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Pancreatic β cells secrete miR-29 in response to high levels of free fatty acids

In a new study published in Journal of Extracellular Vesicles, Chen-Yu Zhang's group and Antonio Vidal-Puig's group at University of Cambridge report that pancreatic β cells secrete miR-29 family members (miR-29a, miR-29b and miR-29c) in response to high levels of free fatty acids (FFAs). These β cell-derived miR-29s are delivered to the liver, promoting insulin resistance and enhancing hepatic glucose output.

9 Feb 2021

Delayed reactions and decentralized approach on 1918 pandemic had more fatal consequences

In the event of a pandemic, delayed reactions and a decentralized approach by the authorities at the start of a follow-up wave can lead to longer-lasting, more severe and more fatal consequences, researchers from the universities of Zurich and Toronto have found.

9 Feb 2021

New machine-learning algorithm estimates number of COVID-19 cases in the U.S.

World health experts have long suspected that the incidence of COVID-19 has been higher than reported. Now, a machine-learning algorithm developed at UT Southwestern estimates that the number of COVID-19 cases in the U.S. since the pandemic began is nearly three times that of confirmed cases.

8 Feb 2021

Human-caused climate change plays key role in allergy outcomes

If you live with seasonal allergies and feel like the pollen seasons feel longer and longer every year, you may be right. New research shows that pollen seasons start 20 days earlier, are 10 days longer, and feature 21% more pollen than in 1990 - meaning more days of itchy, sneezy, drippy misery.

8 Feb 2021

Researchers look at long-term outcomes of cancer patients diagnosed with COVID-19

Researchers at MUSC Hollings Cancer Center have joined a nationwide study to look at the long-term outcomes of cancer patients who have been diagnosed with COVID-19.

8 Feb 2021

Wearable devices can identify COVID-19 cases earlier than traditional diagnostic methods

Wearable devices can identify COVID-19 cases earlier than traditional diagnostic methods and can help track and improve management of the disease, Mount Sinai researchers report in one of the first studies on the topic. The findings were published in the Journal of Medical Internet Research on January 29.

8 Feb 2021

Differences in gene readouts may shed light on mental disorders

A new study suggests that differences in the expression of gene transcripts - readouts copied from DNA that help maintain and build our cells - may hold the key to understanding how mental disorders with shared genetic risk factors result in different patterns of onset, symptoms, course of illness, and treatment responses

8 Feb 2021

New U.K. SARS-CoV-2 variant may cause more severe illness, study finds

Researchers at the London School of Hygiene and Tropical Medicine revealed that the VOC 202012/01 variant is not only fast-spreading and easily transmissible but also may cause more severe illness.

8 Feb 2021

New study identifies best practices to improve breastfeeding in African American community

An abundance of data underscore the importance of breastfeeding and human milk for the optimal health of infants, children, mothers, and society.

8 Feb 2021

Type of aspirating system significantly affects SARS-CoV-2 incidence among dental specialists

High-volume aspirators are recommended in dental clinics during the COVID-19 pandemic, but the study "SARS-CoV-2 Seropositivity Among Dental Staff and the Role of Aspirating Systems" published in the JDR Clinical & Translational Research (JDR CTR), shows that the type of aspirating system significantly affects the incidence of SARS-CoV-2 infection among dental specialists.

8 Feb 2021

New platform could help advance genomic medicine research, drug discovery

A Cleveland Clinic-led team of researchers has developed a personalized genomic medicine platform that will help advance accelerate genomic medicine research and genome-informed drug discovery, according to new study results published recently in Genome Biology.

8 Feb 2021

One-dose SARS-CoV-2 vaccine policy may lead to antigenic evolution, study finds

In a new study, published on the pre-print server medRxiv, an international team of researchers found that a one-dose policy may increase the potential for antigenic evolution. The study revealed that focusing on one dose may decrease infections in the short term, but longer-term outcomes rely on this immune strength.

8 Feb 2021

HIV: New therapeutic approach to restore the effectiveness of immune cells

Prompted by the need to improve conventional treatments for people infected with the human immunodeficiency virus (HIV-1), a team from the Institut national de la recherche scientifique has identified a therapeutic approach to restore the effectiveness of immune cells.

8 Feb 2021

Compound isolated from Ophiura sarsii can be used as an affordable drug for photodynamic therapy

An unusual biologically active porphyrin compound was isolated from seabed dweller Ophiura sarsii. The substance might be used as an affordable light-sensitive drug for innovative photodynamic therapy and for targeted treatment of triple-negative breast cancer and some other cancers.

8 Feb 2021

Study: Older adults classified as "prediabetic" seldom progress to full diabetes

Older adults who are classified as having "prediabetes" due to moderately elevated measures of blood sugar usually don't go on to develop full-blown diabetes, according to a study led by researchers at Johns Hopkins Bloomberg School of Public Health.

8 Feb 2021

Pfizer-BioNTech COVID-19 vaccine immune response in the elderly

In a recent medRxiv preprint publication, the team led by Professor Ravindra K. Gupta has assessed the real-world immune responses following the vaccination against the SARS-CoV-2. The team measured 1) IFN-gamma (interferon-gamma) T cell responses, 2) both total IgG Spike/ IgG Spike RBD (receptor binding domain) and 3) neutralizing antibody responses to Spike in sera.

8 Feb 2021

New study to examine the effects of MS disease-modifying therapy on cognitive fatigue

Kessler Foundation researchers have received support from Genentech, a member of the Roche Group, to conduct an investigator-initiated study on the effects of ocrelizumab (Ocrevus) on cognitive fatigue in individuals with relapsing-remitting multiple sclerosis (MS).

8 Feb 2021

Take-at-home tests increase colorectal cancer screening rates by more than 1,000%

Colorectal cancer screening rates jumped by more than 1,000 percent when researchers sent take-at-home tests to patients overdue for testing at a community health center that predominantly serves people of color.

8 Feb 2021

Analysis finds racial and ethnic disparities in the odds of testing positive for COVID-19

An analysis of Kaiser Permanente members in Northern California early in the COVID-19 pandemic found racial and ethnic disparities in the likelihood of testing positive for the coronavirus, but no significant disparities in mortality among those who were hospitalized.

8 Feb 2021

Study examines people's behavioral responses to face mask mandates during the pandemic

Face masks mandates have led people to spend less time at home, but whether this has exposed Americans to more risk is still a question, according to a new study published Thursday in Scientific Reports.

8 Feb 2021

Medical News

Pancreatic β cells secrete miR-29 in response to high levels of free fatty acids

Delayed reactions and decentralized approach on 1918 pandemic had more fatal consequences

New machine-learning algorithm estimates number of COVID-19 cases in the U.S.

Human-caused climate change plays key role in allergy outcomes

Researchers look at long-term outcomes of cancer patients diagnosed with COVID-19

Wearable devices can identify COVID-19 cases earlier than traditional diagnostic methods

Differences in gene readouts may shed light on mental disorders

New U.K. SARS-CoV-2 variant may cause more severe illness, study finds

New study identifies best practices to improve breastfeeding in African American community

Type of aspirating system significantly affects SARS-CoV-2 incidence among dental specialists

New platform could help advance genomic medicine research, drug discovery

One-dose SARS-CoV-2 vaccine policy may lead to antigenic evolution, study finds

HIV: New therapeutic approach to restore the effectiveness of immune cells

Compound isolated from Ophiura sarsii can be used as an affordable drug for photodynamic therapy

Study: Older adults classified as "prediabetic" seldom progress to full diabetes

Pfizer-BioNTech COVID-19 vaccine immune response in the elderly

New study to examine the effects of MS disease-modifying therapy on cognitive fatigue

Take-at-home tests increase colorectal cancer screening rates by more than 1,000%

Analysis finds racial and ethnic disparities in the odds of testing positive for COVID-19

Study examines people's behavioral responses to face mask mandates during the pandemic

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

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