial/ethnic disparity in health and healthcare

Community-based case managers are much more effective than traditional government outreach and enrollment programs in obtaining insurance coverage for uninsured Latino children, according to a study authored by a physician at the Medical College of Wisconsin in Milwaukee, and Children's Hospital of Wisconsin.

5 Dec 2005

Men are from Mars, women are from Venus - when it comes to brains!

The comedians are right. The science proves it. A man's brain and a woman's brain really do work differently.

5 Dec 2005

Researchers link microRNA - miR 196 - to limb development

A tiny strand of molecules plays a role in how our arms and legs develop and grow - a finding that sheds light on perplexing bits of material once dismissed as genetic "junk," say scientists at the University of Florida and Harvard University.

5 Dec 2005

Researchers move in on novel therapeutics to inhibit melanoma

Northwestern University researchers have developed a novel, three-dimensional model that allows scientists to observe how interacting with the microenvironment of metastatic melanoma cells induces normal skin cells to become similar to aggressive cancer cells that migrate and spread throughout the body.

5 Dec 2005

Sleep-disorders related to breathing suggest increase risk of stroke

Individuals who experience moderate to severe sleep-disordered breathing are four times more likely to have a stroke during the next four years than those who do not suffer from the problem.

5 Dec 2005

Researchers detail mechanism of stroke

In the neural train wreck that is stroke, the cutoff of oxygen kills brain cells through a buildup of acid, as well as by overexciting receptors on the surface of brain cells.

5 Dec 2005

Inexpensive blood test for major parasitic diseases

The National Reference Centre for Parasitology (NRCP), based at the MUHC, is developing a comprehensive and inexpensive blood safety test that will allow clinicians to check for all major parasitic diseases in patients' blood.

5 Dec 2005

Twins, triplets have greater chance of birth defects

Twins, triplets and other multiples have a nearly 50 percent greater chance of being born with birth defects, and boys tend to be more at risk than girls, according to two population-based studies conducted at the University of Florida.

5 Dec 2005

Unexpected link between muscular dystrophy and muscle wasting associated with cancer

A new study provides important insight into the mechanisms of a muscle wasting disorder that interferes with treatment for cancer and has a negative impact on patient survival.

5 Dec 2005

HRAS mutation analysis in Costello Syndrome

Gene mutations in the HRAS sequence are present in most patients affected with Costello syndrome, according to a new study in the American Journal of Medical Genetics. The mutations occurred de novo in patients, meaning, they were not observed in their parents' genes.

5 Dec 2005

CFH Y402H confers similar risk of soft drusen and both forms of advanced AMD

Gene is associated with increased risk of precursor of macular degeneration A variant in a gene called Complement Factor H (CFH) appears to contribute to the increased risk of advanced age-related macular degeneration (AMD) largely or entirely through its impact on the development of a precursor of advanced AMD called soft drusen (small yellowish, extracellular deposits of lipid, protein and cellular debris in the back of the eye), according to a multinational team of researchers.

2 Dec 2005

Discovery of genetic mechanism that causes new arteries to grow in response to blocked arteries

Researchers at the San Francisco VA Medical Center have uncovered part of the genetic mechanism that causes new arteries to grow in response to blocked arteries.

2 Dec 2005

Overproduction of food in rich countries is fuelling health problems worldwide

The dairy sector in the European Union is an example of how agriculture subsidies can lead to negative health effects in Europe as well as in developing countries.

2 Dec 2005

Fast-tracked screening for Chlamydia in UK

Young women asking for the morning-after pill at pharmacies will be offered fast-tracked screening for Chlamydia, the UK's most common sexually transmitted infection, in a University of Manchester study.

From The University of Manchester 2 Dec 2005

Findings may help in development of new anti-inflammatory compounds

Virginia Commonwealth University researchers studying the enzyme that triggers inflammation have found that it may be a target for a new class of anti-inflammatory drugs to treat arthritis, asthma, multiple sclerosis, lung and colon cancers and Alzheimer's disease.

2 Dec 2005

Making angioplasty safer

When life-threatening problems occur during angioplasty procedures, doctors may perform emergency coronary artery bypass graft surgery, but data from the Mayo Clinic indicates that need to send patients to emergency surgery has dropped sharply, according to a new study in the Dec. 6, 2005, issue of the Journal of the American College of Cardiology.

2 Dec 2005