Bipolar disorder impacts life expectancy in the young

NewsGuard 100/100 Score

By Eleanor McDermid, Senior medwireNews Reporter

Research indicates that patients with bipolar disorder have a decreased life expectancy, with this being particularly pronounced in younger patients.

The life expectancy of bipolar patients was reduced by about 10 years, relative to the general population, report Lars Vedel Kessing (University of Copenhagen, Denmark) and colleagues, who describe the reduction as “substantial”, albeit “less than previously reported.”

Their study, based on data from Danish national registries, found the reduction in patients’ life expectancy to be slightly greater for men, at between 8.7 and 12.0 years, than for women, at 8.3 to 10.6 years.

The differences were largest for the youngest patients; women and men who had bipolar disorder at 15 years of age had, respectively, 10.4 and 12.8 years less life expectancy than their counterparts in the general population. At the age of 25 years, the differences were 10.6 and 12.0, respectively.

“This finding is in accordance with a number of publications suggesting a poor outcome among patients with early-onset bipolar disorder”, the team writes in Bipolar Disorders.

The difference in life expectancy between bipolar patients and the general population decreased with age, from 9.5 and 10.5 years among women and men, respectively, aged 35 years, to a corresponding 3.0 and 2.8 years at the age of 75 years.

The researchers believe this “may be partly due to the increased rate of suicide during the first years after onset of the illness”, but also to the cumulative long-term effects of factors such as low-grade inflammation, oxidative stress and unhealthy lifestyle factors among patients who develop bipolar disorder earlier in life.

“Clearly, this important area of research warrants further investigation”, they conclude.

Licensed from medwireNews with permission from Springer Healthcare Ltd. ©Springer Healthcare Ltd. All rights reserved. Neither of these parties endorse or recommend any commercial products, services, or equipment.

Comments

The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News Medical.
Post a new comment
Post

While we only use edited and approved content for Azthena answers, it may on occasions provide incorrect responses. Please confirm any data provided with the related suppliers or authors. We do not provide medical advice, if you search for medical information you must always consult a medical professional before acting on any information provided.

Your questions, but not your email details will be shared with OpenAI and retained for 30 days in accordance with their privacy principles.

Please do not ask questions that use sensitive or confidential information.

Read the full Terms & Conditions.

You might also like...
More than 3 billion people worldwide lived with a neurological condition in 2021, new study reports