News Medical's "Thought Leaders" series is a selection of articles written by national and
international experts and trusted advisers in health and medicine. All the articles are
written by experts who have been invited as recognised leaders in their fields to provide
a "state of the art" contribution.
Prostate cancer development is associated with both inherited and acquired genetic alterations. More than 70 inherited genetic variants have been consistently identified in human DNA that may contribute to susceptibility or risk of prostate cancer.
This project was a secondary project that came out of a longitudinal cohort study that we've been conducting with the Windsor Village United Methodist Church in Houston Texas, which is a large, primarily African American mega-church with over fifteen hundred congregation members.
Allergic rhinitis is most commonly recognized as hay fever in the United Kingdom and it is due to the impact of an allergen, in the case of hay fever a pollen, setting off an inflammatory response in the lungs, causing typical symptoms...
A previous study in by Choi et al in the USA showed that people with a higher vitamin C intake have a lower risk of gout. There are also studies in healthy volunteers that suggest that vitamin C supplements reduce blood uric acid levels.
Ragweed is a dominant seasonal allergen in North America (~26% of US and North American population is allergic to this noxious weed which pollinates from early August to early October).
A whiplash injury is a common soft-tissue injury that may result in neck pain and other symptoms like headaches and arm pain.
While titanium is used widely for more conventional macro-scale medical devices (e.g. hip implants, dental implants, and cardiac pacemakers), its use for micro- and nano-scale devices has been limited thus far.
Mosquitoes can carry parasites and other organisms that cause deadly diseases such as malaria and dengue fever. So, protecting yourself against their bites is very important.
Thickening of the walls of the main arteries is the best indicator of poor cardiovascular health in healthy young children.
Exercise-induced bronchospasm (EIB) is defined as acute, transient airway narrowing that occurs in association with exercise. Exercise-induced bronchospasm can occur during or, more frequently, after exercise.
In clinical terms, depression is defined by the presence of a cluster of symptoms. The Diagnostic Manual used by many psychologists and psychiatrists cites nine symptoms of depression, of which five must be present for a two-week period.
Colorectal cancer is the third most common cancer in men and second in women, with over 1.2 million cases diagnosed worldwide in 2008.
Prednisone and non-steroidal anti-inflammatory drugs (NSAIDs) can be used for symptom control, but to prevent joint damage, we use disease-modifying anti-rheumatic drugs (DMARDs) including the cornerstone, methotrexate.
In cancer, mutations in proteins that control cell growth are common, leading to unrestrained cellular proliferation and tumor formation.
EPAC stands for exchange protein activated by cyclic AMP (cAMP). cAMP is an (among many) intracellular messenger molecule. cAMP is generated when certain hormones stimulate a cell by binding to their receptor, which is at the outside surface of the cell.
Prisoners overall have a very high rate of past or present injection drug use, which is a major risk factor for HCV infection due to repeated exposures to needles.
Acute pancreatitis is an inflammation of the pancreas which leads to leakage of pancreatic enzymes. Apart from certain drugs such as GLP-1 based therapies, the most common causes of pancreatitis are Gallstones and Alcohol use.
Rates of premature mortality in the UK have been falling steadily, but the pace of decline is not as fast as in many other high-income countries, such as Australia. In that sense, the UK lags behind.
MDR-TB is tuberculosis, a mycobacterial infection, that has developed resistance to two important and powerful first-line anti-TB drugs, INH and rifampin.
Nanogels are synthetic particles that can be used for drug delivery. They are approximately 100 nm to 200 nm in diameter, and are made from safe, biocompatible materials: a gel-like interior and a lipid exterior.