Organoids News and Research

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Organoids are three-dimensional cell cultures from embryonic stem cells or induced pluripotent stem cells that model important features of whole organs.

Newly identified gene drives development of the second most common type of lung carcinoma

A team led by researchers at NYU Langone Health's Perlmutter Cancer Center has identified a gene that drives development of the second most common type of lung carcinoma, offering greater insight into how the disease might someday be treated.

9 Jan 2023

Sugar appears to play a role in polycystic kidney disease, study finds

A study of kidney organoids in a novel lab environment might have downstream implications for the treatment of polycystic kidney disease (PKD), an incurable condition that affects more than 12 million people worldwide.

5 Jan 2023

Scientists pinpoint the routes taken by SARS-CoV-2 to enter and exit cells in our nasal cavity

Somebody just coughed on you. On a plane. At a dinner party. In a supermarket line. If only there were a "morning after" nasal spray that could knock out respiratory viruses' ability to colonize your nose and throat.

5 Jan 2023

Researchers develop a new approach to better understand the biology of polycystic kidney disease

A research team supported by the National Institutes of Health has developed a new approach to better understand the biology of polycystic kidney disease (PKD), an often-life-threatening genetic disorder that affects millions worldwide.

5 Jan 2023

Research shows re-formation of synaptic connectivity in dissociated retinal organoids

Retinal cells grown from stem cells can reach out and connect with neighbors, according to a new study, completing a "handshake" that may show the cells are ready for trials in humans with degenerative eye disorders.

4 Jan 2023

Technical advances expand the application of mass spectrometry imaging in pharmaceutical research

Announcing a new publication for Acta Materia Medica journal. Mass spectrometry imaging (MSI) has been shown to be a valuable tool through nearly every stage of the preclinical drug research and development (R&D) pipeline, and even to the early phase of clinical pharmaceutical evaluation.

3 Jan 2023

Human cortical organoids implanted in mice establish functional connectivity and respond to sensory stimuli

A team of engineers and neuroscientists has demonstrated for the first time that human brain organoids implanted in mice have established functional connectivity to the animals' cortex and responded to external sensory stimuli.

29 Dec 2022

Cellular models based on reprogrammed human cells could boost development of efficient therapies

Studies on diseases that affect the human brain are usually based on animal models which cannot reproduce the complexity of human neuropathies.

22 Dec 2022

Using 3D patient tumor avatars to guide cancer treatment decisions

At any time, most cancer patients are receiving a treatment that does not significantly benefit them while enduring bodily and financial toxicity.

20 Dec 2022

UQ-led project uses 'brain in a dish' to study effects of the Zika virus

A University of Queensland-led project has used a 'brain in a dish' to study the effects of the Zika virus, taking research a step closer towards developing drugs to combat the infection.

12 Dec 2022

Bioengineered soluble ACE2 for brain protection against SARS-CoV-2 infection

Researchers compared the efficiency of bioengineered soluble ACE-2 concerning brain protection during COVID-19.

12 Dec 2022

What is the association between farnesoid X receptor inhibition and protection against COVID-19?

Researchers assessed the association between farnesoid X receptor (FXR) inhibition and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

9 Dec 2022

New approach enables robust intestinal mini-organs to be grown more easily in the lab

Growing human body parts in the lab is a common trope of horror movies and sci-fi books. But growing miniature organ-like tissues in the lab is already within our reach.

6 Dec 2022

Innovative precision oncology enabled by micro-organospheres derived from patients

The development of an automatic microfluidics droplet platform to rapidly generate patient-derived models of cancer.

6 Dec 2022

Multiomics analysis of kidney metabolism reveals a gatekeeper for viral infections

Our kidney filters 180 liters of blood every day and retains nutrients through a process called 'endocytosis' and through active transport in the kidney cells.

2 Dec 2022

Chemical residue from commercial dishwashers causes gut epithelial barrier damage

Residue from rinse agents is left behind on dishes after they are cleaned in professional-grade dishwashers.

1 Dec 2022

Researchers develop 3D organoid model to advance understanding of gastroesophageal junction cancer

Researchers at Johns Hopkins Medicine say they have created a laboratory-grown three-dimensional "organoid" model that is derived from human tissue and designed to advance understanding about how early stages of cancer develop at the gastroesophageal junction (GEJ) — the point where the digestive system's food tube meets the stomach.

1 Dec 2022

Organoids News and Research

Further Reading

Newly identified gene drives development of the second most common type of lung carcinoma

Sugar appears to play a role in polycystic kidney disease, study finds

Scientists pinpoint the routes taken by SARS-CoV-2 to enter and exit cells in our nasal cavity

Researchers develop a new approach to better understand the biology of polycystic kidney disease

Research shows re-formation of synaptic connectivity in dissociated retinal organoids

Technical advances expand the application of mass spectrometry imaging in pharmaceutical research

Human cortical organoids implanted in mice establish functional connectivity and respond to sensory stimuli

Cellular models based on reprogrammed human cells could boost development of efficient therapies

Using 3D patient tumor avatars to guide cancer treatment decisions

UQ-led project uses 'brain in a dish' to study effects of the Zika virus

Bioengineered soluble ACE2 for brain protection against SARS-CoV-2 infection

What is the association between farnesoid X receptor inhibition and protection against COVID-19?

New approach enables robust intestinal mini-organs to be grown more easily in the lab

Innovative precision oncology enabled by micro-organospheres derived from patients

Multiomics analysis of kidney metabolism reveals a gatekeeper for viral infections

Chemical residue from commercial dishwashers causes gut epithelial barrier damage

Researchers develop 3D organoid model to advance understanding of gastroesophageal junction cancer

Scientists discover new potential mechanism for vision loss

UCSC engineers develop new method to automate the growth of cerebral organoids

The potential of Sofosbuvir against COVID-19 neurological symptoms

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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