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Scientists reveal biochemical pathway responsible for manufacturing glycoalkaloids

In 1924, Science magazine reported on a fatal case of potato poisoning: James B. Matheney of Vandalia, Illinois, had gathered about one and a half bushels of tubers, which had turned green due to sunlight exposure.

1 Aug 2013

Scientists solve structure of infection tool used by Yersinia bacterium

Abdominal pain, fever, diarrhoea -- these symptoms could point to an infection with the bacterium Yersinia. The bacterium's pathogenic potential is based on a syringe-like injection apparatus called injectisome.

1 Aug 2013

Montreal scientists develop novel approach for scanning entire genome

Recent technological developments in genomics have revealed a large number of genetic influences on common complex diseases, such as diabetes, asthma, cancer or schizophrenia. However, discovering a genetic variant predisposing to a disease is only a first step. To apply this knowledge towards prevention or cure, including tailoring treatment to the patient's genetic profile -also known as personalized medicine - we need to know how this genetic variant affects health.

1 Aug 2013

Research identifies important mechanism behind bladder cancer

Bladder cancer is a common condition - an estimated 10,000 people are diagnosed with the disease each year in the UK. It is the seventh most common cancer in the UK, affecting men more than women.

1 Aug 2013

CBO: Administration's employer mandate delay estimated to cost $12 billion

The amount represents lost tax revenue and additional costs. The Congressional Budget Office also noted that about one million fewer people will get insurance from their employers in 2014 than they would have if the mandate had been implemented.

1 Aug 2013

Rheonix, Life Technologies sign joint development agreement for molecular testing platform

Rheonix, Inc., a developer of fully automated molecular testing solutions, and Life Technologies Corp., a global leader in the life sciences tools and diagnostic markets, have entered into a joint development agreement to introduce a molecular testing platform for their Applied Markets business.

1 Aug 2013

Cedars-Sinai physicist receives William D. Coolidge Award for pioneering work in radiation oncology

Benedick Fraass, PhD, FAAPM, FASTRO, FACR, received the highest honor from the American Association of Physicists in Medicine — the William D. Coolidge Award — for his distinguished career achievements in medical physics, including his pioneering work in radiation oncology.

1 Aug 2013

University of Iowa study links bigger lungs with improved survival for transplant patients

When it comes to lung transplants, bigger may be better. That's the main finding from a University of Iowa study, which found that oversized lungs lead to improved survival following lung transplants, particularly among patients receiving double-lung transplants.

1 Aug 2013

CCTA offers alternative means of improving triage of chest pain patients: Study

A study of two sets of 894 matched Emergency Department patients presenting with chest pain revealed that the use of coronary computed tomographic angiography led to fewer hospital admissions and shorter ED stays. According to lead researcher Michael Poon, MD, of Stony Brook University School of Medicine, the findings provide evidence that CCTA offers an alternative means of improving the triage of chest pain patients.

1 Aug 2013

Phase III trial shows afatinib offers clinical benefit to patients with EGFR mutation positive NSCLC

Afatinib has a novel mode of action and data has shown that it offers a clinical benefit to patients with a specific type of lung cancer, which we are further investigating in the extensive LUX-Lung clinical trial programme.

1 Aug 2013

Barton Healthcare Headlines app now available for use on Apple devices

Barton Associates, a leading national locum tenens physician and nurse practitioner staffing and recruiting company, announces the release of Barton Healthcare Headlines, a free mobile app now available in the Apple App Store for use on Apple devices, including iPhone, iPod touch, and iPad.

1 Aug 2013

Experts say action needed urgently to ensure India's new policy does not backfire

In an editorial published online today in BMJ, Johns Hopkins bioethicist Jeremy Sugarman and other experts warn that action is urgently needed to deal with possible unintended consequences of India's new policy protecting research participants.

1 Aug 2013

Viewpoints: GOP's shutdown vow; Peter Orszag defends rationale behind Medicare payment board

A dozen Republicans in the Senate have said they'd rather shut down the government than provide funding for the Patient Protection and Affordable Care Act, the 2010 healthcare reform law better known as Obamacare. Meanwhile, more than 60 Republicans in the House have called on their leadership to cut off all federal support for the law in the coming fiscal year. And they complain when President Obama doesn't hold up his end of the bargain? (7/30).

1 Aug 2013

Oxytocin hormone affects men and women differently, research finds

"The Love Hormone", Oxytocin affects men and women differently in social contexts- in men it improves the ability to identify competitive relationships whereas in women it facilitates the ability to identify kinship. "These findings are in agreement with previous studies on the social differences between the sexes: women tend to be more communal and familial in their behavior, whereas men are more inclined to be competitive and striving to improve their social status", said Prof. Simone Shamay-Tsoory from the Dept. of Psychology at the University of Haifa who led the research.

1 Aug 2013

Naked mole rat: A fitting model for finding novel ways to fight cancer

Mice and rats have long since been a standard animal model for cancer research, mainly due to their short lifespan of four years on average and high incidence of cancer. Naked mole rats however, are a mystery among mammals. This social tiny African subterranean rodent has a maximum lifespan exceeding 30 years and most surprisingly, is cancer-resistant.

1 Aug 2013

Transmembrane protein NG2 controls orientation of cell migration toward the wound

When the central nervous system is injured, oligodendrocyte precursor cells migrate to the lesion and synthesize new myelin sheaths on demyelinated axons. Scientists at the Institute of Molecular Cell Biology at Johannes Gutenberg University Mainz have now discovered that a distinct protein regulates the direction and movement of OPC toward the wound. The transmembrane protein NG2, which is expressed at the surface of OPCs and down-regulated as they mature to myelinating oligodendrocytes, plays an important role in the reaction of OPC to wounding.

1 Aug 2013

New approach could provide alternative treatment for chemotherapy-resistant breast cancer

A new way to target a breast cancer cells' appetite for over-indulging in sugar, that could provide an alternative treatment for chemotherapy resistant breast cancer, is being developed by Breast Cancer Campaign scientists at the University of Southampton.

1 Aug 2013

Researcher receives grant to study how exposure to social stress impacts the brain and behavior

Dr. Kim Huhman, a researcher in the Center for Behavioral Neuroscience at Georgia State University, has received a federal five-year, $1.8 million grant for research that may lead to improved strategies for treating and preventing mental health problems associated with exposure to social stress.

1 Aug 2013

Push to defund health law triggering fault lines among Republicans

The effort is gaining momentum among tea-party supporters and their Capitol Hill advocates, but some moderate GOP senators are taking a very different view.

1 Aug 2013

Finding could influence effectiveness of bone marrow transplants for late-stage leukemia

Eight years ago, two former Stanford University postdoctoral fellows, one of them still in California and the other at the Harvard Stem Cell Institute in Cambridge, began exchanging theories about why patients with leukemia stop producing healthy blood cells. What was it, they asked, that caused bone marrow to stop producing normal blood-producing cells?

1 Aug 2013

Medical News

Scientists reveal biochemical pathway responsible for manufacturing glycoalkaloids

Scientists solve structure of infection tool used by Yersinia bacterium

Montreal scientists develop novel approach for scanning entire genome

Research identifies important mechanism behind bladder cancer

CBO: Administration's employer mandate delay estimated to cost $12 billion

Rheonix, Life Technologies sign joint development agreement for molecular testing platform

Cedars-Sinai physicist receives William D. Coolidge Award for pioneering work in radiation oncology

University of Iowa study links bigger lungs with improved survival for transplant patients

CCTA offers alternative means of improving triage of chest pain patients: Study

Phase III trial shows afatinib offers clinical benefit to patients with EGFR mutation positive NSCLC

Barton Healthcare Headlines app now available for use on Apple devices

Experts say action needed urgently to ensure India's new policy does not backfire

Viewpoints: GOP's shutdown vow; Peter Orszag defends rationale behind Medicare payment board

Oxytocin hormone affects men and women differently, research finds

Naked mole rat: A fitting model for finding novel ways to fight cancer

Transmembrane protein NG2 controls orientation of cell migration toward the wound

New approach could provide alternative treatment for chemotherapy-resistant breast cancer

Researcher receives grant to study how exposure to social stress impacts the brain and behavior

Push to defund health law triggering fault lines among Republicans

Finding could influence effectiveness of bone marrow transplants for late-stage leukemia

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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