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FDA approves antibacterial drug to treat travelers' diarrhea

The U.S. Food and Drug Administration today approved Aemcolo (rifamycin), an antibacterial drug indicated for the treatment of adult patients with travelers' diarrhea caused by noninvasive strains of Escherichia coli (E. coli), not complicated by fever or blood in the stool.

17 Nov 2018

In-hospital mortality higher among patients with drug-resistant infections

In one of the largest studies to measure the burden of antibiotic resistance in a low- or middle-income country, researchers at the Center for Disease Dynamics, Economics & Policy report that in-hospital mortality is significantly higher among patients infected with multi-drug resistant or extensively drug resistant pathogens including Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae and Acinetobacter baumannii.

17 Nov 2018

UCLA biologists uncover how head injuries can lead to serious brain disorders

UCLA biologists have discovered how head injuries adversely affect individual cells and genes that can lead to serious brain disorders.

17 Nov 2018

Static and dynamic physical activities offer varying protection against heart disease

While it is well known that physical activity is important for heart health, neither research nor recommendations consistently differentiate between the benefits of different types of physical activity.

17 Nov 2018

Obesity significantly increases risk of Type 2 diabetes and coronary artery disease

A Cleveland Clinic genetic analysis has found that obesity itself, not just the adverse health effects associated with it, significantly increases the risk of Type 2 diabetes and coronary artery disease. The paper was published today in the Journal of the American Medical Association Network Open.

17 Nov 2018

New first-line treatment for peripheral T-cell lymphoma approved by FDA

The U.S. Food and Drug Administration today expanded the approved use of Adcetris (brentuximab vedotin) injection in combination with chemotherapy for adult patients with certain types of peripheral T-cell lymphoma.

16 Nov 2018

Personalized scheduling of radiotherapy using genetic data could reduce side effects

A new clinical study led by the University of Leicester and conducted in the HOPE clinical trials facility at Leicester's Hospitals has revealed the pivotal role that changing the time of day that a patient receives radiotherapy could play in altering radiotherapy toxicity.

16 Nov 2018

EMA recommends first all-oral treatment to tackle deadly sleeping sickness

The European Medicines Agency's Committee for Medicinal Products for Human Use has adopted a positive scientific opinion of fexinidazole, the first all-oral treatment that has been shown to be efficacious for both stages of sleeping sickness.

16 Nov 2018

Gene editing could be used to halt kidney disease in patients with Joubert syndrome

For the first time scientists have identified how to halt kidney disease in a life-limiting genetic condition, which may pave the way for personalized treatment in the future.

16 Nov 2018

American Cancer Society study links social isolation to higher mortality risk

A large American Cancer Society study links social isolation with a higher risk of death from all causes combined and heart disease for all races studied, and with increased cancer mortality in white men and women.

16 Nov 2018

Long term exposure to road traffic noise linked with greater obesity risk

Long term exposure to road traffic noise is associated with increased risk of obesity. This was the conclusion of a study involving the participation of the Barcelona Institute for Global Health, a research center supported by the "la Caixa" Banking Foundation. The study has been published in Environment International.

16 Nov 2018

Infant gut microbes altered by mother's obesity may increase risk for future disease

Infant gut microbes altered by their mother's obesity can cause inflammation and other major changes within the baby, increasing the risk of obesity and non-alcoholic fatty liver disease later in life, according to researchers at the University of Colorado Anschutz Medical Campus.

16 Nov 2018

Sucking your baby’s pacifier could improve their health

A new study has found that sucking on a baby's pacifier is linked to lower IgE levels, an antibody that is increased in allergies and asthma.

16 Nov 2018

Autism linked to prolonged connection between brain regions

Researchers have discovered that the symptoms seen in autism may be linked to how regions of the brain communicate.

16 Nov 2018

Humans play key role in distribution and transmission of Bartonella bacteria

Bartonella bacteria are disease-causing, blood-borne pathogens found in various mammal species. A study in PLOS Neglected Tropical Diseases by Hannah Frank and colleagues at Stanford University, California suggests that humans play an important role in disease risk, infection patterns, and distribution of Bartonella, advancing current understanding of Bartonella’s evolutionary history and how the bacteria may be transmitted between humans and other animal species.

16 Nov 2018

Researchers identify LZTR1 as evolutionarily conserved component of RAS pathway

Mutations in RAS proteins initiate many of the most aggressive tumors, and the search for pharmacological inhibitors of these proteins has become a priority in the battle against cancer. Michail Steklov, Francesca Baietti, and colleagues from the Anna Sablina lab identified LZTR1 as an evolutionarily conserved component of the RAS pathway.

16 Nov 2018

FIND explores new diagnostic assays for confirmatory HCV diagnosis in community settings

The Foundation for Innovative New Diagnostics today announced awards to support the development, manufacture and feasibility testing of two prototype hepatitis C virus core antigen immunoassays for confirmatory HCV diagnosis at the point of care.

16 Nov 2018

Mechanisms that govern HIV latency differ in the gut and blood, finds study

Mechanisms that govern HIV transcription and latency differ in the gut and blood, according to a study published November 15 in the open-access journal PLOS Pathogens by Steven Yukl of San Francisco Veterans Affairs Medical Center and the University of California, San Francisco, and colleagues.

16 Nov 2018

Group of students aim to improve malaria diagnosis using old smartphones

Over 212 million cases of malaria are reported annually, with the majority of incidences occuring in Sub-Saharan Africa. However, a lack of medical resources means blood sample analysis is often delayed, leading to errors and ultimately high mortality rates.

16 Nov 2018

Drug used to treat dizziness may slow down growth of triple-negative breast cancer

Screening Food and Drug Administration approved compounds for their ability to stop cancer growth in the lab led to the finding that the drug flunarizine can slow down the growth of triple-negative breast cancer in an animal model of the disease.

16 Nov 2018

Medical News

FDA approves antibacterial drug to treat travelers' diarrhea

In-hospital mortality higher among patients with drug-resistant infections

UCLA biologists uncover how head injuries can lead to serious brain disorders

Static and dynamic physical activities offer varying protection against heart disease

Obesity significantly increases risk of Type 2 diabetes and coronary artery disease

New first-line treatment for peripheral T-cell lymphoma approved by FDA

Personalized scheduling of radiotherapy using genetic data could reduce side effects

EMA recommends first all-oral treatment to tackle deadly sleeping sickness

Gene editing could be used to halt kidney disease in patients with Joubert syndrome

American Cancer Society study links social isolation to higher mortality risk

Long term exposure to road traffic noise linked with greater obesity risk

Infant gut microbes altered by mother's obesity may increase risk for future disease

Sucking your baby’s pacifier could improve their health

Autism linked to prolonged connection between brain regions

Humans play key role in distribution and transmission of Bartonella bacteria

Researchers identify LZTR1 as evolutionarily conserved component of RAS pathway

FIND explores new diagnostic assays for confirmatory HCV diagnosis in community settings

Mechanisms that govern HIV latency differ in the gut and blood, finds study

Group of students aim to improve malaria diagnosis using old smartphones

Drug used to treat dizziness may slow down growth of triple-negative breast cancer

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

Membrane proteins in focus: Turning high-risk targets into routine workflows

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