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Scientists identify novel antibodies for fighting malaria

A novel class of antibodies that binds to a previously untargeted portion of the malaria parasite could lead to new prevention methods, according to a study from researchers at the National Institutes of Health (NIH) published today in Science.

3 Jan 2025

Researchers grow tumor organoids from blood to tackle breast cancer metastasis

Tumor cells circulating in the blood are the "germ cells" of breast cancer metastases. They are very rare and could not be propagated in the culture dish until now, which made research into therapy resistance difficult.

3 Jan 2025

New Year, new approach to weight loss: Almost three quarters of UK women are considering using GLP-1s in 2025

As 2024 draws to a close, the new year ushers in the opportunity to set new goals for the year ahead. While weight-loss and fitness are staples of New Year resolutions they are commonly known to be the unsustainable resolutions that don't continue past January.

3 Jan 2025

Polarimetry tracks Achilles tendon regeneration

Achilles tendon injuries are common but challenging to monitor during recovery due to the limitations of current imaging techniques. Researchers, led by Associate Professor Zeng Nan from the International Graduate School at Shenzhen, Tsinghua University, have applied Mueller matrix polarimetry, a non-invasive imaging method, to more accurately observe and evaluate the healing of Achilles tendon injuries.

2 Jan 2025

New immunotherapy shows long-term benefits in preventing squamous cell carcinoma

A new study by investigators from Mass General Brigham uncovers how a novel immunotherapy prevents squamous cell carcinoma, with benefits lasting five years after treatment.

2 Jan 2025

Breakthrough in immunology: AbMAP’s novel approach to antibody modeling

Researchers developed AbMAP, a cutting-edge framework leveraging transfer learning to model antibody hypervariable regions, significantly improving design and immune repertoire analysis.

2 Jan 2025

Insilico Medicine nominates ISM1745 as preclinical candidate for MTAP-deleted cancers

Insilico Medicine ('Insilico'), a clinical-stage generative artificial intelligence (AI)-driven drug discovery and development company, today announced the nomination of ISM1745, a potentially best-in-class MTA cooperative PRMT5 inhibitor with AI-powered novel scaffold, as preclinical candidate (PCC) for the treatment of MTAP-deleted cancers.

2 Jan 2025

New research affirms clozapine safety with minimal blood cancer risk

An inter-departmental research team at the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) has conducted the world's first analytic real-world cohort study on the association of clozapine, a highly efficacious antipsychotic drug, with the incidence of blood cancer.

2 Jan 2025

Skin explants reveal how Ebola virus moves through the body

Ebola is a deadly hemorrhagic disease caused by a virus that is endemic in parts of East-Central and West Africa. Most people are aware that a primary route for person-to-person transmission is through contact with bodily fluids from an infected person.

1 Jan 2025

Nonpharmacologic pain intervention provides benefits to people with dialysis-dependent kidney failure

Among people with dialysis-dependent kidney failure, a form of psychological therapy called pain coping skills training reduced how much pain got in the way of their daily lives, also known as pain interference.

30 Dec 2024

Emergence of FC428 clone and the global spread of ceftriaxone-resistant gonorrhea

Neisseria gonorrhoeae, responsible for the sexually transmitted infection gonorrhea, is becoming increasingly difficult to treat as the pathogen has developed resistance to multiple antibiotics.

30 Dec 2024

The science behind phytosome formation and its therapeutic potential

Announcing a new publication for Acta Materia Medica journal. Phytosomes, a novel drug delivery system, have recently attracted substantial attention, because of their exceptional ability to increase the therapeutic efficacy and bioavailability of phytoconstituents.

30 Dec 2024

Laser-textured stents offer promising solution for vascular diseases

The research team led by Dr. Hojeong Jeon and Dr. Hyung-Seop Han of the Biomaterials Research Center at the Korea Institute of Science and Technology (KIST, President Oh Sang-Rok), along with Dr. Indong Jun from KIST Europe, has developed a novel stent surface treatment technology using laser patterning.

26 Dec 2024