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Researchers develop bioprinted skin model of cutaneous squamous cell carcinoma

The cover for issue 27 of Oncotarget features "Bimodal imaging examples of control and treated tumors (red) before and after the treatment period," by Browning, et al. and reported that the authors developed a 3-dimensional bioprinted skin model of cutaneous squamous cell carcinoma (cSCC) tumors together with a microscopy assay to test chemotherapeutic effects in tissue.

7 Jul 2020

Purdue-affiliated medical device company raises over $1.5 million to scale up business

SpeechVive Inc. announced Tuesday (July 7) the completion of a convertible note that will provide the necessary resources to begin scaling the business.

7 Jul 2020

New 'catch and kill' air filter can trap SARS-CoV-2 virus

Researchers from the University of Houston, in collaboration with others, have designed a "catch and kill" air filter that can trap the virus responsible for COVID-19, killing it instantly.

7 Jul 2020

Gene expression networks flag potential therapeutic targets for SARS-CoV-2

An international team of researchers from Canada, Australia, the Netherlands, and the United States has identified dozens of genes that could contribute to the pathology of coronavirus disease 2019 (COVID-19) and serve as potential therapeutic targets.

7 Jul 2020

NIH study: Long-acting form of HIV prevention drug more effective than daily oral pill

A pre-exposure prophylaxis (PrEP) regimen containing an investigational long-acting form of the HIV drug cabotegravir injected once every 8 weeks was more effective than daily oral Truvada at preventing HIV acquisition among cisgender men who have sex with men and transgender women who have sex with men in a clinical trial sponsored by the National Institutes of Health.

7 Jul 2020

Dopamine neurons regulate the internal decision-making process

In Indiana Jones and the Last Crusade, Indiana must choose his grail "wisely", as a poor choice spells instant death.

7 Jul 2020

Cerebrospinal fluid autoantibodies target the brain in some COVID-19 patients

A study conducted by German researchers has shown that the neurological symptoms observed in some patients with coronavirus disease 2019 (COVID-19) may be caused by autoantibodies targeting the brain.

7 Jul 2020

Researchers discover new mechanism to explain the effects of subcortical strokes

IBS researchers have discovered a new mechanism to explain the effects of subcortical strokes and a new possible therapeutic approach.

7 Jul 2020

Migrant workers contribute to the spread of COVID-19 in India’s villages

India's lockdown may have hastened spread of COVID-19 to rural areas as millions of migrant workers, trapped in the big cities, ended up being exposed to the virus — which they carried into their distant villages when finally allowed to return.

7 Jul 2020

Evolutionary snapshot reveals genetic stability of SARS-CoV-2

A multinational study currently available on the bioRxiv preprint server shows that in the early large genome of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) only a handful of amino acids are exchanged, implying a relatively low mutation rate and selection pressure.

7 Jul 2020

Surgical delay linked to increased risk in gastrointestinal malignancies, study finds

Early in the COVID-19 pandemic, widespread cancellations of electively-scheduled or "non-emergency" operations were implemented to free up hospital beds and conserve protective equipment for health care workers.

7 Jul 2020

Early life exposure to influenza shapes our susceptibility to future infections

Early infections of influenza A can help predict how the virus will affect people across different ages in the future and could impact the effectiveness of flu vaccines, says a new study published today in eLife.

7 Jul 2020

Woman's egg quality found to be dependent on important metabolic coenzyme

Increasing the levels of a chemical found in all human cells could boost a woman's fertility and help select the best eggs for IVF, according to University of Queensland research.

7 Jul 2020

Desk-based jobs associated with lower risk of poor cognition

People who work in jobs that require less physical activity - typically office and desk-based jobs - are at a lower risk of subsequent poor cognition than those whose work is more physically active, suggests new research from the University of Cambridge.

7 Jul 2020

Early life BMI linked to cardiovascular disease signs at 11-12 years

Toddlers who were obese or overweight show concerning signs of cardiovascular disease at 11-12 years of age, according to a new study led by the Murdoch Children's Research Institute (MCRI).

7 Jul 2020

Fathers' social media posts can predict risk of postpartum depression

Fathers' prepartum social media posts can predict their risk of postpartum depression. A predictive model based on machine learning is described in the peer-reviewed journal Cyberpsychology, Behavior, and Social Networking.

7 Jul 2020

Inadequate nighttime sleep alters children's emotional health

In a new study published in the Journal of Child Psychology and Psychiatry, Candice Alfano, University of Houston professor of psychology and director of the Sleep and Anxiety Center of Houston, reports the results from an innovative, experimental study showing inadequate nighttime sleep alters several aspects of children's emotional health.

7 Jul 2020

Boosting manganese levels during pregnancy could potentially reduce preeclampsia risk

An analysis of data from more than 1,300 women followed prospectively through pregnancy found that women with lower levels of the essential mineral manganese in early pregnancy were more likely to develop the serious high blood pressure syndrome called preeclampsia in late pregnancy, according to a new study led by researchers from Johns Hopkins Bloomberg School of Public Health.

7 Jul 2020

Unique photonic device could pave the way for a breakthrough in medical implants

Over the past few decades, medical technology seen various advances in terms of the scope and efficiency of implant devices.

7 Jul 2020

7 in 10 U.S. adults worry poor health will limit their life experiences, survey finds

Seven in 10 U.S. adults worry poor health will prevent them from doing all the things they'd like to do in life, according to a new survey from the American Heart Association and American Diabetes Association.

7 Jul 2020