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Diverse subset of T-cell clones plays a role in the antitumor effects of immune checkpoint inhibitors

Immune checkpoint inhibitors (ICIs) are widely sought after for the treatment of different types of cancers. Unfortunately, only 20–30% patients with cancer respond to ICI treatment.

29 Mar 2023

Synthetic hydrogel-based lymphoma tumor model paves way for personalized cancer therapies

In recent years, innovative cancer drugs that target specific molecular drivers of the disease have been embraced as the treatment of choice for many types of cancer.

29 Mar 2023

Scientists uncover novel role of human-CIDEC gene in improving metabolic dysfunction and cardiovascular health

A team of researchers from Ohio University's Heritage College of Osteopathic Medicine recently discovered a novel role of human-CIDEC gene in improving metabolic dysfunction and cardiovascular health.

29 Mar 2023

Study investigates how loss of angulin-1/LSR affects the malignancy of lung adenocarcinoma

A new research paper was published in Oncotarget's Volume 14 on March 24, 2023, entitled, "Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-β-dependent cell metabolism in human lung adenocarcinoma A549 cells."

29 Mar 2023

Study shows benefits of expanding the use of telehealth services for people with opioid use disorder

The expanded availability of opioid use disorder-related telehealth services and medications during the COVID-19 pandemic was associated with a lowered likelihood of fatal drug overdose among Medicare beneficiaries, according to a new study.

29 Mar 2023

Johns Hopkins Medicine surgeons to receive $21.4 million to advance xenotransplantation research

As part of the worldwide effort to facilitate a research and clinical pathway toward successful xenotransplantation - the transplantation of living cells, tissues and organs from one species to another - two Johns Hopkins Medicine surgeons, Kazuhiko Yamada, M.D., Ph.D., and Andrew Cameron, M.D., Ph.D., will receive a total of $21.4 million in funding over the next two years under two sponsored research agreements with biotechnology company United Therapeutics Corporation.

29 Mar 2023

Cluster headache and migraine are strongly linked to the circadian system

Both cluster headache and migraine have strong links to the circadian system, the internal clock that regulates body processes, according to a meta-analysis published in the March 29, 2023, online issue of Neurology, the medical journal of the American Academy of Neurology.

29 Mar 2023

Study finds correlations between how and which organ systems are affected in individuals with new epileptic disorder

A recent study from Texas Children's Hospital and Baylor College of Medicine has expanded the clinical spectrum of a new epileptic disorder called Intellectual Developmental Disorder with Macrocephaly, Seizures, and Speech Delay (IDDMSSD) with the identification of the first recurrently affected residue identified in the protein kinase domain of PAK1 protein.

29 Mar 2023

Lab-made antibodies may be able to cure people infected with yellow fever

New research from Oregon Health & Science University and collaborators indicates lab-made antibodies may be able to cure people infected with yellow fever, a virus for which there is no treatment.

29 Mar 2023

Mouse avatars could help design more effective and personalized therapies for multiple myeloma

An international group of researchers, led by Dr. José Ángel Martínez-Climent at the Cima University of Navarra, has created mouse avatars of patients with multiple myeloma to study and develop personalized treatments against this blood cancer, the second most frequent hematological cancer and incurable in most cases.

29 Mar 2023

Experimental anti-obesity drug may control appetite without surgery or nausea

Imagine getting the benefits of gastric bypass surgery without going under the knife - a new class of compounds could do just that. In lab animals, these potential treatments reduce weight dramatically and lower blood glucose.

29 Mar 2023

Hemex Health awarded $3 million grant to advance commercialization of Gazelle Hb Variant Test for the U.S. market

Hemex Health, a medical diagnostic device company focused on expanding healthcare access to underrepresented patient populations, announced it has been awarded a 3-year, $3 million grant from the National Heart, Lung, and Blood Institute.

29 Mar 2023

Drugs to activate STING could help prevent cancer metastasis

A team of scientists at the Sloan Kettering Institute have identified the STING cellular signaling pathway as a key player in keeping dormant cancer cells from progressing into aggressive tumors months, or even years, after they've escaped from a primary tumor.

29 Mar 2023

Study offers a novel therapeutic option to combat antibiotic-resistant pneumonia

Increases in multidrug-resistance in the bacteria Streptococcus pneumoniae have made it the fourth-leading cause of death associated with antibiotic resistance.

29 Mar 2023

AI tool helps clinicians to identify and treat lung cancer at their early stages

A new artificial intelligence (AI) tool is helping physicians at Atrium Health Wake Forest Baptist better predict and diagnose lung cancer in patients.

29 Mar 2023

New method detects anxious and non-anxious depression using brain signal processing

A new method of detecting anxious and non-anxious depression using brain signal processing has been developed by biomedical engineers at the University of Surrey.

29 Mar 2023

Children exposed to pet cats or dogs during infancy may have fewer food allergies

In an analysis of over 65,000 infants from Japan, children exposed to pet cats or indoor dogs during fetal development or early infancy tended to have fewer food allergies compared to other children, according to a study published March 29, 2023 in the open-access journal PLOS ONE by Hisao Okabe from the Fukushima Regional Center for the Japan Environment and Children's Study, Japan, and colleagues.

29 Mar 2023

Medical News

Diverse subset of T-cell clones plays a role in the antitumor effects of immune checkpoint inhibitors

Synthetic hydrogel-based lymphoma tumor model paves way for personalized cancer therapies

Scientists uncover novel role of human-CIDEC gene in improving metabolic dysfunction and cardiovascular health

Study investigates how loss of angulin-1/LSR affects the malignancy of lung adenocarcinoma

Study shows benefits of expanding the use of telehealth services for people with opioid use disorder

Johns Hopkins Medicine surgeons to receive $21.4 million to advance xenotransplantation research

Cluster headache and migraine are strongly linked to the circadian system

Study finds correlations between how and which organ systems are affected in individuals with new epileptic disorder

Lab-made antibodies may be able to cure people infected with yellow fever

Mouse avatars could help design more effective and personalized therapies for multiple myeloma

Experimental anti-obesity drug may control appetite without surgery or nausea

Hemex Health awarded $3 million grant to advance commercialization of Gazelle Hb Variant Test for the U.S. market

Drugs to activate STING could help prevent cancer metastasis

Study offers a novel therapeutic option to combat antibiotic-resistant pneumonia

AI tool helps clinicians to identify and treat lung cancer at their early stages

New method detects anxious and non-anxious depression using brain signal processing

Children exposed to pet cats or dogs during infancy may have fewer food allergies

Study reveals dramatic rise in drug overdose fatalities among older adults in the past two decades

Advanced pancreatic cancer model more accurately depicts PDAC tumor progression

People with allergic diseases may be at heightened risk of osteoarthritis

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

Membrane proteins in focus: Turning high-risk targets into routine workflows

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