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California halts medical parole, sends several critically ill patients back to prison

California has halted a court-ordered medical parole program, opting instead to send its most incapacitated prisoners back to state lockups or release them early.

21 Apr 2025

Differentiating cancerous and healthy cells through motion analysis

Researchers from Tokyo Metropolitan University have found that the motion of unlabeled cells can be used to tell whether they are cancerous or healthy.

20 Apr 2025

The lasting impact of paternal depression on children

In popular culture, dads are stoic, sensitive and strong. So powerful is the mystique of the happy dad that celebrities, joke books – even hard seltzers – carry the label.

20 Apr 2025

New therapeutic frontiers in the management of achondroplasia

A recent publication in Genes & Diseases has delivered a compelling synthesis of the latest insights into the cellular mechanisms and therapeutic interventions for achondroplasia, the most common form of genetic dwarfism.

20 Apr 2025

Molecular drivers and emerging treatments in anaplastic thyroid cancer

Anaplastic thyroid cancer (ATC), a rare yet highly aggressive malignancy, continues to represent a major clinical challenge.

20 Apr 2025

GOT2 as a metabolic and immunologic target in pancreatic cancer

A new wave of scientific interest is spotlighting GOT2—glutamic-oxaloacetic transaminase 2—as a compelling therapeutic target in the fight against pancreatic cancer, one of the most lethal and treatment-resistant malignancies.

20 Apr 2025

Reversing adipose tissue fibrosis through targeted microRNA therapies

A new review published in Genes & Diseases highlights the transformative role of microRNAs (miRNAs) in regulating and potentially reversing adipose tissue fibrosis, a condition closely linked to obesity, diabetes, and cardiovascular disease.

20 Apr 2025

Exploring citrullination as a key regulator of gene expression and disease

Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease.

20 Apr 2025

Lipid metabolism as a driver of therapy resistance in triple negative breast cancer

Lipid metabolism has emerged as a central player in the progression and therapy resistance of breast cancer, particularly the aggressive subtype known as triple-negative breast cancer (TNBC).

20 Apr 2025

Redefining cardiovascular medicine through the lens of sncRNAs

In a transformative review, small noncoding RNAs (sncRNAs) have emerged as pivotal regulators in the complex landscape of cardiovascular diseases.

20 Apr 2025

Unmasking Nrf2 as a key driver of treatment resistance in osteosarcoma

A deeper understanding of osteosarcoma, the most common primary malignant bone tumor affecting children and adolescents, is reshaping strategies for overcoming treatment resistance.

20 Apr 2025

Traditional BMI cut-offs overestimate overweight and obesity in male athletes

New research to be presented at this year's European Congress on Obesity (ECO 2025, Malaga, Spain, 11-14 May) shows that the internationally recognized body mass index (BMI) cut-off points greatly overestimate overweight and obesity in male athletes.

18 Apr 2025

Opioid control policies linked to drop in domestic violence

A new study led by the University of South Florida reveals opioid control policies may offer broader public health benefits, including reducing instances of domestic violence.

18 Apr 2025

Using AI to understand how the brain processes language during real-life conversations

We investigated how our brains process language during real-life conversations. Specifically, we wanted to understand which brain regions become active when we're speaking and listening, and how these patterns relate to the specific words and context of the conversation.

18 Apr 2025

The brain's visual system plays a bigger role in decision making than expected

When you see a bag of carrots at the grocery store, does your mind go to potatoes and parsnips or buffalo wings and celery?

18 Apr 2025

VR and AR simulations help people practice stress relief in realistic scenarios

Everyday situations can sometimes feel like big stressors, whether it's delivering an important work presentation, attending a party full of strangers or confronting a partner. Talking to a friend or a therapist can help. But so can practice.

18 Apr 2025

Insurance instability more common among low-income adults with diabetes

An Oregon Health & Science University-led study reveals that low-income adults with diabetes are more likely to go in and out of health insurance, and that insurance instability is even worse for those with complex needs.

18 Apr 2025

Scientists track liquid to solid shift in brain disease proteins

An international research collaboration led by Rutgers University-New Brunswick scientists that examined microscopic blobs of protein found in human cells has discovered that some morph from an almost honey-like substance to a hard candy-like solid.

18 Apr 2025

Targeting PGM3 offers new hope against deadly brain tumor

Researchers have found that targeting an enzyme called PGM3 can help stop the growth of glioblastoma, the most dangerous type of brain tumor.

18 Apr 2025

Monell study offers renewed hope for people living with Bardet-Biedl Syndrome

A Monell Chemical Senses Center study published this week in the Journal of Clinical Investigation offers renewed hope for individuals living with Bardet-Biedl Syndrome (BBS), a rare genetic disorder characterized by early-onset obesity, compulsive eating, and cognitive impairments.

18 Apr 2025