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Human tissue xenografts in murine models for the study of SARS-CoV-2

Severe COVID-19 is associated with massive dysregulation of the host immune response, resulting in inflammation and the condition known as a cytokine storm. For the most part, however, the virus is barely noticeable or only mild among the young and healthy, suggesting that the route and intensity of an immune response could determine the severity of the disease.

20 Jul 2021

Scientists explore susceptibility of different animals to SARS-CoV-2 infection

A team of researchers at the Institute of Infectious Diseases (IFIK) at the University of Bern and the Institute of Virology and Immunology (IVI) has utilized a unique collection of advanced cell culture models of cells lining the airways from various domesticated and wildlife animals. This way, the team can determine which animals are susceptible to SARS-CoV-2 infection.

20 Jul 2021

Reusable N95 masks could offer reduction in waste and cost, study shows

Since the Covid-19 pandemic began last year, face masks and other personal protective equipment have become essential for health care workers. Disposable N95 masks have been in especially high demand to help prevent the spread of SARS-CoV-2, the virus that causes Covid-19.

20 Jul 2021

Potent nasal vaccine protects non-human primates from SARS-CoV-2

A team of US-based scientists has recently demonstrated the efficacy of a live attenuated, recombinant coronavirus disease 2019 (COVID-19) vaccine candidate currently under phase I clinical trial as a single-dose intranasal vaccine.

20 Jul 2021

UTHSC announces an increase in research grant and contract awards for FY21

The University of Tennessee Health Science Center's Office of Research announced that annual research grant and contract awards for FY21, which ended June 30, total more than $121 million, a 20.6% increase from last year.

20 Jul 2021

EWG study recommends stringent health-based standards for radiation exposure from wireless devices

A peer-reviewed study by the Environmental Working Group recommends stringent health-based exposure standards for both children and adults for radiofrequency radiation emitted from wireless devices. EWG's children's guideline is the first of its kind and fills a gap left by federal regulators.

20 Jul 2021

Study of COVID-19 shutdowns in the U.S. reveals pronounced disparities in air pollution

A new study of COVID-19 shutdowns in the United States reveals pronounced disparities in air pollution -- with disenfranchised, minority neighborhoods still experiencing more exposure to a harmful air pollutant compared to wealthier, white communities.

20 Jul 2021

Structural changes in receptor-binding interface may induce immune fitness of SARS-CoV-2 delta variant

Florida International University researchers have investigated the mutation-induced structural changes in the delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that could contribute to its immune evasion abilities.

20 Jul 2021

Frailty contributes to neurocognitive decline in young adult childhood cancer survivors

Scientists at St. Jude Children's Research Hospital have found a link between post-cancer treatment frailty and neurocognitive decline in young adult childhood cancer survivors. A paper on this work was published today in the Journal of Clinical Oncology.

20 Jul 2021

Maternal fecal transplant may help restore gut microbiota in newborns with diabetes risk

Newborns at risk for Type 1 diabetes because they were given antibiotics may have their gut microorganisms restored with a maternal fecal transplant, according to a Rutgers study.

20 Jul 2021

Study shows promise of combining radiation therapy with dendritic-cell vaccines for breast cancer

A research team led by Fumito Ito, MD, PhD, FACS, of Roswell Park Comprehensive Cancer Center reports new data on the promise of combining standard treatment for breast cancer with a particular form of cancer immmunotherapy - dendritic-cell (DC) treatment vaccines.

20 Jul 2021

MET amplification identified as a potentially actionable driver for non-small cell lung cancer

A study led by D. Ross Camidge, MD, PhD, director of thoracic oncology at the University of Colorado School of Medicine and CU Cancer Center member, has helped to define MET amplification as a rare but potentially actionable driver for non-small cell lung cancer (NSCLC).

20 Jul 2021

COVID-19 vaccination remains Australia's best option for a return to normal, say researchers

Researchers in Australia and the United States have advised that the recent decision in Australia to prioritize older vulnerable age groups for vaccination against coronavirus disease 2019 (COVID-19) represents the optimal strategy for reducing deaths caused by the disease.

20 Jul 2021

Research reveals clues to how a molecule improves appearance of surgery scars

Surgical scars treated with a molecule called alphaCT1 showed a long-term improvement in appearance when compared to control scars, according to multicenter, controlled Phase II clinical trials - a finding that could help surgeons improve patient outcomes.

20 Jul 2021

Improving access to mental health care among underserved populations

When it comes to improving access to mental health services for children and families in low-income communities, a University of Houston researcher found having a warm handoff, which is a transfer of care between a primary care physician and mental health provider, will help build trust with the patient and lead to successful outcomes.

20 Jul 2021

New study disproves suspicion that dengue raises risk of zika-related microcephaly

A pregnant woman infected by zika virus does not face a greater risk of giving birth to a baby with microcephaly if she has previously been exposed to dengue virus, according to a Brazilian study that compared data for pregnant women in Rio de Janeiro and Manaus.

20 Jul 2021

Targeting Piezo1 protein may be a new and ideal strategy to cure multiple sclerosis

In a new University of California, Irvine-led study, researchers found that a certain protein prevented regulatory T cells (Tregs) from effectively doing their job in controlling the damaging effects of inflammation in a model of multiple sclerosis (MS), a devastating autoimmune disease of the nervous system.

20 Jul 2021

Targeted mental health support lacking for people with chronic health conditions during pandemic

A new scoping review found that those with chronic health concerns, such as diabetes, heart disease, cancer, and autoimmune conditions, are not only at a higher risk of severe COVID-19 infection, they are also more likely to experience anxiety, depression or substance use during the COVID-19 pandemic.

20 Jul 2021

Next-generation COVID-19 vaccine provides robust immunity against SARS-CoV-2 in mice

Researchers in Canada have developed an adenoviral vector-based vaccine against coronavirus disease 2019 (COVID-19) that induced robust immune protection against the ancestral strain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in mice.

20 Jul 2021

IQWiG finds no benefit of high-flow therapy for COPD and type 1 respiratory failure

No benefit of high-flow therapy (HFT) can be derived from the available study data for patients with advanced chronic obstructive pulmonary disease (COPD) or chronic type 1 respiratory failure. It therefore remains unclear whether this form of treatment has advantages over long-term oxygen therapy (LTOT) or non-invasive ventilation (NIV).

20 Jul 2021

Medical News

Human tissue xenografts in murine models for the study of SARS-CoV-2

Scientists explore susceptibility of different animals to SARS-CoV-2 infection

Reusable N95 masks could offer reduction in waste and cost, study shows

Potent nasal vaccine protects non-human primates from SARS-CoV-2

UTHSC announces an increase in research grant and contract awards for FY21

EWG study recommends stringent health-based standards for radiation exposure from wireless devices

Study of COVID-19 shutdowns in the U.S. reveals pronounced disparities in air pollution

Structural changes in receptor-binding interface may induce immune fitness of SARS-CoV-2 delta variant

Frailty contributes to neurocognitive decline in young adult childhood cancer survivors

Maternal fecal transplant may help restore gut microbiota in newborns with diabetes risk

Study shows promise of combining radiation therapy with dendritic-cell vaccines for breast cancer

MET amplification identified as a potentially actionable driver for non-small cell lung cancer

COVID-19 vaccination remains Australia's best option for a return to normal, say researchers

Research reveals clues to how a molecule improves appearance of surgery scars

Improving access to mental health care among underserved populations

New study disproves suspicion that dengue raises risk of zika-related microcephaly

Targeting Piezo1 protein may be a new and ideal strategy to cure multiple sclerosis

Targeted mental health support lacking for people with chronic health conditions during pandemic

Next-generation COVID-19 vaccine provides robust immunity against SARS-CoV-2 in mice

IQWiG finds no benefit of high-flow therapy for COPD and type 1 respiratory failure

Voltammetry and machine learning for real-time neurotransmitter detection

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

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