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Exposure to COVID-19 can cause rare but life-threatening pediatric condition

Exposure to SARS-Co-V2, the virus that causes COVID-19, can put otherwise healthy children and adolescents at risk for Multisystem Inflammatory Syndrome in Children (MIS-C), a rare but possibly life-threatening pediatric condition that can cause severe inflammation in organs like the heart, brain, lungs, kidneys and gastrointestinal system.

12 Mar 2021

New approach could treat infertility caused by abnormal GnRH secretion

Reports suggest that at least 25% of ovarian disorders are due to dysfunction of the brain mechanism in the hypothalamus that controls the gonadotropin-releasing hormone (GnRH), which is a molecule that governs the reproductive function in men and women by regulating the release of a range of reproductive hormones into the body, particularly gonadotropins, from the pituitary gland, which is located underneath the brain.

12 Mar 2021

A new methodology to define and diagnose problematic video gaming

In 2019, the World Health Organization recognised Gaming disorder as a clinical condition, but the proposed diagnostic criteria and clinical guidelines remain the subject of an intense scientific debate.

12 Mar 2021

Spike protein mutations in SARS-CoV-2 variants help resist antibody neutralization

Researchers based in Beijing and Shenzhen, China, report that they have identified mutations in the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that may allow variant strains to avoid neutralization by monoclonal antibodies and convalescent blood plasma.

11 Mar 2021

N501Y mutation in SARS-CoV-2 responsible for increased viral transmission

Researchers at the University of Texas, USA, have confirmed the specific mutation in the B.1.1.7 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), has allowed for it to be more transmissible than the ancestral strain. The N501Y substitution is one of 8 spike protein substitutions present in the UK variant and has also appeared convergently in the Brazil (P.1) and South Africa (B.1.351) variants.

11 Mar 2021

Structure and function of locked conformation of the SARS-CoV-2 spike protein identified

A new preprint research paper, posted to the bioRxiv* server, uncovered more information on the different structural conformations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The findings suggest the spike protein turns into a locked state to stabilize the spike protein during virus egress.

11 Mar 2021

Delaying second dose of Pfizer-BioNTech SARS-CoV-2 vaccine may be feasible in some cases

Researchers in Spain have conducted the most extensive study to date investigating the effectiveness of vaccinating healthcare workers with a single dose of the Pfizer-BioNTech vaccine to protect against coronavirus disease 2019 (COVID-19).

11 Mar 2021

Study addresses glycosylation concerns in SARS-CoV-2 vaccine design

An international team of researchers has found that glycosylation patterns are conserved across the native spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – and the recombinant spike proteins made in laboratories for use in vaccines.

11 Mar 2021

Americans coping with pandemic stress report undesired changes to weight, increased drinking

As growing vaccine demand signals a potential turning point in the global COVID-19 pandemic, the nation's health crisis is far from over.

11 Mar 2021

Early tracheotomy shortens ICU stay and lowers risk of ventilator-associated pneumonia

Surgically opening the windpipe, or trachea, within the first seven days of the start of mechanical ventilation decreases the time patients spend on ventilators, shortens their ICU stay and lowers their risk of ventilator-associated pneumonia, according to a systematic review published Thursday (March 11) in JAMA Otolaryngology-Head & Neck Surgery.

11 Mar 2021

NCCN publishes new guidance for management of COVID-19 in cancer patients

The National Comprehensive Cancer Network--an alliance of leading cancer centers--has published new best practice recommendations for Management of COVID-19 Infection in Patients with Cancer.

11 Mar 2021

Henry Ford Cancer Institute launches new initiative to improve minority participation in clinical trials

Henry Ford Cancer Institute is launching the Participatory Action for Access to Clinical Trials (PAACT) project to dramatically improve the representation of the African American community and other minorities in cancer clinical trials.

11 Mar 2021

Jobs with greater risk for COVID-19 exposure have high number of Black or Hispanic workers

Black and Hispanic people experience a higher risk for COVID-19 and severe illness, influenced by factors such as discrimination, housing, and healthcare access and utilization.

11 Mar 2021

Researchers discover new protein that may play a key role in atherosclerosis

Atherosclerosis is the underlying condition that causes heart attacks and strokes. Researchers at Radboudumc in the Netherlands have discovered a protein that appears to play an important role in atherosclerosis.

11 Mar 2021

Studies reveal how kidney tumors' microenvironments change in response to immunotherapy

In the last two decades, immunotherapy has emerged as a leading treatment for advanced renal carcinoma cancer (more commonly known as kidney cancer).

11 Mar 2021

One in four people could face some degree of hearing loss by 2050, WHO report warns

One in four people across the world — nearly 2.5 billion — could face some degree of hearing loss by 2050 with at least 700 million requiring access to treatment and rehabilitation, a WHO report warns.

11 Mar 2021

VEXAS syndrome in men is more common than previously thought

A rare disease first identified in 2020 is much more common than first thought, say researchers at the University of Leeds investigating its origins.

11 Mar 2021

Delays in treatment at the hospital may have severe consequences on stroke recovery

For every 10-minute delay between arrival at the emergency room (ER) and starting stroke treatment, patients with severe strokes may lose eight weeks of healthy life, according to preliminary research to be presented at the American Stroke Association's International Stroke Conference 2021.

11 Mar 2021

Women with non-O type blood who smoke, take oral contraceptives more likely to have a stroke

Non-O blood type may increase the risk of stroke among women who smoke and take oral contraceptives, according to preliminary research to be presented at the American Stroke Association's International Stroke Conference 2021.

11 Mar 2021

NIAID awards $2.5 million in grants to support research on bacteriophage therapy

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has awarded $2.5 million in grants to 12 institutes around the world to support research on bacteriophage therapy.

11 Mar 2021

Medical News

Exposure to COVID-19 can cause rare but life-threatening pediatric condition

New approach could treat infertility caused by abnormal GnRH secretion

A new methodology to define and diagnose problematic video gaming

Spike protein mutations in SARS-CoV-2 variants help resist antibody neutralization

N501Y mutation in SARS-CoV-2 responsible for increased viral transmission

Structure and function of locked conformation of the SARS-CoV-2 spike protein identified

Delaying second dose of Pfizer-BioNTech SARS-CoV-2 vaccine may be feasible in some cases

Study addresses glycosylation concerns in SARS-CoV-2 vaccine design

Americans coping with pandemic stress report undesired changes to weight, increased drinking

Early tracheotomy shortens ICU stay and lowers risk of ventilator-associated pneumonia

NCCN publishes new guidance for management of COVID-19 in cancer patients

Henry Ford Cancer Institute launches new initiative to improve minority participation in clinical trials

Jobs with greater risk for COVID-19 exposure have high number of Black or Hispanic workers

Researchers discover new protein that may play a key role in atherosclerosis

Studies reveal how kidney tumors' microenvironments change in response to immunotherapy

One in four people could face some degree of hearing loss by 2050, WHO report warns

VEXAS syndrome in men is more common than previously thought

Delays in treatment at the hospital may have severe consequences on stroke recovery

Women with non-O type blood who smoke, take oral contraceptives more likely to have a stroke

NIAID awards $2.5 million in grants to support research on bacteriophage therapy

Voltammetry and machine learning for real-time neurotransmitter detection

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

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