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Tumor microbiota identified as predictors of prognosis in gastrointestinal cancers

Microbes inside cancerous tumors can influence the spread of disease and the effectiveness of treatment. Those roles make them appealing targets for new therapies and offer ways to better predict risk.

28 Aug 2025

How can medical trainees use AI without losing critical thinking skills?

A NEJM review outlines how large language models (LLMs) are reshaping medical education, posing risks of deskilling, never-skilling, and mis-skilling among trainees.

28 Aug 2025

First clinical trial in cats tests targeted therapy for deadly head and neck cancer

Researchers have reported results from the first-ever clinical trial of a new class of targeted therapy in pet cats with head and neck squamous cell carcinoma (HNSCC)-a cancer which is notoriously deadly and difficult to treat.

28 Aug 2025

UC San Diego Health performs world’s first personalized spine surgery

UC San Diego Health is the first health system in the world to perform an anterior cervical spine surgery using a fully personalized implant designed for a patient's unique anatomy.

28 Aug 2025

Ultra-processed foods harm reproductive and metabolic health

Over the past 50 years, rates of obesity and type-2 diabetes have soared, while sperm quality has plummeted. Driving these changes could be the increasing popularity of ultra-processed foods, which have been linked to a range of poor health outcomes.

28 Aug 2025

Cardiovascular outcomes worsen in patients with mental health conditions

Every 34 seconds, someone in the United States dies from heart disease. As nearly half of the country suffers from some form of cardiovascular disease (CVD), another 1 in 4 adults experience a mental health disorder in their lifetime, signaling an inevitable overlap.

28 Aug 2025

Older adults reveal what makes or breaks a shift to plant-based protein

Older Dutch adults identified health and taste as the key tipping points for shifting toward protein-rich plant-based diets. Knowledge, social context, and practical tools shaped adoption, while skepticism and habits limited change.

28 Aug 2025

Gut disorders forecast Alzheimer’s and Parkinson’s risk years before diagnosis

Study maps clinical, genetic, and proteomic links between gut-brain disorders and neurodegeneration, showing how diabetes, vitamin D deficiency, and bowel disorders forecast Alzheimer’s and Parkinson’s years in advance. Multimodal models in biobanks highlight early detection and personalized prevention opportunities.

28 Aug 2025

Evidence-based calculator to guide hypertension treatment choices

A first-of-its-kind Blood Pressure Treatment Efficacy Calculator built on data from nearly 500 randomized clinical trials in over 100,000 people allows doctors to see by how much different medications are likely to lower blood pressure.

28 Aug 2025

Research sheds new light on depression’s biological roots

Researchers at McGill University and the Douglas Institute have identified two specific types of brain cells that are altered in people with depression.

28 Aug 2025

Most Americans unaware that early prostate cancer shows no symptoms

A recent survey commissioned by The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) focused on Americans' awareness of the signs and symptoms of prostate cancer.

28 Aug 2025

Study brings hope for a more personalized approach to treat ER+ breast cancer

A new study from researchers at Baylor College of Medicine brings hope for a more personalized approach to treat estrogen receptor-positive (ER+) breast cancer, the most common type of this cancer.

28 Aug 2025

Placebo study uncovers a precise pain map in the human brainstem

Researchers from the University of Sydney have used placebo pain relief to uncover a map-like system in the brainstem that controls pain differently depending on where it's felt in the body.

28 Aug 2025

AI and routine lab tests offer a more accurate prediction of genetic disease risk

When genetic testing reveals a rare DNA mutation, doctors and patients are frequently left in the dark about what it actually means.

28 Aug 2025

Molecular profiling identifies prostate cancer patients who benefit most from chemotherapy

Testing the molecular profile of tumors identifies which patients with advanced prostate cancer are more likely to benefit from chemotherapy and live longer, sparing patients less likely to benefit from unpleasant side effects, according to a new study led by UCL researchers.

28 Aug 2025