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Iksuda Therapeutics closes $47 million financing round

Iksuda Therapeutics (Iksuda) has announced it has completed a US $47 million (circa GB £34 million) financing round, co-led by Mirae Asset Capital and its subsidiaries, Celltrion and Premier Partners, with the Company being advised by Ashfords LLP. The funding will support the advancement of Iksuda’s lead ADC assets and expansion of its payload and conjugation platform technologies.

From Iksuda Therapeutics 8 Jun 2021

Mass vaccination the only way to tackle emerging SARS-CoV-2 variants

Researchers from Poland recently analyzed key information concerning SARS-CoV-2 variants, such as their infectivity, mutations, severity, and immune susceptibility. Their work is published in the open-access journal Pathogens.

8 Jun 2021

Skin disorders on the rise during COVID‐19 pandemic due to infection and PPE use

An increase in personal protective equipment (PPE) use and hygiene measures such as the use of hand sanitizers, hand washing, and mask usage during this pandemic have increased the frequency of dermatological diseases.

8 Jun 2021

Combination of two early reading programs improves kindergarten readiness in preschool students

A study published in the journal Pediatrics shows the combination of two early reading programs had positive effects on preschool students entering kindergarten in Cincinnati Public Schools over a three-year period.

8 Jun 2021

Nanozymes to the rescue - potential role in fighting COVID-19

Over the last few decades, researchers have developed artificial enzymes for many applications. Recently, they deployed nanomaterial-based enzyme mimetics or nanozymes in diagnosis and therapeutics. Nanozymes find applications in various biomedical applications, including antiviral agents and cancer therapy.

8 Jun 2021

Immunomodulatory therapies for nephrological autoimmune diseases may help treat severe COVID-19

Various viruses and bacteria have long been known to cause autoimmune diseases where there is such a predisposition. This phenomenon also seems to play a major role in SARS-CoV-2, especially in severe courses.

8 Jun 2021

New study could help guide oncologists in selecting the best treatment for kidney cancers

Not all kidney cancers behave the same, with wildly different responses to immunotherapy or other treatments – and wildly different outcomes for patients as a result.

8 Jun 2021

No point vaccinating those who’ve had COVID-19: Cleveland Clinic study suggests

The study findings reveal that individuals with previous SARS-CoV-2 infection do not get additional benefits from vaccination, indicating that COVID-19 vaccines should be prioritized to individuals without prior infection. The study is currently available on the medRxiv* preprint server.

8 Jun 2021

Brain study may lead to new treatments for neuro-immune conditions

The immune system is the brain's best frenemy. It protects the brain from infection and helps injured tissues heal, but it also causes autoimmune diseases and creates inflammation that drives neurodegeneration.

8 Jun 2021

Study sheds new light on the mechanics and physics of blood clotting

Heart attacks and strokes - the leading causes of death in human beings - are fundamentally blood clots of the heart and brain. Better understanding how the blood-clotting process works and how to accelerate or slow down clotting, depending on the medical need, could save lives.

8 Jun 2021

Wearable sensor shows link between blood pressure and intracranial pressure

Brazilian researchers have simultaneously demonstrated the mechanism linking high blood pressure to elevated intracranial pressure, validated a non-invasive intracranial pressure monitoring method, and proposed a treatment for high blood pressure that does not affect intracranial hypertension.

8 Jun 2021

FDA approves monoclonal antibody aducanumab for treating Alzheimer's patients

Today's FDA approval of the monoclonal antibody Aduhelm (aducanumab) to treat patients with Alzheimer's disease reflects years of significant advances in Alzheimer's research. This is the first new Alzheimer's drug approved in 17 years and the first shown to modify the course of the disease, which FDA believes will lead to slowing of patients' cognitive decline.

8 Jun 2021

Drug sensitivity of hepatocellular cancer cells may provide new insights on tumor biology

Oncotarget published "Effect of cell microenvironment on the drug sensitivity of hepatocellular cancer cells" which reported that this study aimed to investigate whether Hepatocellular Cancer (HCC) cells cultured in more native conditions have an altered phenotype and drug sensitivity compared to those cultured in standard conditions.

8 Jun 2021

Lymphangiogenesis predicts favorable outcomes to immunotherapy

Oncotarget published "Mutually exclusive lymphangiogenesis or perineural infiltration in human skin squamous-cell carcinoma" which reported that although tumor-associated lymphangiogenesis correlates with metastasis and poor prognosis in several cancers, it also supports T cell infiltration into the tumor and predicts favorable outcome to immunotherapy.

8 Jun 2021

Study: COVID-19 produced more symptoms and complications than seasonal influenza in youths

A new global study of 30-day outcomes in children and adolescents with COVID-19 found that while death was uncommon, the illness produced more symptoms and complications than seasonal influenza.

8 Jun 2021

Chemical engineers devise a simpler process to incorporate hydrophobic drugs into tablets

About 60 percent of drugs on the market have hydrophobic molecules as their active ingredients. These drugs, which are not soluble in water, can be difficult to formulate into tablets because they need to be broken down into very small crystals in order to be absorbed by the human body.

8 Jun 2021

NIH researchers identify novel small molecule inhibitors of SARS-CoV-2 variants

A team of scientists from the National Institutes of Health (NIH), USA, has recently identified six novel small molecule inhibitors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its variants. The study is currently available on the bioRxiv* preprint server.

8 Jun 2021

New chip mimicking bovine endometrium could play key role in cattle’s pregnancy success

To investigate factors that can jeopardize pregnancy success in cattle, researchers at the University of São Paulo (USP) in Brazil used a kind of chip to mimic the environment of the endometrium, the tissue that lines the inside of the uterus.

8 Jun 2021

New technology can explain the effect of genetic factors on brain structure, function

Liang Zhan, assistant professor of electrical and computer engineering at Pitt's Swanson School of Engineering, received a $500,000 CAREER award from the National Science Foundation to develop computational tools that improve our understanding of the human brain.

8 Jun 2021

Bacteria causing urinary tract infections can originate in meat-production chain

In young women, Staphylococcus saprophyticus is a main cause of urinary tract infections (UTI), reaching 20% prevalence. Understanding the epidemiology of this microorganism can help identify its origin, distribution, causes, and risk factors.

8 Jun 2021

Medical News

Iksuda Therapeutics closes $47 million financing round

Mass vaccination the only way to tackle emerging SARS-CoV-2 variants

Skin disorders on the rise during COVID‐19 pandemic due to infection and PPE use

Combination of two early reading programs improves kindergarten readiness in preschool students

Nanozymes to the rescue - potential role in fighting COVID-19

Immunomodulatory therapies for nephrological autoimmune diseases may help treat severe COVID-19

New study could help guide oncologists in selecting the best treatment for kidney cancers

No point vaccinating those who’ve had COVID-19: Cleveland Clinic study suggests

Brain study may lead to new treatments for neuro-immune conditions

Study sheds new light on the mechanics and physics of blood clotting

Wearable sensor shows link between blood pressure and intracranial pressure

FDA approves monoclonal antibody aducanumab for treating Alzheimer's patients

Drug sensitivity of hepatocellular cancer cells may provide new insights on tumor biology

Lymphangiogenesis predicts favorable outcomes to immunotherapy

Study: COVID-19 produced more symptoms and complications than seasonal influenza in youths

Chemical engineers devise a simpler process to incorporate hydrophobic drugs into tablets

NIH researchers identify novel small molecule inhibitors of SARS-CoV-2 variants

New chip mimicking bovine endometrium could play key role in cattle’s pregnancy success

New technology can explain the effect of genetic factors on brain structure, function

Bacteria causing urinary tract infections can originate in meat-production chain

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

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