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iTeos Therapeutics, Pfizer form strategic collaboration for cancer immunotherapeutics

iTeos Therapeutics SA announced today a strategic collaboration with Pfizer Inc. pursuant to which iTeos will license to Pfizer rights to iTeos' pre-clinical compounds targeting Indoleamine 2,3-dioxygenase (IDO1) and Tryptophan 2,3-dioxygenase (TDO2). Pfizer will be responsible for the development and commercialization of IDO1 and TDO2 drug candidates.

8 Dec 2014

Researchers gain new insights into potential treatment for Alzheimer's disease

It is estimated that about 35 million people worldwide currently suffer from dementia and it is expected that the number will increase to 135 million by the year 2050. The disease is already one of the most common health problems in the elderly, which is why experts predict that the numbers of people affected will increase over time.

8 Dec 2014

Saint-Gobain Seals provides OmniSeal® spring-energized seals to OEM’s in the medical miniature motor market

Saint-Gobain Seals continues to provide their dynamic OmniSeal® spring-energized seals to OEM’s in the medical miniature motor market, which allows them to provide a well-balanced sealed motor and an added sense of security to their surgical tool OEM’s. The medical market has been growing quite rapidly with the need for more portable applications that are unobtrusive and efficient but still powerful.

8 Dec 2014

Most elderly women with early-stage breast cancer still receive radiation therapy despite less benefit

Women over the age of 70 who have certain early-stage breast cancers overwhelmingly receive radiation therapy despite published evidence that the treatment has limited benefit, researchers at Duke Medicine report.

8 Dec 2014

Corrective information can successfully reduce false beliefs about flu vaccines

With health systems in the U.S., U.K., and around the world trying to increase vaccination levels, it is critical to understand how to address vaccine hesitancy and counter myths about vaccine safety. A new article in the journal "Vaccine" concludes, however, that correcting myths about vaccines may not be the most effective approach to promoting immunization among vaccine skeptics.

8 Dec 2014

Weight-loss surgery may reduce lower urinary tract symptoms

Metabolic syndrome is linked with an increased frequency and severity of lower urinary tract symptoms, but weight loss surgery may lessen these symptoms. The findings, which come from two studies published in BJU International, indicate that urinary problems may be added to the list of issues that can improve with efforts that address altered metabolism.

8 Dec 2014

Subsets of cells drive spread of multiple myeloma

Although it is among the most highly metastatic of all cancers, multiple myeloma is driven to spread by only a subset of the myeloma cells within a patient's body, researchers at Dana-Farber Cancer Institute have found in a study presented at the annual meeting of the American Society of Hematology.

8 Dec 2014

Oral targeted drug shows encouraging activity in patients with relapsed or resistant AML

An oral targeted drug has shown encouraging activity and tolerable side effects in patients with treatment-resistant or relapsed acute myelogenous leukemia (AML) - a poor-prognosis group with few options - report investigators from Dana-Farber Cancer Institute and M.D. Anderson Cancer Center.

8 Dec 2014

Two-drug combination may be effective for patients with higher-risk forms of MDS and AML

A phase two study that investigated the potential of the drugs azacitidine (AZA) and lenalidomide (LEN), demonstrated that the two therapies in combination may be an effective frontline treatment regimen for patients with higher-risk forms of myelodysplastic syndrome and acute myeloid leukemia.

8 Dec 2014

Baylor-led researchers identify gene linked to familial glioma

An international consortium of researchers led by Baylor College of Medicine has identified for the first time a gene associated with familial glioma (brain tumors that appear in two or more members of the same family) providing new support that certain people may be genetically predisposed to the disease.

8 Dec 2014

Adolescent and young adult patients with ALL fare better with high-intensity pediatric protocols

Results from a large, prospective clinical trial add to mounting evidence that adolescent and young adult patients--aged 16 to 39 with acute lymphoblastic leukemia (ALL)--tend to fare better when treated with high-intensity pediatric protocols than previous patients who were treated with standard adult regimens.

8 Dec 2014

New type of cancer therapy shows promise in patients with advanced leukemia

A new type of cancer therapy that targets an oncometabolite produced dramatic results in patients with advanced leukemia in an early-phase clinical trial. The study, led by Eytan M. Stein, MD, a medical oncologist at Memorial Sloan Kettering Cancer Center, was presented today at the 56th Annual Meeting of the American Society of Hematology.

8 Dec 2014

AbbVie reports results from venetoclax Phase 2 clinical trial in AML at ASH 2014

AbbVie presented during an oral presentation at the American Society of Hematology's 56th Annual Meeting new results from a Phase 2 study of investigational compound venetoclax (ABT-199/GDC-0199) in patients with acute myelogenous leukemia (AML). AML is an aggressive and deadly type of blood cancer, in which the body produces too many of a specific type of white blood cell (myeloblast), which can crowd out healthy blood cells.

8 Dec 2014

New trial shows efficacy of PrimiCell product on muscle repair

BioAdaptives, Inc. announced results of the recently completed in vivo trial showing the efficacy of its PrimiCell product on muscle repair.

8 Dec 2014

Continuous glucose monitoring (CGM) mobile communications: an interview with Jorge Valdes

Type 1 diabetes is a complex condition to manage. It requires continuous, around the clock monitoring of blood glucose levels, which change repeatedly throughout the day and night.

7 Dec 2014

Novel targeted therapies and treatment combinations for leukemia

Recognizing that leukemia cannot be conquered with a "one-size-fits-all" approach, researchers are pursuing novel targeted therapies and combinations of existing treatment regimens with new agents for patient populations with historically poor prognoses, according to data presented today during the 56th American Society of Hematology Annual Meeting and Exposition.

7 Dec 2014

Novo Nordisk reports positive data from Novoeight phase 3 study in people with haemophilia A

Today, Novo Nordisk announced a new analysis of phase 3 data demonstrating people with haemophilia A who had the highest annualised bleeding rate (ABR) during initial treatment with Novoeight (Antihemophilic Factor [Recombinant]) showed the largest reduction in bleeding over the duration of treatment.

From Novo Nordisk 7 Dec 2014

New study finds that military culture enables use of tobacco for stress relief

Military culture perpetuates the notion that using tobacco provides stress relief, a new study in the American Journal of Health Promotion finds. But other stress relievers, such as exercise or taking meditation breaks, could be more valuable and effective than smoking breaks and avoid the health risks of tobacco.

7 Dec 2014

Breakthrough therapy shows promise in resistant forms of Hodgkin lymphoma

A therapy that liberates the immune system to attack cancer cells drove Hodgkin lymphoma (HL) into complete or partial remission in fully 87 percent of patients with resistant forms of the disease who participated in an early-phase clinical trial, investigators at Dana-Farber Cancer Institute and partnering institutions report in a study published today in the New England Journal of Medicine and simultaneously presented at the annual meeting of the American Society of Hematology in San Francisco.

7 Dec 2014

Having simultaneous chemotherapy and breast reconstruction after mastectomy may rise complications

Immediate breast reconstruction following mastectomy is becoming more prevalent. However, in breast cancer patients undergoing simultaneous chemotherapy, thrombotic complications can arise that can delay or significantly modify reconstructive plans. Outcomes of cases illustrating potential complications are published in the current issue of Annals of Medicine and Surgery.

7 Dec 2014

Medical News

iTeos Therapeutics, Pfizer form strategic collaboration for cancer immunotherapeutics

Researchers gain new insights into potential treatment for Alzheimer's disease

Saint-Gobain Seals provides OmniSeal® spring-energized seals to OEM’s in the medical miniature motor market

Most elderly women with early-stage breast cancer still receive radiation therapy despite less benefit

Corrective information can successfully reduce false beliefs about flu vaccines

Weight-loss surgery may reduce lower urinary tract symptoms

Subsets of cells drive spread of multiple myeloma

Oral targeted drug shows encouraging activity in patients with relapsed or resistant AML

Two-drug combination may be effective for patients with higher-risk forms of MDS and AML

Baylor-led researchers identify gene linked to familial glioma

Adolescent and young adult patients with ALL fare better with high-intensity pediatric protocols

New type of cancer therapy shows promise in patients with advanced leukemia

AbbVie reports results from venetoclax Phase 2 clinical trial in AML at ASH 2014

New trial shows efficacy of PrimiCell product on muscle repair

Continuous glucose monitoring (CGM) mobile communications: an interview with Jorge Valdes

Novel targeted therapies and treatment combinations for leukemia

Novo Nordisk reports positive data from Novoeight phase 3 study in people with haemophilia A

New study finds that military culture enables use of tobacco for stress relief

Breakthrough therapy shows promise in resistant forms of Hodgkin lymphoma

Having simultaneous chemotherapy and breast reconstruction after mastectomy may rise complications

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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