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Experts chart path to bring microbiome science into routine clinical care

Despite rapid advances in sequencing and bioinformatics, translating microbiome science into clinical practice presents significant challenges, including the lack of standardized protocols, limited clinical evidence, and logistical barriers. This Cell perspective outlines key actions, standardization, robust trial design, and clinician education to move microbiome diagnostics and therapeutics from bench to bedside.

2 Jun 2025

Airline pilots face high rates of anxiety and alcohol misuse, study finds

The mental health of airline pilots is at risk, with alarming rates of depression and alcohol misuse, necessitating urgent action for crew and passenger safety.

2 Jun 2025

Are parents adapting to new allergy prevention advice for infants?

The study finds parents often follow outdated practices for introducing first foods, underscoring the need for healthcare providers to share current guidelines.

1 Jun 2025

Digital baby formula campaigns undermine breastfeeding and put child health at risk

A global resolution on digital marketing of breast milk substitutes must be rigorously enforced, writes Afshan Khan, Assistant Secretary-General of the United Nations and coordinator of the Scaling Up Nutrition (SUN) Movement.

1 Jun 2025

Mouse study reveals harmful effects of polystyrene nanoplastics in food and beverages

Results from a new animal study suggest that microscopic plastic particles found in food and beverages may affect glucose metabolism and harm organs such as the liver.

1 Jun 2025

US funding freeze halts malaria prevention and genomic research

The “catastrophic” freeze on US funding for malaria has halted prevention programmes across Africa and also threatens to stall advances in genomic research, says Jane Carlton, director of the Johns Hopkins Malaria Research Institute.

1 Jun 2025

Healthy food choices found to be key in reducing heart disease risk

A new study that followed almost 200,000 people for several decades has found that when it comes to heart health, the quality of food consumed matters as much as following a low-carbohydrate or low-fat diet.

1 Jun 2025

Treatment switching guided by liquid biopsy results improves outcomes in advanced breast cancer

A large prospective, randomized clinical trial in patients with advanced breast cancer has found that the use of liquid biopsy blood tests for early detection of a treatment-resistance mutation, followed by a switch to a new type of treatment, substantially extends the period of tumor control compared to standard care.

1 Jun 2025

Linoleic acid may help to lower risks for heart disease and type 2 diabetes

New research that used blood markers to measure linoleic acid levels and their relation to cardiometabolic risk adds evidence that this omega-6 fatty acid may help to lower risks for heart disease and type 2 diabetes.

1 Jun 2025

Obesity associated with anxiety and cognitive impairment in mice

With rates of obesity and anxiety both on the rise-especially among younger Americans-new research suggests that the two conditions may be connected through interactions between the gut and the brain.

1 Jun 2025

Anti-inflammatory diet linked to longer survival in colon cancer patients

Patients with colon cancer who consumed an anti-inflammatory diet during a phase 3 clinical trial showed longer overall survival post-treatment compared to those on a proinflammatory diet, according to a Dana-Farber Cancer Institute analysis.

1 Jun 2025

Adding immunotherapy to chemotherapy after surgery improves survival in colon cancer

Colon cancer is the third most prevalent form of cancer in the U.S., and while screening has helped detect and prevent colon cancer from spreading, major advancements in treating colon cancer have lagged.

1 Jun 2025

Avelumab and cetuximab combination shows promise in phase II skin cancer trial

A phase II clinical trial led by the Alliance for Clinical Trials in Oncology has met its primary endpoint, demonstrating that the combination of avelumab and cetuximab improved progression-free survival (PFS) compared to avelumab alone in patients with advanced cutaneous squamous cell carcinoma (cSCC).

1 Jun 2025

Dual-target CAR T cell therapy shrinks tumors in aggressive brain cancer

A dual-target CAR T cell therapy approach shows promise for slowing tumor growth in a notoriously aggressive and fast-growing brain cancer.

1 Jun 2025

Tobacco-funded research continues to appear in leading medical journals

Tobacco-funded research is still appearing in highly-cited medical journals - despite attempts by some to cut ties altogether, finds an investigation by The Investigative Desk and The BMJ today.

1 Jun 2025

Scientists uncover how a single gene shaped the course of plague pandemic

Scientists have documented the way a single gene in the bacterium that causes bubonic plague, Yersinia pestis, allowed it to survive hundreds of years by adjusting its virulence and the length of time it took to kill its victims, but these forms of plague ultimately died out.

1 Jun 2025

Fathers' teenage diets linked to healthier eating habits in children

While moms have traditionally gotten much of the focus when it comes to children's eating habits, a new study highlights the importance of dads in shaping a child's relationship with food.

1 Jun 2025

Combination treatment extends progression-free survival in advanced skin cancer

In patients with an advanced type of skin cancer called cutaneous squamous cell carcinoma (cSCC), those who received the combination of the immunotherapy drug avelumab and targeted agent cetuximab had almost four times longer median progression-free survival compared to patients who received avelumab alone, according to the results of a phase 2 trial presented today at the American Society of Clinical Oncology (ASCO) meeting and concurrently published in the Journal of Clinical Oncology.

1 Jun 2025

Diagnostics.ai launches fully-transparent machine learning platform for real-time PCR diagnostics

As the May 26th CE-IVDR compliance deadline comes into effect, Diagnostics.ai launches the industry's first fully-transparent machine learning platform for clinical real-time PCR diagnostics – demonstrating exactly how each result was achieved, a first for molecular-testing machine learning.

31 May 2025

Gene expression study reveals clues to asbestos-linked mesothelioma

Gene expression leading to alterations in the DNA caused by asbestos exposure may explain the development of Malignant Pleural Mesothelioma (MPM), a rare and aggressive cancer.

31 May 2025