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Do hPSC-derived retinal neurons possess intrinsic potential to form new synaptic connections after extraction from organoids?

Researchers successfully demonstrated that lab-grown retinal organoids made new synaptic connections, theoretically establishing their potential to treat blindness due to retinal degenerative diseases.

13 Jan 2023

“Zone of uncertainty” communicates with the neocortex to rapidly control memory formation

The neocortex is the largest and most complex part of the brain and has long been considered the ultimate storage site for long-term memories. But how are traces of past events and experiences laid down there?

13 Jan 2023

Uncertainty increases when taking diagnostic tests “just to be on the safe side”

Paradoxical maybe, but it's what often happens in the health services: When you ask for an MRI to be on the safe side, your uncertainty increases, says Bjørn Hoffman, a professor at the Department of Health Sciences at the Norwegian University of Science and Technology, Gjøvik.

13 Jan 2023

Does COVID-19 pneumonia have a higher mortality rate than other causes of pneumonia?

A recent study evaluated outcomes in mechanically ventilated patients with pneumonia due to COVID-19 or other etiologies.

13 Jan 2023

Environmental and landscape changes linked to increase in hypertension risk

Researchers from China examined the impact of interactions between environmental factors such as heatwaves, air pollution, and the distribution of green and blue spaces on hypertension.

13 Jan 2023

Recent findings on original antigenic sin and SARS-CoV-2

Researchers collated the findings of studies relating original antigenic sin with SARS-CoV-2 evolution.

13 Jan 2023

Diabetes diagnosis is more positive in Norway, study says

Diabetes can have major consequences for the health and quality of life of affected people, especially when left undiagnosed. Fortunately, doctors are able to diagnose the vast majority of patients, who can then receive treatment.

13 Jan 2023

Review and meta-analysis suggests breathwork may be effective for improving stress and mental health

The findings of a study published in Scientific Reports suggest that practicing breathing exercises helps decrease stress and improve mental health.

13 Jan 2023

Protein discovery could lead to more effective treatments for lymphoma and lung cancer

Scientists from The Australian National University and the Peter MacCallum Cancer Centre have discovered that a protein, called Menin, contributes to abnormal deactivation of specific genes in cancer cells.

13 Jan 2023

Researchers study bacterial co-infections and antibiotic use in COVID-19 patients

Researchers estimated the frequency of bacterial co-infections among hospitalized coronavirus disease 2019 (COVID-19) patients and of antibiotic prescriptions in the initial COVID-19 period for appraising the usage of antibiotic stewardship criteria.

13 Jan 2023

What is pharmaceutical forecasting?

In this interview News Medical is talking to David James about pharmaceutical forecasting, J+D Forecasting solutions and their plans for the future.

From J+D Forecasting 13 Jan 2023

Study shows improved glucose control with fully closed-loop delivery of insulin in diabetics

Researchers investigated whether completely closed-loop insulin delivery could improve glycemic control among type 2 diabetes patients compared to regular insulin injections without any increase in hypoglycemia risks over 8.0 weeks of regular living.

13 Jan 2023

Ask voters directly, and abortion rights wins most ballot fights

This is shaping up as a critical year in the country's battle over abortion rights, as both sides struggle to define a new status quo after the Supreme Court struck down the nearly half-century-old constitutional right last year.

13 Jan 2023

Ending involuntary commitments would shift burden of dementia care to strapped communities

State lawmakers from both parties have shown support for a plan to stop the practice of committing people with Alzheimer's disease, other types of dementia, or traumatic brain injuries without their consent to the troubled Montana State Hospital and instead direct them to treatment in their communities.

13 Jan 2023

New cooling strategy could prevent the growth of glioblastoma

Cooling brain tumor cells to stop them from dividing without killing healthy cells extended the survival of glioblastoma (GBM) animal models dramatically in a study led by a UT Southwestern resident.

12 Jan 2023

Researchers to evaluate benefits of diet interventions in older adults with $2.1 million NIH grant

Maintaining a healthy weight during the golden years is a priority for many older adults. While previous research has shown that cutting calories can lower disease risk factors, it's unclear whether it can have a long-term positive impact on disease and disability.

12 Jan 2023

New breakthrough in understanding the genetic causes of "malformations of cortical development"

Epilepsy is present in 4% of the population, and is among the most common brain disorders in children. Modern medicine can prevent most seizure recurrences, but approximately 20% of patients do not respond to treatment.

12 Jan 2023

Discovery of a potential new target for new MPOX or broad pox vaccines

In a recent study posted to the medRxiv* preprint server, researchers in the United Kingdom developed a pooled enzyme-linked immunosorbent (ELISA) assay using mpox (MPX) virus (MPXV) antigens and vaccinia virus (VACV) antigens. They also assessed humoral responses to and identification of antigens of MPXV IIa clade and IIb clade, in comparison to recipients of smallpox vaccines (ACAM2000 and IMVANEX).

12 Jan 2023

Study on the ecology of viruses in urban rodents with special emphasis on SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, researchers investigated whether commensal rodent pests such as rats and mice, sourced from sewers and urban settings, are exposed to and are infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). They also investigated viruses present in commensal rodents.

12 Jan 2023

California Attorney General sues drugmakers over inflated insulin prices

California Attorney General Rob Bonta on Thursday sued the six major companies that dominate the U.S. insulin market, ratcheting up the state's assault on a profitable industry for artificially jacking up prices and making the indispensable drug less accessible for diabetes patients.

12 Jan 2023

Medical News

Do hPSC-derived retinal neurons possess intrinsic potential to form new synaptic connections after extraction from organoids?

“Zone of uncertainty” communicates with the neocortex to rapidly control memory formation

Uncertainty increases when taking diagnostic tests “just to be on the safe side”

Does COVID-19 pneumonia have a higher mortality rate than other causes of pneumonia?

Environmental and landscape changes linked to increase in hypertension risk

Recent findings on original antigenic sin and SARS-CoV-2

Diabetes diagnosis is more positive in Norway, study says

Review and meta-analysis suggests breathwork may be effective for improving stress and mental health

Protein discovery could lead to more effective treatments for lymphoma and lung cancer

Researchers study bacterial co-infections and antibiotic use in COVID-19 patients

What is pharmaceutical forecasting?

Study shows improved glucose control with fully closed-loop delivery of insulin in diabetics

Ask voters directly, and abortion rights wins most ballot fights

Ending involuntary commitments would shift burden of dementia care to strapped communities

New cooling strategy could prevent the growth of glioblastoma

Researchers to evaluate benefits of diet interventions in older adults with $2.1 million NIH grant

New breakthrough in understanding the genetic causes of "malformations of cortical development"

Discovery of a potential new target for new MPOX or broad pox vaccines

Study on the ecology of viruses in urban rodents with special emphasis on SARS-CoV-2

California Attorney General sues drugmakers over inflated insulin prices

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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