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ARPP21 gene mutation could be the cause of ALS

Researchers from the Neuromuscular Diseases Group and the Dementia Neurobiology Group of the Sant Pau Research Institute (IR Sant Pau) and the Memory Unit of the Sant Pau Hospital, led by neurologist Dr. Ricard Rojas-García, have identified a new mutation in the ARPP21 gene that could be the cause of Amyotrophic Lateral Sclerosis (ALS), a devastating neurodegenerative disease.

11 Jul 2024

Cornell researchers develop advanced urine filtration system for astronauts

Astronauts on spacewalks famously have to relieve themselves inside their spacesuits. Not only is this uncomfortable for the wearer and unhygienic, it is also wasteful, as – unlike wastewater on board the International Space Station (ISS) – the water in urine from spacewalks is not recycled.

11 Jul 2024

Light-activated drugs: A revolutionary approach in neuropathic pain treatment

Light can be used to activate drugs in specific parts of the body through photopharmacology.

11 Jul 2024

Burning ammonia for maritime fuel could lead to devastating public health impacts

As container ships the size of city blocks cross the oceans to deliver cargo, their huge diesel engines emit large quantities of air pollutants that drive climate change and have human health impacts.

11 Jul 2024

Unveiling late-onset combined immunodeficiency in patients with 18q del syndrome

Chromosome 18q deletion (18q del) syndromeis a rare genetic condition disorder, affecting approximately 1 in 40,000 to 55,000 individuals, caused by the deletion of genetic material on the long arm of chromosome 18.

11 Jul 2024

Researchers discover a new mechanism of resistance to KRAS inhibitors in pancreas cancer

Mutations in the KRAS gene are the primary driver of pancreatic cancer. A new class of drugs known as KRAS inhibitors is showing initial promise in clinical trials, but many tumors quickly develop resistance to the treatment.

11 Jul 2024

Nicotine absorption is much lower from second-hand vaping than from second-hand smoking

Children exposed to vaping indoors absorb less than one seventh the amount of nicotine as children who are exposed to indoor smoking, but more than those exposed to neither, according to a new study led by UCL researchers.

11 Jul 2024

Study: 40% of cancer cases in the U.S. attributable to modifiable risk factors

A new study led by researchers at the American Cancer Society (ACS) finds four in 10 cancer cases and about one-half of all cancer deaths in adults 30 years old and older in the United States (or 713,340 cancer cases and 262,120 cancer deaths in 2019) could be attributed to modifiable risk factors, including cigarette smoking, excess body weight, alcohol consumption, physical inactivity, diet, and infections.

11 Jul 2024

New study reveals the genetic cause of Parkinson's disease

According to Science Alert, neuroscientists from Johns Hopkins University have recently discovered a new treatment for Parkinson's disease using an FDA-approved cancer drug.

11 Jul 2024

The 16-month milestone: Toddlers engage more brain regions for cognitive skills

Toddlers engage more regions of their brains around 16-months to help them develop important cognitive skills enabling them to follow simple instructions and control impulses.

11 Jul 2024

Lipidomics reveals health benefits of switching to plant-based fats

Switching from a diet high in saturated animal fats to one rich in plant-based unsaturated fats affects the fat composition in the blood, which in turn influences long-term disease risk.

11 Jul 2024

Kobe University unveils key protein variants in exercise and weight loss

Some people lose weight slower than others after workouts, and a Kobe University research team found a reason.

11 Jul 2024

Distinct T-cell signatures identified in children with type 1 diabetes

A study conducted at the University of Eastern Finland found distinct signatures in CD8-positive T cells in blood samples from children with newly diagnosed type 1 diabetes and in autoantibody-positive children who later developed type 1 diabetes.

11 Jul 2024

CD22-targeted CAR-T therapy shows promising results in relapsed large B-cell lymphoma

CAR-T cell therapy, which targets a specific protein on the surface of cancer cells, causes tumors to shrink or disappear in about half of patients with large B-cell lymphoma who haven't experienced improvement with chemotherapy treatments.

11 Jul 2024

Optimizing influenza vaccine strategies with nanoparticle immunization

To offer cross-protection against diverse influenza virus variants, nanoparticle vaccines can produce pivotal cellular and mucosal immune responses that enhance vaccine efficacy and broaden protection, according to a study by researchers in the Institute for Biomedical Sciences at Georgia State University.

11 Jul 2024

Prime editing offers promising path to permanent treatment for cystic fibrosis

Cystic fibrosis is one of the most common genetic disorders, causing thick mucus build-up in the lungs and other parts of the body, breathing problems, and infection.

11 Jul 2024

Loneliness can have greater negative impact on memory than social isolation

About a third of Canadians feel lonely, and a study from the University of Waterloo shows it has a greater negative impact on memory than even social isolation, though both present a significant risk to the aging population.

11 Jul 2024

Novel model could predict cognitive decline in patients with mild cognitive impairment due to Alzheimer's

Amsterdam UMC's Alzheimer Centre has developed a prediction model that can predict cognitive decline in patients with mild cognitive impairment or mild dementia due to Alzheimer's disease.

11 Jul 2024

Novel Co-STAR cells show promise in targeting and eradicating cancer

Using genetic engineering techniques, investigators at the Johns Hopkins Kimmel Cancer Center and its Ludwig Center, the Lustgarten Laboratory and Bloomberg~Kimmel Institute for Cancer Immunotherapy have designed a novel type of cell to recognize and fight cancer.

11 Jul 2024

Comprehensive study of telemedicine adoption in U.S. hospitals reveals progress and challenges

A new study led by Michigan State University researchers shows a significant increase in telemedicine services offered by U.S. hospitals from 2017 to 2022, while also highlighting persistent barriers to its full implementation.

11 Jul 2024