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Enfortumab vedotin and pembrolizumab show major benefits for urothelial carcinoma patients

Urothelium is the term for the mucous membrane that lines the urinary tract. This includes the renal pelvis, ureter, urinary bladder and the upper part of the urethra. In the vast majority of cases, urothelial carcinomas grow in the bladder (bladder carcinoma).

4 Apr 2025

Triple therapy reduces tumor burden and improves survival in glioblastoma models

A new research paper was published in Oncotarget, Volume 16, on March 27, 2025, titled "Imipridones ONC201/ONC206 + RT/TMZ triple (IRT) therapy reduces intracranial tumor burden, prolongs survival in orthotopic IDH-WT GBM mouse model, and suppresses MGMT."

4 Apr 2025

CRISPR tool unveils genetic drivers of blood cell maturation

Collaborative research led by investigators at Dana-Farber/Boston Children's Cancer and Blood Disorders Center defines a novel approach to understanding how certain proteins called transcription factors determine which genetic programs will drive cell growth and maturation.

4 Apr 2025

Cornell researchers discover brain mechanisms behind psilocybin's effects

Psilocybin is the active ingredient that gives so-called "magic mushrooms" their hallucinogenic kick. It also has a therapeutic potential for treating depression.

4 Apr 2025

New study reveals hidden spread of C. diff in intensive care units

One of the most common health care-associated infections spreads within intensive care units (ICUs) more than three times more than previously thought, new research has found.

4 Apr 2025

Pancreatic cells show epigenetic marks before cancerous transformation

Johns Hopkins Medicine scientists say they have found a pattern of so-called epigenetic "marks" in a transition state between normal and pancreatic cancer cells in mice, and that the normal cells may keep at least a temporary "memory" of those cancer-linked marks.

4 Apr 2025

Older adults embrace digital health portals despite billing concerns

When today's older adults were growing up, the only way to get information to your doctor or their clinic was a phone call. And getting more than a simple answer probably meant going in for an appointment.

4 Apr 2025

Small molecular shifts can drastically alter encephalitis virus behavior

New research shows how small shifts in the molecular makeup of a virus can profoundly alter its fate. These shifts could turn a deadly pathogen into a harmless bug or supercharge a relatively benign virus, influencing its ability to infect humans and cause dangerous outbreaks.

4 Apr 2025

Exposure to wildfire smoke raises mental health visits to emergency departments

Exposure to fine particulate air pollution (PM2.5) from wildfire smoke was associated with increased visits to emergency departments (ED) for mental health conditions, according to a new study led by researchers at Harvard T.H. Chan School of Public Health.

4 Apr 2025

Unique sound stimulation technology can relieve symptoms of motion sickness

A research group led by Takumi Kagawa and Masashi Kato at Nagoya University Graduate School of Medicine has discovered that using "a unique sound stimulation technology"-a device that stimulates the inner ear with a specific wavelength of sound-reduces motion sickness.

4 Apr 2025

ACP issues Best Practice Advice on cannabis for chronic pain management

The American College of Physicians (ACP) has issued Best Practice Advice for clinicians whose patients are considering or using cannabis or cannabinoids for management of chronic, noncancer pain.

4 Apr 2025

Uncommon ovarian tumors detected in a single patient

A new case report was published in Oncoscience's Volume 12 on March 31, 2025, titled "Cystadenofibroma and contralateral collision lesions: A unique ovarian case report."

4 Apr 2025

Cedars-Sinai study reveals distinct roles for AI and physicians in virtual care

Do physicians or artificial intelligence (AI) offer better treatment recommendations for patients examined through a virtual urgent care setting? A new Cedars-Sinai study shows physicians and AI models have distinct strengths.

4 Apr 2025

Two plant-based diets linked to similar survival benefits and low environmental impact

Two plant-based diets were associated with similar survival benefits and low environmental impact, according to research presented today at ESC Preventive Cardiology 2025, a scientific congress of the European Society of Cardiology (ESC).

4 Apr 2025

New insights into bacterial defense mechanisms could help combat antibiotic resistance

Antibiotic resistance is a global health challenge that could overtake cancer mortality within a few decades.

4 Apr 2025

Novel NK cell therapy shows strong response in lymphoma patients

A novel cell therapy approach using cord blood-derived natural killer (NK) cells pre-complexed with AFM13, or acimtamig, a CD30/CD16A bispecific antibody, was safe and generated strong response rates for patients with refractory CD30-positive lymphomas, according to a new study from The University of Texas MD Anderson Cancer Center.

4 Apr 2025

Groundbreaking national initiative in Sweden aims to connect research with healthcare

A groundbreaking national initiative, Precision Omics Initiative Sweden (PROMISE), aims to connect research with healthcare and establish Sweden as a world leader in data-driven precision medicine.

4 Apr 2025

Singapore launches a strategic new standard to strengthen disinfectant market

As public awareness of hygiene and infection control grows in a post-pandemic world, Singapore has launched a strategic national standard to strengthen public health and industry accountability in the rapidly expanding disinfectant market.

4 Apr 2025

How schools used pandemic relief funds to identify and serve students experiencing homelessness

University of Michigan research sheds new light on how school districts used their share of $800 million in pandemic relief funds that were specifically dedicated to the education of children and youth experiencing homelessness.

4 Apr 2025

Early warning signs may help prevent sudden arrhythmic death syndrome

Recognizing and detecting the signs that commonly precede sudden arrhythmic death syndrome (SADS) may help to prevent premature deaths, according to research presented today at ESC Preventive Cardiology 2025, a scientific congress of the European Society of Cardiology (ESC).

4 Apr 2025