Metabolic Disease News and Research

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Fat cells trigger liver stress through secreted lipids

The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins.

2 Apr 2025

Rare sugars curb appetite and mimic diabetes drugs in mice

Rare sugars like D-allulose, D-tagatose, and D-sorbose significantly boosted GLP-1 secretion and suppressed food intake in mice. D-allose also reduced food intake through a unique, GLP-1-independent pathway.

1 Apr 2025

Ibuprofen suppresses sweet taste perception

Researchers explore how taste receptors react to sweet stimuli following exposure to ibuprofen.

31 Mar 2025

Unveiling leptin signaling in the DMH for metabolic effects

Scientists at Pennington Biomedical Research Center have gained greater clarity in the brain regions and neurons that control metabolism, body temperature and energy use.

27 Mar 2025

Anti-inflammatory drugs may reduce metabolic disease risk by inhibiting the sweet taste receptor

Past studies have shown that the human sweet taste receptor conveys sweet perception in the mouth and may help regulate glucose metabolism throughout the body.

25 Mar 2025

Yale scientists develop advanced CRISPR tool to study complex genetic interactions

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases.

20 Mar 2025

Nwd1 gene linked to liver dysfunction in metabolic disease

Metabolic dysfunction-associated steatohepatitis (MASH) is a liver disease that progresses without symptoms and is associated with significant global public health concerns.

11 Mar 2025

Exploring the use of AI for precision hypertension management in diabetes care

Pennington Biomedical Research Center's Dr. Yun Shen will lead a team to explore the use of AI for precision hypertension management in Type-2 diabetes care.

10 Mar 2025

Surgery first strategy could lead to better weight loss outcomes

Mass General Brigham researchers found that total weight loss did not increase for patients who took semaglutide before having weight loss surgery, suggesting that a surgery first strategy could lead to better outcomes.

5 Mar 2025

Melatonin protects skeletal muscle from damage caused by "diabesity"

An international study led by the University of Granada (UGR) has revealed that melatonin, known for its ability to regulate the sleep/wake cycle, can restore the composition of muscle fibers and protect skeletal muscle from damage caused by obesity and type 2 diabetes, known as "diabesity".

5 Mar 2025

Surprising study reveals dads’ weight and diet don’t impact baby’s size

A study shows paternal health factors like BMI and diet do not influence birth weight or length, emphasizing maternal diet's critical role in pregnancy.

4 Mar 2025

The Future of CBD research, marketing, and regulation

In this interview, Professor Ted Dinan, Medical Director at Atlantia Clinical Trials, and Asa Waldstein, Principal at Supplement Advisory Group, discuss Atlantia’s expertise in clinical trials for CBD.