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SARS-CoV-2 spike stimulates hyperinflammation via Toll-like receptor 2

A new study, released on the bioRxiv* preprint server, describes the mechanism of inflammation in severe COVID-19, besides revealing a potential new therapeutic target to modulate the severity of COVID-19.

19 Mar 2021

DNA spike-ins increase reliability of amplicon-based sequencing of SARS-CoV-2 genomes

In the interests of cost-effectiveness and rapidity, amplicon-based sequencing of the viral genome has been used to provide a sensitive means of genomic surveillance. A new preprint, which was released on the bioRxiv* server, shows how this can be tweaked to make it a reliable source of genomic data by reducing the known potential for contamination.

19 Mar 2021

Covid-inspired Montana health insurance proposal wouldn’t kick in for 2 years

For employees of small businesses in Montana suddenly laid off during the covid-19 pandemic, maintaining health insurance coverage could be a struggle.

19 Mar 2021

Doctors found jet fuel in veteran’s lungs. He can’t get full benefits.

The lungs Bill Thompson was born with told a gruesome, harrowing and unmistakable tale to Dr. Anthony Szema when he analyzed them and found the black spots, scarring, partially combusted jet fuel and metal inside.

19 Mar 2021

The case for donating US Covid vaccines overseas

A Senate committee grilled federal officials about the shortage of vaccines to protect Americans against a pandemic virus. Two months later, the U.S. public had lost interest in the virus, and millions of vaccines were sitting in warehouses — although poor countries still needed them.

19 Mar 2021

New variant may not have changed COVID-19 pandemic course in UK, says study

A new study examines the effect of the new "Kent variant" of SARS-CoV-2 on the epidemic course within the UK.

19 Mar 2021

Researchers explore nanotechnology’s potential to deliver synergistic therapeutics for COVID-19

A team of scientists reviewed the nanoencapsulation approaches of synergistic compounds (Lectins, Caffeine, Cocoa, Flavonoids, Quercetin) and the role of nanotechnology in addressing the COVID-19 pandemic.

19 Mar 2021

Study examines efficacy of Pfizer-BioNTech mRNA COVID-19 vaccine across demographic groups

A new study examines data from Israel's vaccination campaign to assess the efficacy of the Pfizer-BioNTech mRNA vaccine across different demographics.

19 Mar 2021

Maintaining a stable body weight does not reduce risk of death in colorectal cancer survivors

Colorectal cancer survivors who maintained a stable body weight but lost muscle and developed fatty deposits in their muscles faced a 40 percent higher risk of premature death than patients who avoided both health issues.

19 Mar 2021

Diagnostic test helps identify the virulent forms of swine bacterial pathogens

A team led by researchers in Penn State's College of Agricultural Sciences has developed a diagnostic test that can identify virulent forms of the swine bacterial pathogen Streptococcus equi subspecies zooepidemicus -- often referred to as "Strep zoo" -- which can cause severe illness and death in pigs, other animals and rarely people.

19 Mar 2021

Researchers investigate the effect of COVID-19 vaccines on residents of long-term care homes

Long-term care homes have been at the epicenter of the COVID-19 pandemic in Canada, with 70 percent of COVID-19 deaths having occurred in long-term care or nursing homes.

19 Mar 2021

New proteomics method helps confirm COVID-19 transmission from mother to fetus

Researchers from Skoltech were part of a research consortium studying a case of vertical COVID-19 transmission from mother to her unborn child that resulted in major complications in the pregnancy, premature birth and death of the child.

19 Mar 2021

New autonomous technology helps track the daily patterns of isolated older relatives

Researchers are developing new autonomous technologies that can help people check that isolated elderly family members are okay.

19 Mar 2021

Study reveals how SARS-CoV-2 spread in Wuhan before the lockdown

Using molecular dating tools and epidemiological simulations, researchers at University of California San Diego School of Medicine, with colleagues at the University of Arizona and Illumina, Inc., estimate that the SARS-CoV-2 virus was likely circulating undetected for at most two months before the first human cases of COVID-19 were described in Wuhan, China in late-December 2019.

19 Mar 2021

New drug regimen is safe and effective in children with cystic fibrosis

An international, open-label Phase 3 study, co-led by Susanna McColley, MD, from Ann & Robert H. Lurie Children's Hospital of Chicago, found that a regimen of three drugs (elexacaftor/tezacaftor/ivacaftor) that targets the genetic cause of cystic fibrosis was safe and effective in 6-11-year-olds with at least one copy of F508del mutation in the CFTR gene, which is estimated to represent almost 90 percent of the cystic fibrosis population in the United States.

19 Mar 2021

Study: Mobile stroke units reduce disability, improve outcomes in stroke patients

Stroke patients treated via a mobile stroke unit (MSU) received clot-busting medications faster and more often - and recovered significantly better than patients who receive regular emergency care by standard ambulance.

19 Mar 2021

Researchers find stark disparities in COVID-19 outcomes

Researchers at Seattle's Institute for Systems Biology and their collaborators looked at the electronic health records of nearly 630,000 patients who were tested for SARS-CoV-2, and found stark disparities in COVID-19 outcomes -- odds of infection, hospitalization, and in-hospital mortality -- between White and non-White minority racial and ethnic groups.

19 Mar 2021

Scientists use clinical data to study the molecular groups of atypical teratoid rhabdoid tumor

Atypical teratoid rhabdoid tumor (ATRT) is a rare brain tumor that predominantly occurs in young children. Scientists at St. Jude Children's Research Hospital used data from two clinical trials to study the molecular groups of ATRT and correlate them with clinical outcomes.

19 Mar 2021

Alliance for Cancer Gene Therapy provides new opportunity to develop cancer cell and gene therapies

Alliance for Cancer Gene Therapy wants to change the C-word from Cancer to Cure -- building on the life changing success of CAR-T therapies for blood cancers, the organization is now focused on the urgent need to translate this success into therapies to fight more types of cancer, such as solid tumor cancers.

19 Mar 2021

Rare pulmonary disease discovered in rural Alberta

A rare pulmonary disease that is linked to bats has made Alberta home, according to new research led by provincial lab scientists.

19 Mar 2021

Medical News

SARS-CoV-2 spike stimulates hyperinflammation via Toll-like receptor 2

DNA spike-ins increase reliability of amplicon-based sequencing of SARS-CoV-2 genomes

Covid-inspired Montana health insurance proposal wouldn’t kick in for 2 years

Doctors found jet fuel in veteran’s lungs. He can’t get full benefits.

The case for donating US Covid vaccines overseas

New variant may not have changed COVID-19 pandemic course in UK, says study

Researchers explore nanotechnology’s potential to deliver synergistic therapeutics for COVID-19

Study examines efficacy of Pfizer-BioNTech mRNA COVID-19 vaccine across demographic groups

Maintaining a stable body weight does not reduce risk of death in colorectal cancer survivors

Diagnostic test helps identify the virulent forms of swine bacterial pathogens

Researchers investigate the effect of COVID-19 vaccines on residents of long-term care homes

New proteomics method helps confirm COVID-19 transmission from mother to fetus

New autonomous technology helps track the daily patterns of isolated older relatives

Study reveals how SARS-CoV-2 spread in Wuhan before the lockdown

New drug regimen is safe and effective in children with cystic fibrosis

Study: Mobile stroke units reduce disability, improve outcomes in stroke patients

Researchers find stark disparities in COVID-19 outcomes

Scientists use clinical data to study the molecular groups of atypical teratoid rhabdoid tumor

Alliance for Cancer Gene Therapy provides new opportunity to develop cancer cell and gene therapies

Rare pulmonary disease discovered in rural Alberta

Voltammetry and machine learning for real-time neurotransmitter detection

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

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