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FDA Critical Path Initiative addresses differences between women's and men's health outcomes

Advanced medical technology and analysis methods now being promoted through the Food and Drug Administration's Critical Path Initiative to facilitate the development of drugs, biologics and devices can help address differences between women and men in the detection and treatment of disease, according to a paper published in the Winter 2007 issue of Drug Discovery Today: Technologies.

20 Dec 2007

Study looks at prevalence of "false-positive" catheterization laboratory activation for patients with suspected STEMI

Physicians caring for patients suspected of having a heart attack may trigger "false-positive" activation of the cardiac catheterization laboratory based on test results suggestive of a heart attack, according to a study in the December 19 issue of JAMA: The Journal of the American Medical Association.

20 Dec 2007

Early surgical treatment contributes to better outcomes in gallstone pancreatitis cases

Although delaying surgical treatment remains the standard of care for patients with severe gallstone pancreatitis, a new study published in the December issue of the Journal of the American College of Surgeons shows that, contrary to widespread belief, early cholecystectomy -- or surgical removal of the gallbladder -- significantly reduces hospital stays in patients with mild to moderate gallstone pancreatitis with no increase in complications or mortality.

20 Dec 2007

Dolphin therapy - a lose-lose situation for people and dolphins

People suffering from chronic mental or physical disabilities should not resort to a dolphin "healing" experience, warn two researchers from Emory University.

20 Dec 2007

Does treating worms in people with HIV slow progression to AIDS?

Of the 25 million people infected with HIV-1 in Africa, as many as half are thought to be co-infected with worms (helminths), and there is evidence that these worms may result in a more rapid progression of HIV infection to AIDS.

20 Dec 2007

Creative and challenging work helps people stay healthy

Employees who have more control over their daily activities and do challenging work they enjoy are likely to be in better health, according to a new study from The University of Texas at Austin published in this month's Journal of Health and Social Behavior.

20 Dec 2007

Colon cancer screenings may bring little benefit and may actually pose harm

Even though current guidelines advocate colorectal cancer screenings for those with severe illnesses, they may bring little benefit and may actually pose harm, according to a recent study by Yale School of Medicine researchers published in the Archives of Internal Medicine.

20 Dec 2007

Childhood exposure to disadvantaged neighborhoods negatively affects verbal ability

Childhood exposure to severely disadvantaged communities is linked to decreased verbal ability later in childhood, a lasting negative effect that continues even after moving out of the neighborhood, according to research that will be published this week in the Proceedings of the National Academy of Sciences.

20 Dec 2007

Rituximab may be promising treatment for diabetes

An antibody used to treat certain cancers and rheumatoid arthritis appears to greatly delay type 1 diabetes in mice, Yale School of Medicine researchers report in the Journal of Clinical Investigation.

20 Dec 2007

Built-in exercise monitor predicts fitness

We all hold the secret to getting fit, according to researchers from the University of Exeter. The research team has shown that we each have a built-in ability to judge how hard our bodies are working, often with remarkable precision.

20 Dec 2007

Brains respond differently to thirst depending upon age

Twelve healthy subjects in their 60s and 70s showed a different pattern of brain activations during thirst and satiation than did 10 healthy subjects in their 20s who drank the same amounts and underwent imaging with positron-emission tomography (PET).

20 Dec 2007

War veterans with brain injuries show a faster decline in cognitive functioning as they age

A study of Vietnam war veterans who suffered brain injuries during the conflict has found that the men show a faster decline in their cognitive functioning as they grow older than veterans without such injuries.

20 Dec 2007

BMI criteria for obesity surgery should be lowered

UT Southwestern Medical Center researchers have found that the existing body mass index criteria for obesity surgery often excludes a group of obese patients at risk of cardiovascular disease.

20 Dec 2007