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AI model predicts cancer subtype, genetic mutations, and survival outcomes across 32 solid tumors

Researchers have developed a novel AI model that can analyze a routine whole histopathology image and simultaneously predict cancer subtype, specific genetic mutations, and survival outcomes across 32 different solid cancers rather than focusing on a single cancer type.

13 Aug 2026

Researchers identify genes that hinder CRISPR editing efficiency

Like a delivery driver navigating crowded city streets, a gene-therapy-toting lipid nanoparticle faces a gauntlet of potential detours on its journey toward a cell's nucleus.

13 Aug 2026

AI-based methods help uncover hidden roots of tumor metastasis

A cancerous tumor is not a single enemy. It is made up of many different cell populations that can behave in very different ways.

12 Aug 2026

Pediatric rheumatic diseases have unique genetic architecture compared to adults

Researchers from Children's Hospital of Philadelphia (CHOP) have found that pediatric-onset rheumatic and inflammatory diseases have distinct genetic architecture compared with adults.

12 Aug 2026

AI-augmented analysis sheds new light on Crohn's disease complications

Scientists have combined Artificial Intelligence (AI), genetics and gut microbiome analysis to shed new light on one of the most serious complications of Crohn's disease: intestinal fibrosis, the irreversible scarring of the bowel that often leads to surgery.

12 Aug 2026

Aging clock analysis identifies key genes in opioid dependence

A new research paper was published in Volume 18 of Aging on July 27, 2026, titled "Transcriptomic aging clock analysis identifies key genes in opioid dependence."

12 Aug 2026

Targeting single gene reverses developmental deficits in adult mice

Some of the symptoms of neurodevelopmental disorders (NDDs) such as autism spectrum disorder and epilepsy may result from dysfunction of certain neurons in the brain and their ability to change their properties in response to experiences-a process called experience-dependent plasticity.

12 Aug 2026

Molecular mapping reveals hidden cellular programs in heart transplant rejection

A new study that explores gene expression during heart transplant rejection marks a step forward for precision medicine approaches to treat organ rejection.

12 Aug 2026

Machine learning uses gene neighborhoods to identify harmful poultry bacteria

When it comes to identifying harmful bacteria, it helps to look at the company their genes keep.

12 Aug 2026

New machine learning model improves accuracy of prenatal genetic testing

Advances in genome sequencing are giving more families access to prenatal genetic testing and new information about an unborn baby's health, including whether genetic changes may link to a neurodevelopmental condition.

11 Aug 2026

Nocturnal micro-awakenings linked to genetic risk of Alzheimer's disease

What if certain signs of the disease were to manifest themselves subtly during sleep, long before the first memory problems appear? This is the line of inquiry being explored by a team of researchers at ULiège, with the support of the Stop Alzheimer's Foundation.

11 Aug 2026

New computational tool identifies hidden genes driving asthma

Researchers at Columbia University Mailman School of Public Health, in collaboration with investigators at the University of Chicago, have developed a new computational framework that helps scientists identify genes that play central roles in diseases such as asthma but are often overlooked by existing genetic analysis methods.

11 Aug 2026

Scientists identify parasite-specific protein linked to chronic Toxoplasma infections

Toxoplasma gondii, or Toxoplasma, is a parasite that infects hundreds of millions of people around the world.

11 Aug 2026

Comprehensive brain cell map opens new avenues for Alzheimer's therapies

The brain's immune cells are increasingly recognized as key players in Alzheimer's disease, but exactly how they change as the disease develops has remained unclear.

11 Aug 2026

One cognitive ability stood out in a study of Western diets and Alzheimer’s risk genes

A Western dietary pattern was associated with faster attention decline among older adults carrying the APOE ε4 allele, while no significant cognitive associations emerged for a Prudent dietary pattern. However, the Western diet association lost statistical significance after excluding participants with possible baseline cognitive impairment, making the finding exploratory.

11 Aug 2026

Early-life stress rewires brain epigenetics to heighten sensitivity to future stress

. Early-life stress increased SETD7 and H3K4me1 in the ventral tegmental area of mice, creating an epigenetically primed state that heightened later transcriptional, neuronal, and behavioral responses to stress. Reducing Setd7 during development lowered H3K4me1 and weakened these stress-sensitizing effects, identifying a mechanism that may help explain how early adversity leaves lasting biological effects.

11 Aug 2026

Study uses alternative splicing data to predict protein function

A single human gene can produce multiple protein isoforms through alternative splicing, greatly expanding the functional diversity of the proteome.

10 Aug 2026

Study links delayed Ewing sarcoma growth to reduced Trk and IGF1R pathway markers

A new research paper was published in Volume 17 of Oncotarget on August 7, 2026, titled "Delayed growth of SK-ES-1 Ewing sarcoma tumor xenografts is associated with reduced Trk and IGF1R pathway markers."

10 Aug 2026

New gene signature predicts immunotherapy success for bone marrow cancers

A team led by researchers from the German Cancer Research Center (DKFZ), the HI-STEM Stem Cell Institute, and Medical Clinic V at Heidelberg University Hospital (UKHD) has characterized T cells in the bone marrow in cases of multiple myeloma and acute myeloid leukemia: A specific group of tumor-reactive T cells can recognize and, in principle, fight cancer cells, but is often not sufficiently activated.

10 Aug 2026