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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Study identifies abnormal biomarkers associated with obesity in early elementary-aged Latino youth

In the United States, low-income, Latino youth are disproportionately affected by obesity with 25.8% of Latino youth aged 2-19 considered to have obesity, which is approximately two times more likely when compared to their non-Latino white counterparts.

14 Mar 2023

What is the influence of prenatal second-hand smoke exposure on infant self-regulation?

A new study aimed to analyze an important gap concerning the impact of prenatal SHS exposure on infant self-regulation.

14 Mar 2023

Oral host responses to SARS-CoV-2 predict progression of COVID-19

In a recent study posted to the medRxiv* preprint server, researchers at the University of North Carolina and the National Institutes of Health determined the associations between oral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), oral antibodies against SARS-CoV-2, and coronavirus disease 2019 (COVID-19) symptoms.

14 Mar 2023

SARS-CoV-2 replication persists for weeks in lungs after symptom onset in severe COVID-19

Researchers observe persistent SARS-CoV-2 replication in severe COVID-19 patient lungs.

13 Mar 2023

Mercury and urinary arsenobetaine in blood are strong biomarkers for seafood consumption among pregnant women

Mercury content in RBCs and arsenobetaine in urine could be considered seafood consumption biomarkers during pregnancy.

10 Mar 2023

Review on factors related to variations in human microbiota

In a recent review published in Current Opinion in Microbiology, researchers reviewed existing data on variations in human microbiota, emphasizing on ageing- and ethnicity-associated changes in the microbiota.

8 Mar 2023

Pilot trial tests nasal monoclonal antibody treatment for COVID-19

A pilot trial by investigators from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, tested the nasal administration of the drug Foralumab, an anti-CD3 monoclonal antibody.

8 Mar 2023

Denosumab may benefit postmenopausal patients with hormone receptor-negative breast tumors and RANK protein expression

The drug denosumab is currently used to treat osteoporosis and bone metastases. For more than a decade, its potential therapeutic benefit in the treatment of breast cancer has also been studied.

7 Mar 2023

Tumors' response to hormone therapy may be a biomarker for personalization of breast radiotherapy

How estrogen receptor-positive (ER+) breast cancer responds to hormone therapy may hold keys to understanding how it will respond to radiation therapy, and an experimental drug that increases the effectiveness of hormone therapy also overcomes radiation resistance in breast cancer, a study by UT Southwestern Medical Center researchers shows.

6 Mar 2023

Wrist-worn device can accurately predict troponin-I and obstructed arteries in five minutes

An experimental wrist-worn device was found to predict troponin-I and obstructed arteries with 90% accuracy in five minutes, according to research being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

6 Mar 2023

Therapeutic ketosis for mild cognitive impairment, Alzheimer's and Parkinson's

A new study in Frontiers in Neurology aimed to review the available studies which support the clinical utility of ketogenic interventions in PD, MCI, and AD.

5 Mar 2023

Pitt and UCI researchers secure funding to advance understanding of patient reactions to Alzheimer's diagnoses

University of Pittsburgh and University of California, Irvine (UCI) researchers have received funding from the National Institute of Aging to advance understanding of real-world patient and family member reactions to biomarker-informed Alzheimer's disease and related disorders diagnoses.

3 Mar 2023

Association between cardiovascular disease and transportation noise revealed in new research

Researchers assessed the association between cardiovascular disease and transportation noise.

3 Mar 2023

Astrocytes exhibit stronger acid response with REM sleep in epileptic mice

Researchers at Tohoku University have shown that astrocytes - star-shaped glial cells that control the local ionic and metabotropic environment of the brain - exhibit an acid response with REM sleep in mice.

3 Mar 2023

Study identifies renalase as a novel independent predictor of COVID-19-related mortality

Researchers assessed the role of renalase as an independent predictor of COVID-19-related mortality.

2 Mar 2023

The rapid diagnosis of drug-resistant and drug-sensitive tuberculosis using mass spectrometry and machine learning

In a recent study posted to the Preprints with The Lancet SSRN* server, a team of researchers in China developed a machine learning-based diagnostic tool to detect tuberculosis and drug-resistant tuberculosis using nanoparticle-enhanced laser desorption/ionization mass spectrometry (NPELDI MS) to determine metabolic fingerprints from serum samples.

28 Feb 2023

Mass spectrometry-based identification of COVID-19 biomarkers

In a recent study published in the journal Metabolites, researchers reported that mass spectrometry (MS)-based metabolomic approaches have a high potential for biomarker discovery.

28 Feb 2023

An overview of the anti-inflammatory effects of nuts

Researchers summarize existing literature on the effects of consuming nuts on biomarkers of inflammation and oxidative stress.

28 Feb 2023

Study shows the beneficial effect of verapamil in children with newly-diagnosed type 1 diabetes

Published in JAMA, a University of Minnesota led study shows that verapamil, a drug commonly used to treat high blood pressure and heart conditions, can have a beneficial effect on the pancreas in children with newly-diagnosed type 1 diabetes (T1D).

24 Feb 2023

The relationship between DNAm-based age acceleration measures in the prediction of cross-sectional and longitudinal health outcomes and mortality

Researchers assessed the association between deoxyribonucleic acid methylation (DNAm)-based clocks or aging measures and demographic and serological parameters in estimating health-associated outcomes, including deaths.

24 Feb 2023

Biomarker News and Research

Further Reading

Study identifies abnormal biomarkers associated with obesity in early elementary-aged Latino youth

What is the influence of prenatal second-hand smoke exposure on infant self-regulation?

Oral host responses to SARS-CoV-2 predict progression of COVID-19

SARS-CoV-2 replication persists for weeks in lungs after symptom onset in severe COVID-19

Mercury and urinary arsenobetaine in blood are strong biomarkers for seafood consumption among pregnant women

Review on factors related to variations in human microbiota

Pilot trial tests nasal monoclonal antibody treatment for COVID-19

Denosumab may benefit postmenopausal patients with hormone receptor-negative breast tumors and RANK protein expression

Tumors' response to hormone therapy may be a biomarker for personalization of breast radiotherapy

Wrist-worn device can accurately predict troponin-I and obstructed arteries in five minutes

Therapeutic ketosis for mild cognitive impairment, Alzheimer's and Parkinson's

Pitt and UCI researchers secure funding to advance understanding of patient reactions to Alzheimer's diagnoses

Association between cardiovascular disease and transportation noise revealed in new research

Astrocytes exhibit stronger acid response with REM sleep in epileptic mice

Study identifies renalase as a novel independent predictor of COVID-19-related mortality

The rapid diagnosis of drug-resistant and drug-sensitive tuberculosis using mass spectrometry and machine learning

Mass spectrometry-based identification of COVID-19 biomarkers

An overview of the anti-inflammatory effects of nuts

Study shows the beneficial effect of verapamil in children with newly-diagnosed type 1 diabetes

The relationship between DNAm-based age acceleration measures in the prediction of cross-sectional and longitudinal health outcomes and mortality

Event guide: 15th World Clinical Biomarkers & CDx Europe eBook

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