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Repeated low-dose dose exposure to SARS-CoV-2 may protect against severe COVID-19

The Italian authors of this paper, published in the journal Viruses, have taken this hypothesis and expanded it to include viral particles suspended in the air or on inanimate objects as a possible source of T cell immunity due to the repeated low-dose exposure, potentially explaining virus immunity found in non-infected individuals.

7 Jun 2021

Experimental monoclonal antibody could be a new weapon against HIV epidemic

An experimental, lab-made antibody can completely prevent nonhuman primates from being infected with the monkey form of HIV, new research published in Nature Communications shows.

7 Jun 2021

New model reveals the effectiveness of travel restrictions to slow COVID-19 transmission

More strategic and coordinated travel restrictions likely could have reduced the spread of COVID-19 in the early stages of the pandemic.

7 Jun 2021

Natural products show promise against COVID-19 via iron chelation

Researchers at the University of Catania in Italy investigated whether natural compounds could prevent disease progression. Their study published in the Journal of Clinical Medicine found that iron chelators and protease inhibitors can counteract SARS-CoV-2 infection.

7 Jun 2021

Redhill Biopharma announces completion of enrollment for oral opaganib phase 2/3 COVID-19 study

RedHill Biopharma Ltd., a specialty biopharmaceutical company, today announced that it has completed enrollment and randomized the last patient in the global Phase 2/3 study with opaganib (Yeliva, ABC294640) in patients hospitalized with severe COVID-19 pneumonia (NCT04467840).

7 Jun 2021

New edition of a best-selling handbook for sports coaches released

Ashley Gill, Course Director of Postgraduate Study in Sport and Exercise at Staffordshire University, has edited a fully revised third edition of the Routledge's popular Foundations of Sports Coaching textbook which was last published in 2014.

7 Jun 2021

International coalition develops classification criteria for 25 subtypes of uveitis

An international coalition of eye researchers used machine learning to develop classification criteria for 25 of the most common types of uveitis, a collection of over 30 diseases characterized by inflammation inside the eye.

7 Jun 2021

Discovery offers a potential new pathway to treat hypertension

High blood pressure, or hypertension, is the leading modifiable risk factor for cardiovascular diseases and premature death worldwide.

7 Jun 2021

Potential leptin therapy for nonalcoholic steatohepatitis

In those with fatty liver disease, a person's fat goes to their liver instead of their fat tissue, either because of an absence of fat depots, which is seen in the rare genetic disease lipodystrophy, or because the depots are too full, which is seen in people with obesity.

7 Jun 2021

The genetic diversity of SARS-CoV-2 in the USA

In a research paper recently uploaded to the preprint server medRxiv by Capoferri et al. (June 4th, 2021), the genetic diversity of SARS-CoV-2 through each phase is examined in detail using publicly available genomic data available from before 2021, highlighting the need to continuously track and assess the evolution of the virus to ensure the future efficacy of the currently available vaccines.

7 Jun 2021

Minimally-invasive procedure could offer hope to patients with high blood pressure

A minimally-invasive procedure that targets the nerves near the kidney has been found to significantly reduce blood pressure in hypertension patients, according to the results of a global multicentre clinical trial led in the UK by researchers at Queen Mary University of London and Barts Health NHS Trust.

7 Jun 2021

New report highlights enormous disease burden and treatment gap of osteoporosis in Europe

New International Osteoporosis Foundation report provides unique overview of osteoporosis in Europe, revealing the enormous disease burden and an unacceptable treatment gap; 71% of women at high risk of fracture are not receiving much-needed medication.

7 Jun 2021

Gene therapy may be a safe and effective single-dose treatment for soft bone disease

A preclinical study led by scientists at Sanford Burnham Prebys has established that AAV8-TNAP-D10--a gene therapy that replaces a key enzyme found in bone--may be a safe and effective single-dose treatment for hypophosphatasia (HPP).

7 Jun 2021

Genome-scale CRISPR screens pinpoint promising antiviral compounds against SARS-CoV-2

In a recent research paper currently available on the bioRxiv* preprint server, scientists in the US used genome-scale CRISPR knockout screens to identify factors that promote infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), revealing the potential for broad-spectrum activity across the coronavirus family.

7 Jun 2021

mRNA vaccines shown to be 97% protective against COVID-19 in working-age population

Researchers in the United States have demonstrated the effectiveness of messenger RNA (mRNA)-based vaccination at protecting against infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among almost 47,000 healthcare workers.

7 Jun 2021

Risk of SARS-CoV-2 transmission aboard aircraft is low: A review of evidence

Researchers in Romania, the UK, and Canada have systematically reviewed the evidence available on the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) aboard aircraft.

7 Jun 2021

FDA grants accelerated approval for first-of-its-kind Alzheimer's treatment

Today, the U.S. Food and Drug Administration approved Aduhelm (aducanumab) for the treatment of Alzheimer's, a debilitating disease affecting 6.2 million Americans. Aduhelm was approved using the accelerated approval pathway, which can be used for a drug for a serious or life-threatening illness that provides a meaningful therapeutic advantage over existing treatments.

7 Jun 2021

Medical News

Repeated low-dose dose exposure to SARS-CoV-2 may protect against severe COVID-19

Experimental monoclonal antibody could be a new weapon against HIV epidemic

New model reveals the effectiveness of travel restrictions to slow COVID-19 transmission

Natural products show promise against COVID-19 via iron chelation

Redhill Biopharma announces completion of enrollment for oral opaganib phase 2/3 COVID-19 study

New edition of a best-selling handbook for sports coaches released

International coalition develops classification criteria for 25 subtypes of uveitis

Discovery offers a potential new pathway to treat hypertension

Potential leptin therapy for nonalcoholic steatohepatitis

The genetic diversity of SARS-CoV-2 in the USA

Minimally-invasive procedure could offer hope to patients with high blood pressure

New report highlights enormous disease burden and treatment gap of osteoporosis in Europe

Gene therapy may be a safe and effective single-dose treatment for soft bone disease

Genome-scale CRISPR screens pinpoint promising antiviral compounds against SARS-CoV-2

mRNA vaccines shown to be 97% protective against COVID-19 in working-age population

Risk of SARS-CoV-2 transmission aboard aircraft is low: A review of evidence

FDA grants accelerated approval for first-of-its-kind Alzheimer's treatment

Study finds high levels of lead in indigenous people in Peruvian Amazonia

Study identifies new drug to halt dementia in athletes after repeated head injuries

Study observes broad and invariable memory B cell response following SARS-CoV-2 infection

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

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