Tryptophan News and Research

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Tryptophan is one of the 20 standard amino acids, as well as an essential amino acid in the human diet.

Mucosal IgA fused nanobody as a non-invasive, cost-effective prophylaxis and therapeutic option against major SARS-CoV-2 variants

Researchers from the United States developed an affordable, non-invasive, inhalable prophylactic treatment consisting of immunoglobulin (Ig) A fused nanobodies against the SARS-CoV-2 Omicron variant.

2 Dec 2022

Study implicates gut microbiome health in Parkinson's disease

A new study published in the journal Nature Communications discusses the links between this condition that affects the brain and changes in the gut microbiome that may predate brain changes.

1 Dec 2022

Gut microbiome plays a role in Alzheimer's

In a recent review published in the journal Pharmacological Research, researchers in Brazil investigated the role of gut microbiota in cognition, brain function, behavior, and neurodegenerative disease pathogenesis.

17 Nov 2022

National Institutes of Health funds a five-year, $11 million initiative

The conversations between our bone and muscle change as we age, and both are the weaker for it, Medical College of Georgia scientists say.

17 Nov 2022

COVID-19 and the gut

Researchers summarize current knowledge about underlying mechanisms and potential therapeutic approaches for the effects of COVID-19 on the gut.

26 Oct 2022

How the gut microbiome could affect COVID-19 severity

Researchers review the potential role of the gut microbiome in determining severe COVID-19.

27 Sep 2022

New engineered peptides could prevent the superbug crisis

A recent study reports the development of a synthetic antibacterial peptide PLG0206.

22 Sep 2022

Nutritional approaches targeting gut microbiome could improve brain disorders

A new review published in the Clinical Nutrition and Metabolic Care journal focused on studies that utilized the dietary gut microbiota–target interventions to improve mental health conditions. It also discussed some suggestions for developing more robust and informative interventions for diet–microbiome studies.

15 Sep 2022

Can daytime feeding prevent mood vulnerability in night workers?

A new study explores the effect of daytime feeding on affective disorder incidence in this subset of workers.

15 Sep 2022

MOO can alleviate depression via increasing 5-HTP in the gut microbiota, study reveals

Announcing a new article publication from Acta Pharmaceutica Sinica B. Morinda officinalis oligosaccharides(MOO) is an oral drug approved in China for the treatment of depression in China.

5 Sep 2022

Inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth

Researchers at Sanford Burnham Prebys, led by Ze'ev Ronai, Ph.D., have shown for the first time that inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth.

1 Sep 2022

SARS-CoV-2 mutational spectra based on reconstructed phylogenetic tree

In a new study, researchers assessed the impact of mutagenesis on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome and the effects of mutations in the neutral regions and non-neutral regions of the genome.

25 Aug 2022

What is the association between polyfluoroalkyl substance exposure and risk of non-viral hepatocellular carcinoma?

The current study, published online in the journal JHEP Reports, looks at PFAS, which are endocrine disruptors and potential hepatotoxins.

11 Aug 2022

Nutritive intervention could be an effective treatment method in maintaining human health

In a new study, researchers assessed the impact of dietary regulation on human health and disease.

1 Aug 2022

Scientists explore guanine-specific pocket in SARS-CoV-2 nucleocapsid protein of therapeutic value against multiple coronaviruses

Researchers studied open and closed conformations of the C-terminal of SARS-CoV-2 nucleocapsid (N) protein termed the NCTD.

19 Jul 2022

Mild COVID causes increase in neurotoxic metabolites

In a recent study posted to the bioRxiv* pre-print server, researchers investigated the blood levels of neurotoxic metabolites in patients with mild coronavirus disease 2019 (COVID-19).

23 Jun 2022

Researchers model a complex childhood disease on-a-chip

Millions of children in low- and middle-income nations suffer from environmental enteric dysfunction (EED), a chronic inflammatory disease of the intestine that is the second leading cause of death in children under five years old.

23 Jun 2022

Diet rich in polyphenols can prevent inflammation in the elderly

Polyphenols in the foods that we eat can prevent inflammation in older people, since they alter the intestinal microbiota and induce the production of the indole 3-propionic acid (IPA), a metabolite derived from the degradation of tryptophan due to intestinal bacteria.

8 Jun 2022

Immunogenicity predictions reveal SARS-CoV-2 CD8+ T-cell epitopes

In a recent study posted to the bioRxiv* pre-print server, researchers identified several new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epitopes displayed on human leukocyte antigens class I (HLA-I) molecules.

26 May 2022