When deciding on a liposome extrusion method, three major questions should be addressed. This article answers those questions about Genizer's tool set.
Image Credit: Genizer
Which pore size is required?
The chosen pore size will most likely determine the homogenizer used. A single homogenizer, for example, may produce liposomes as small as 20-30 nm, but any tool with extrusion capability offers a wider range of pore sizes.
Image Credit: Genizer
What power types are available?
The type of power available will also influence the selection of the homogenizer. For example, jacketed liposome extruders employ gas power, but an electric version is also available if a high-pressure homogenizer, with or without an extruder, is preferred. Genizer also provides manual options, such as the HandExtruder and HandGenizer.
Image Credit: Genizer
What sample size is being processed?
It is also crucial to evaluate the size of the sample(s) being processed. Genizer offers extrusion options ranging from 1 millimeter to factory scale, with a variety of sizes available.
Image Credit: Genizer
Each Genizer instrument has unique advantages based on the application, and the company's personnel is available to provide selection advice as required.
Extruder
- Variety of pore sizes
- Narrower size distribution
- More affordable
Homogenizer
- Faster
- Less likely to jam
Homogenizer & extruder
- Variety of pore sizes
- Faster
- Narrower size distribution
- Less likely to jam
Acknowledgments
Produced from materials originally authored by Genizer.
About Genizer
Genizer™, located in Technology Link in Greater Los Angeles, is dedicated to advancing homogenizer nanotechnology.
The company provides high-pressure homogenizers, liposome extruders, sanitary heat exchangers, diamond interaction chambers, and high-pressure gauges compatible with other brands of high-pressure homogenizers, pumps, and microfluidizers.
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