Enzyme News and Research

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Drug-metabolizing enzyme may be a major player in safety concerns related to the painkiller diclofenac

Safety concerns related to the widely used painkiller diclofenac may be tied to a little-studied drug-metabolizing enzyme whose expression can vary as much as 3,000 times from one individual to the next, according to new research.

24 Apr 2023

Researchers discover a key player in preventing 'insulin shock'

Just over a century has passed since the discovery of insulin, a time period during which the therapeutic powers of the hormone have broadened and refined. Insulin is an essential treatment for type 1 diabetes and often for type 2 diabetes, as well.

24 Apr 2023

Novel self-amplifying RNA vaccine confers durable protection against COVID-19, reduces viral shedding in primate study

A self-amplifying replicon RNA vaccine against SARS-CoV-2 can elicit durable and protective immunity in pigtail macaques, even after neutralizing antibody responses have waned to undetectable levels.

23 Apr 2023

New sensing platform for detecting biological markers related to cancers

When doctors are examining suspected cancer cases, they turn to biomarker tests to help make a diagnosis.

21 Apr 2023

Research reveals a more effective treatment for multiple sclerosis patients

Degeneration of myelin, an insulating sheath required for rapid communication between nerve cells, and neuroinflammation are notable hallmarks of Multiple Sclerosis (MS) and related neurodegenerative disorders such as Alzheimer's disease or Huntington's disease that affect roughly 2.8 million people in the world.

21 Apr 2023

A downstream pathway critical for lymphoma development discovered

MYC proteins are important regulators of cancer cell growth, proliferation and metabolism through their ability to increase the expression of proteins involved in these processes.

20 Apr 2023

Study should spur the development of alternative range of anti-TB inhibitors

Tuberculosis (TB) is one of the deadliest infectious diseases worldwide that is spread in the air like the common cold. TB is caused by the bacterium Mycobacterium tuberculosis (Mtb) and was responsible for approximately 1.6 million deaths in 2021.

20 Apr 2023

Protective mucosal and systemic immunity provided by a single-dose novel live-attenuated intranasal SARS-CoV-2 vaccine candidate

Researchers explored the protective systemic and mucosal immunity provided by a single dose of a live-attenuated SARS-CoV-2 vaccine candidate.

20 Apr 2023

Protein OCLN found to play crucial role in SARS-CoV-2 cell-to-cell transmission

Research explains how the SARS-CoV-2 virus spreads efficiently by directly infecting neighboring cells through a process called cell-to-cell transmission. The virus uses a protein called occludin (OCLN) to enter the cells and causes syncytium formation, which leads to viral spread.

20 Apr 2023

Gene therapy approach can decrease intraocular pressure in pre-clinical models of glaucoma

Scientists at Trinity College Dublin today announced a significant development towards a new therapeutic treatment of glaucoma.

19 Apr 2023

Discovery offers a potential target for TB therapies

In ongoing research aimed at developing more effective treatments for tuberculosis (TB), University of Massachusetts Amherst microbiologists have identified a long-sought gene that plays a critical role in the growth and survival of the TB pathogen.

19 Apr 2023

New biologic inactivates potent opioid and reverses overdose

A new therapeutic designed by Scripps Research chemists can alter the molecular structure of the potent opioid carfentanil, inactivating the opioid and reversing a carfentanil overdose.

18 Apr 2023

Novel assay based on hybrid DNA-RNA probe for detecting food contaminated with salmonella

A team of researchers have developed an easy-to-use colorimetric assay for the detection of food contaminated with salmonella.

18 Apr 2023

Unravelling the factors influencing host tropism of SARS-CoV-2-related bat coronaviruses

Researchers investigated the tropism of SC2r-CoVs infecting Rhinolophus bats.

18 Apr 2023

Consuming mangos boosts gut microbiome diversity: Benefits for overweight and obese individuals

In a recent study published in the journal Food Science and Nutrition, researchers at San Diego State University investigated how consuming fresh mango affects gut health and microbiome.

17 Apr 2023

Understanding the prevalence and dissemination aminoglycoside resistance genes

Choosing the appropriate antibiotics to treat bacterial infections has grown more challenging because of the emergence of antibiotic-resistant bacteria.

17 Apr 2023

New discovery can revolutionize the diagnosis and treatment of Alzheimer's disease

Recently, a team of South Korean scientists led by Director C. Justin LEE of the Center for Cognition and Sociality within the Institute for Basic Science made a new discovery that can revolutionize both the diagnosis and treatment of Alzheimer's Disease.

17 Apr 2023

Enzyme News and Research

Drug-metabolizing enzyme may be a major player in safety concerns related to the painkiller diclofenac

Researchers discover a key player in preventing 'insulin shock'

Novel self-amplifying RNA vaccine confers durable protection against COVID-19, reduces viral shedding in primate study

New sensing platform for detecting biological markers related to cancers

Research reveals a more effective treatment for multiple sclerosis patients

A downstream pathway critical for lymphoma development discovered

Study should spur the development of alternative range of anti-TB inhibitors

Protective mucosal and systemic immunity provided by a single-dose novel live-attenuated intranasal SARS-CoV-2 vaccine candidate

Protein OCLN found to play crucial role in SARS-CoV-2 cell-to-cell transmission

Gene therapy approach can decrease intraocular pressure in pre-clinical models of glaucoma

Discovery offers a potential target for TB therapies

New biologic inactivates potent opioid and reverses overdose

Novel assay based on hybrid DNA-RNA probe for detecting food contaminated with salmonella

Unravelling the factors influencing host tropism of SARS-CoV-2-related bat coronaviruses

Consuming mangos boosts gut microbiome diversity: Benefits for overweight and obese individuals

Understanding the prevalence and dissemination aminoglycoside resistance genes

New discovery can revolutionize the diagnosis and treatment of Alzheimer's disease

Is there an association between COVID-19 and the risk of developing an autoimmune disease?

New PET imaging breakthrough offers potential Alzheimer's diagnosis and treatment breakthrough

Study develops a novel intranasal influenza virus-vectored vaccine for SARS-CoV-2

Understanding the DNA Damage Response in Innate Immunity eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo