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Fish's retina inspired autofocus contact lens could benefit presbyopia patients

Making the most of the low light in the muddy rivers where it swims, the elephant nose fish survives by being able to spot predators amongst the muck with a uniquely shaped retina, the part of the eye that captures light. In a new study, researchers looked to the fish's retinal structure to inform the design of a contact lens that can adjust its focus.

15 Mar 2016

New drug could transform treatment of metastatic triple negative breast cancer

A team of investigators from Houston Methodist Research Institute may have transformed the treatment of metastatic triple negative breast cancer by creating the first drug to successfully eliminate lung metastases in mice.

15 Mar 2016

Exercise programme reduces symptoms among young adults with first-episode psychosis

An exercise programme devised by researchers at the University of Manchester has dramatically reduced symptoms among young people with first-episode psychosis.

15 Mar 2016

Excessive fat accumulation in lower extremities of children linked to insulin resistance, metabolic disorders

Children with a severe type of spina bifida called myelomeningocele have a high prevalence of obesity and excess fat accumulation in their lower extremities. In a study designed to assess bone, muscle and fat tissue distribution in the lower legs of children with this disease, researchers at Children's Hospital Los Angeles determined that this excess fat tissue is within the muscle boundary (muscle-associated) rather than subcutaneous.

15 Mar 2016

Scientists find surprising link between iPS cell reprogramming, blood cell formation and cancer

The ability to reprogram cells has revolutionized stem cell research with major implications for almost all fields of modern biology. A decade ago Shinya Yamanaka described a procedure that revolutionized stem cell biology. Using a genetic trick that introduces a cocktail of four genes into cultured cells from human biopsies, he was able to generate induced pluripotent stem cells (iPS) from mature skin or blood cells

15 Mar 2016

Combination drug therapy may stop KRAS-mediated lung adenocarcinoma

Researchers on Mayo Clinic's Florida campus have shut down one of the most common and lethal forms of lung cancer by combining the rheumatoid arthritis drug auranofin with an experimental targeted agent.

15 Mar 2016

Alcohol consumption may increase risk for breast cancer

A University of Houston researcher and his team have discovered an important link between alcohol and breast cancer by identifying a cancer-causing gene triggered by alcohol

15 Mar 2016

Researchers discover potentially-pathogenic bacteria in water supply pipes

The human microbiome, a diverse collection of microorganisms living inside us and on our skin, has attracted considerable attention for its role in a broad range of human health issues. Now, researchers are discovering that the built environment also has a microbiome, which includes a community of potentially-pathogenic bacteria living inside water supply pipes.

15 Mar 2016

Anticancer drug restores hearing in neurofibromatosis patients

In a small clinical study with an anticancer drug that halts blood vessel growth, a handful of people with neurofibromatosis type 2 (NF2) and hearing loss had restoration of hearing.

15 Mar 2016

Drugs to help energy-starved photoreceptors offers new avenue for treating AMD , MacTel

New research from Boston Children's Hospital could potentially change how doctors approach two blinding diseases: 'Wet' age-related macular degeneration (AMD), the leading cause of blindness in the elderly, and macular telangiectasia (MacTel).

15 Mar 2016

New chemical probe could tag cells for detection by MRI

The need to non-invasively "see" and track cells in living persons is indisputable - a boon to both research and development of future therapies. Emerging treatments using stem cells and immune cells are poised to most benefit from cell tracking, which would visualize their behavior in the body after delivery. Clinicians require such data to speed these cell treatments to patients.

15 Mar 2016

One-fourth of seniors acquire new superbugs during hospital stay

One in four seniors is bringing along stowaways from the hospital to their next stop: superbugs on their hands.Moreover, seniors who go to a nursing home or other post-acute care facility will continue to acquire new superbugs during their stay, according to findings made by University of Michigan researchers published today in a JAMA Internal Medicine research letter.

15 Mar 2016

Combining photoimmunotherapy and gene transduction effective against elusive gastric cancer cells

Researchers report photoimmunotherapy to be effective against elusive gastric cancer cells following transduction with the gene that expresses the extracellular domain protein of HER2. The results are published in the journal Small Molecule Therapeutics in February 2016.

15 Mar 2016

ZYTIGA plus prednisone provides overall survival benefit in men with early and less aggressive mCRPC

Janssen-Cilag International NV today announced that data from a post-hoc analysis of the Phase 3 COU-AA-302 trial showed that ZYTIGA (abiraterone acetate) plus prednisone provided an 11.8 months overall survival (OS) benefit (53.6 months vs 41.8 months; HR = 0.61 [95% CI, 0.43-0.87]; p = 0.0055), compared to an active control of placebo plus prednisone, in men with early and less aggressive chemotherapy-naïve metastatic castration-resistant prostate cancer (mCRPC).

15 Mar 2016

Advion introduces new metal catalyst reaction monitoring technique for CMS product line

Advion, Inc., a leading systems and consumables developer for the life sciences industry, announced during this week's 251st American Chemical Society National Meeting & Exposition in San Diego, California the introduction of a breakthrough sample introduction technique for its line of expression compact mass spectrometers (CMS).

15 Mar 2016

Boston Scientific announces European launch of LithoVue Single-Use Digital Flexible Ureteroscope

Marlborough, Mass. Boston Scientific Corporation today announced the European launch of the LithoVue Single-Use Digital Flexible Ureteroscope for minimally invasive endoscopic procedures to diagnose and treat stones and other conditions of the kidney, ureter and bladder.

15 Mar 2016

Preoperative lapatinib plus trastuzumab elicits response in HER2-positive breast cancer

Addition of lapatinib to trastuzumab improves responses in women with newly diagnosed, HER2-positive breast cancer who receive the combination prior to undergoing surgery, suggests research.

14 Mar 2016

Researchers aim to design a better male contraceptive pill

Women can choose from a wide selection of birth control methods, including numerous oral contraceptives, but there's never been an analogous pill for men. That's not for lack of trying: For many years, scientists have attempted to formulate a male pill. Finally, a group of researchers has taken a step toward that goal by tweaking some experimental compounds that show promise.

14 Mar 2016

Liposomes can be potential candidates for drug delivery to constricted coronary arteries

Liposomes are currently used as drug delivery vehicles but recognized by the immune system. Scientists from the universities of Basel and Fribourg have shown that special artificial liposomes do not elicit any reaction in human and porcine sera as well as pigs.

14 Mar 2016

Researchers identify potential drug target in skin for itchy feeling

No matter the trigger -- bug bites, a medication side-effect or an itchy wound -- the urge to scratch can be a real pain. Researchers at the Duke University Medical Center have identified a potential drug target in the skin for that itchy feeling.

14 Mar 2016

Medical News

Fish's retina inspired autofocus contact lens could benefit presbyopia patients

New drug could transform treatment of metastatic triple negative breast cancer

Exercise programme reduces symptoms among young adults with first-episode psychosis

Excessive fat accumulation in lower extremities of children linked to insulin resistance, metabolic disorders

Scientists find surprising link between iPS cell reprogramming, blood cell formation and cancer

Combination drug therapy may stop KRAS-mediated lung adenocarcinoma

Alcohol consumption may increase risk for breast cancer

Researchers discover potentially-pathogenic bacteria in water supply pipes

Anticancer drug restores hearing in neurofibromatosis patients

Drugs to help energy-starved photoreceptors offers new avenue for treating AMD , MacTel

New chemical probe could tag cells for detection by MRI

One-fourth of seniors acquire new superbugs during hospital stay

Combining photoimmunotherapy and gene transduction effective against elusive gastric cancer cells

ZYTIGA plus prednisone provides overall survival benefit in men with early and less aggressive mCRPC

Advion introduces new metal catalyst reaction monitoring technique for CMS product line

Boston Scientific announces European launch of LithoVue Single-Use Digital Flexible Ureteroscope

Preoperative lapatinib plus trastuzumab elicits response in HER2-positive breast cancer

Researchers aim to design a better male contraceptive pill

Liposomes can be potential candidates for drug delivery to constricted coronary arteries

Researchers identify potential drug target in skin for itchy feeling

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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