KYTHERA initiates proof-of-concept trial of its ATX-104 light-activated facial contouring agent

KYTHERA Biopharmaceuticals, Inc. (KYTHERA) today announced that it has initiated a first-in-human, proof-of-concept study evaluating the safety, tolerability, persistence and histological effects of ATX-104, a light-activated facial contouring agent.

“We are very excited to move ATX-104 into the clinic,” said Patricia Walker, MD, PhD, KYTHERA’s Chief Medical Officer. “In pre-clinical testing, KYTHERA’s proprietary photofiller demonstrated improved persistence, maintenance of shape and contourability – a combination of features not available in current dermal fillers. We see this as a next-generation filler platform that has the promise of dramatically expanding the landscape of possible aesthetic treatments.”

“The initiation of this ATX-104 trial marks an important milestone for KYTHERA. ATX-104 represents our third clinical stage product and the first based on our own Research programs,” said Keith Leonard, President and CEO of KYTHERA. “With the data from this initial proof-of-concept trial, we intend to evaluate worldwide partnership options for ATX-104.”


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