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C-Path and EJP RD collaborate to expand global rare disease research and drug development

Critical Path Institute (C-Path), an independent global nonprofit organization, and the European Joint Programme on Rare Diseases (EJP RD), an initiative that has received funding from the European Union's Horizon 2020 research and innovation programme, have announced a collaboration to advance technologies and methodologies that are fit for regulatory purposes to further global rare disease research and drug development.

1 Feb 2022

Neighborhood socioeconomic status associated with poorer patient outcomes after heart surgery

Patients with mitral valve disease who live in disadvantaged communities are more likely to experience complications and are at higher risk for death after surgery than those with higher socioeconomic status (SES), according to research presented at the 58th Annual Meeting of The Society of Thoracic Surgeons.

1 Feb 2022

New blood test quickly detects COVID-19 infection and disease severity

George Washington University researchers have developed a blood test that quickly detects if someone has COVID-19 and predicts how severely the immune system will react to the infection, according to a new study coming out today in PLOS One.

1 Feb 2022

Neural stem cells plus HER2 inhibitor drug improve survival in mice with metastatic cancer

Neural stem cells (NSCs) engineered by Northwestern Medicine investigators used in combination with the HER2 inhibitor drug tucatinib improved survival in mice with HER2-positive breast cancer brain metastases, according to findings published in Proceedings of the National Academy of Sciences.

1 Feb 2022

Scientists discover new insights about lymphangioleiomyomatosis

Researchers have discovered new insights about lymphangioleiomyomatosis (LAM), a rare lung disease, which affects about 1 in 200,00 Americans and commonly features the growth of abnormal cells in different tissues and organs, including the lungs.

1 Feb 2022

Zika virus vaccine candidate found to be safe and effective in preclinical animal studies

A Zika virus vaccine candidate is effective at preventing the Zika virus passing from mother to fetus in preclinical animal studies, according to a new study in the journal npj Vaccines.

1 Feb 2022

Mutational analysis of SARS-CoV-2 main protease

A new study discussed the findings of a comprehensive mutational analysis of the main protease (Mpro) of SARS-CoV-2.

1 Feb 2022

Assessing the effects of booster vaccinations against SARS-CoV-2 Omicron variant

In a new study, researchers analyzed the effect of vaccine booster doses against the SARS-CoV-2 Omicron variant.

1 Feb 2022

Daily physical activity boosts cognitive performance in middle-aged and older adults

A new study by researchers at University of California San Diego School of Medicine adds to the canon of research associating physical activity with cognitive performance, this time using 90 middle-aged and older subjects who wore accelerometers while physically active and completed mobile cognitive testing from home.

1 Feb 2022

£560 million funding will give young people access to more activities

Young people in England will be given access to more activities, trips away from home and volunteering opportunities as part of a new National Youth Guarantee backed by a £560 million investment, Culture Secretary Nadine Dorries announced today (1 February).

1 Feb 2022

Assessing the neutralizing ability of polyclonal antibody XAV-19 against SARS-CoV-2 Omicron variant

In a new study, a team of researchers assessed the neutralizing activity of XAV-19, a glyco-humanized polyclonal antibody derived from hyperimmunized animal hosts, against the SARS-CoV-2 Omicron variant.

1 Feb 2022

Impact of using AI to generate primers for detection of SARS-CoV-2 Omicron variant

In a new study, researchers designed artificial intelligence (AI)-based primers for the SARS-CoV-2 Omicron variant.

1 Feb 2022

SARS-CoV-2 protein NSP2 found to impair microRNA-induced gene silencing in human cells

In a new study, a team of researchers used co-immunoprecipitation and in vitro interaction assays to identify the molecular basis of interaction of SARS-CoV-2 non-structural protein 2 with eIF4E-homologous protein (4EHP)-GRB10-interacting glycine-tyrosine-phenylalanine domain protein 2 complex, involved in microRNA-mediated gene silencing in human cells.

1 Feb 2022

Illustrating the structural diversity of SARS-CoV-2 Omicron spike

In a new study, a team of researchers used cryo-electron microscopy to determine the spike (S) structures of the SARS-CoV-2 Omicron variant to understand how the mutations that alter its primary sequence impact S conformation.

1 Feb 2022

New WHO report highlights the scale and impact of COVID-19 waste problem

Tens of thousands of tonnes of extra medical waste from the response to the COVID-19 pandemic has put tremendous strain on health care waste management systems around the world, threatening human and environmental health and exposing a dire need to improve waste management practices, according to a new WHO report.

1 Feb 2022

Researchers explore natural SARS-CoV-2 infection in pet rabbits in France

In a new study, researchers reported the first evidence of natural SARS-CoV-2 infections among domestic rabbits in France.

1 Feb 2022

Exploring beta-coronavirus neutralization by vaccine-induced murine antibody WS6

In a new study, researchers evaluated the neutralizing antibody titers in mice vaccinated with messenger ribonucleic acid (mRNA) encoding SARS-CoV-2 spike (S) protein.

1 Feb 2022

Researchers conduct a living systematic review and meta-analysis on asymptomatic and pre-symptomatic SARS-CoV-2

In a new study, researchers aimed to understand and improve the changing COVID-19 evidence over time regarding three important review questions using a living systematic review.

1 Feb 2022

WHO urges everyone to confront inequalities that characterize neglected tropical diseases

To mark World Neglected Tropical Diseases Day (WNTDD), the World Health Organization is calling on everyone, to rally to confront inequalities that characterize NTDs and ensure that the poorest and marginalized communities who are mostly affected by neglected tropical diseases (NTDs) receive the health services they need.

1 Feb 2022

Faxes and snail mail: Will pandemic-era flaws unleash improved health technology?

Jamie Taylor received two letters from the Missouri Department of Social Services Family Support Division that began, "Good news," before stating that she was denied Medicaid coverage.

1 Feb 2022

Medical News

C-Path and EJP RD collaborate to expand global rare disease research and drug development

Neighborhood socioeconomic status associated with poorer patient outcomes after heart surgery

New blood test quickly detects COVID-19 infection and disease severity

Neural stem cells plus HER2 inhibitor drug improve survival in mice with metastatic cancer

Scientists discover new insights about lymphangioleiomyomatosis

Zika virus vaccine candidate found to be safe and effective in preclinical animal studies

Mutational analysis of SARS-CoV-2 main protease

Assessing the effects of booster vaccinations against SARS-CoV-2 Omicron variant

Daily physical activity boosts cognitive performance in middle-aged and older adults

£560 million funding will give young people access to more activities

Assessing the neutralizing ability of polyclonal antibody XAV-19 against SARS-CoV-2 Omicron variant

Impact of using AI to generate primers for detection of SARS-CoV-2 Omicron variant

SARS-CoV-2 protein NSP2 found to impair microRNA-induced gene silencing in human cells

Illustrating the structural diversity of SARS-CoV-2 Omicron spike

New WHO report highlights the scale and impact of COVID-19 waste problem

Researchers explore natural SARS-CoV-2 infection in pet rabbits in France

Exploring beta-coronavirus neutralization by vaccine-induced murine antibody WS6

Researchers conduct a living systematic review and meta-analysis on asymptomatic and pre-symptomatic SARS-CoV-2

WHO urges everyone to confront inequalities that characterize neglected tropical diseases

Faxes and snail mail: Will pandemic-era flaws unleash improved health technology?

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