Proliferation News and Research

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New screening platform can be used to discover more effective drugs for type 1 diabetes

With nearly 2 million Americans battling type 1 diabetes, it is no surprise that clinical therapies for the disease are constantly evolving and improving.

16 Dec 2020

Study explores link between aging, obesity, and metabolic diseases

Unraveling the links among obesity, aging, telomere lengths and metabolic diseases is the subject of the study published today in Nature Metabolism by a collaborative research team at The University of Texas Health Science Center at Houston (UTHealth).

14 Dec 2020

Emergence of resistant SARS-CoV-2 variant in immunocompromised patient following therapeutic antibody use

The focus is increasingly moving towards vaccine roll-out as the world faces the real possibility of the second year of social and economic restrictions.

14 Dec 2020

Study identifies protein as potential therapeutic target for leishmaniasis vaccines

According to the results of research led by the Complutense University of Madrid (UCM), one the various strategies deployed by the Leishmania parasite to avoid triggering the human immune system is to activate the SHP-1 protein.

11 Dec 2020

High expression of VRK1 protein can reduce survival in neuroblastoma patients

Researchers from the Departments of Cell Biology and Medical Physiology at the University of Seville have identified that a high expression of the human protein VRK1 is associated with tumour aggressiveness and low survival among neuroblastoma patients.

11 Dec 2020

Reverse phenotyping shows reactive T cell profiles in SARS-CoV-2 infection

A new study appearing as a preprint on the medRxiv* browser in December 2020 employs reverse phenotyping technology to explore T cell responses in COVID-19.

10 Dec 2020

Research presents potential therapeutic strategy for reducing age-related diseases

Research findings by a KAIST team provide insight into the complex mechanism of cellular senescence and present a potential therapeutic strategy for reducing age-related diseases associated with the accumulation of senescent cells.

10 Dec 2020

UVA researchers identify genes that influence risk for common form of heart disease

Researchers at the University of Virginia have shed light on how our genes affect our risk for coronary artery disease, the most common form of heart disease.

10 Dec 2020

New data shows abemaciclib continues to benefit high-risk, HR+, HER2-, early-stage breast cancer patients

Extended follow-up data from the phase III monarchE trial showed that adding the cyclin-dependent kinase (CDK) inhibitor abemaciclib (Verzenio) to standard adjuvant endocrine therapy continued to improve invasive disease-free survival (IDFS) among patients with high-risk, node-positive, early-stage, HR-positive, HER2-negative breast cancer, according to data presented at the 2020 San Antonio Breast Cancer Symposium, held Dec. 8-11.

9 Dec 2020

FASLG gene may drive cytokine-linked adverse COVID-19 outcomes with age

A new study published on the preprint server bioRxiv in December 2020 reveals the role played by certain genetic factors in this group, in particular the FASLG gene belonging to the tumor necrosis factor (TNF) family.

8 Dec 2020

Study findings can guide personalized breast cancer therapies based on melatonin

A Brazilian study published in the Journal of Pineal Research describes a group of genes potentially regulated by the hormone melatonin in some types of cancer, especially breast cancer.

8 Dec 2020

Research team develops a new decoding method for viral genes

Comprehensive identification of viral proteins encoded by viral genes is required to understand the pathophysiology of viral infections.

7 Dec 2020

Xylitol and grapefruit seed extract shows promise in preventing SARS-CoV-2 infection, study finds

A team of researchers at the Feinberg School of Medicine demonstrated that xylitol and grapefruit seed extract (GSE) could prevent SARS-CoV-2 infection. These can be used as a nasal spray to contain the spread of the coronavirus.

7 Dec 2020

Novel modular design approach to antibody nanocage generation

A new study shows the benefits of using computational design to create antibody nanocages that have the required orientation.

7 Dec 2020

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Clinical investigators from Hackensack Meridian Health John Theurer Cancer Center (JTCC), a member of the Georgetown Lombardi Comprehensive Cancer Center consortium, are to present updates on treatment advances in multiple myeloma (MM), mantle cell lymphoma (MCL), and other types of B-cell lymphoma (BCL) as well as leukemia at the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, to be held virtually from December 5-8, 2020.

7 Dec 2020

Study provides mechanistic insights about the role of neutrophils in psoriasis pathogenesis

Psoriasis has always been a common disease. Historically, its causes were obscure and surrounded by stigma; it wasn't until recently that scientists categorized it as an autoimmune condition.

4 Dec 2020

Researchers create first map of microbiome of dental black plaque in adults

The dark pigmentations that appear around the gums on dental enamel have a bacterial origin and there is currently no definitive therapy to remove it entirely.

3 Dec 2020

SARS-CoV-2 enters the CNS via multiple routes and causes various neurological disorders

The COVID-19 pandemic has led to millions of deaths across the globe. The causative agent of this disease is the novel coronavirus, SARS-CoV-2.

3 Dec 2020

The vaginal microbiome may impact the efficacy of HIV prevention therapy

A new study has revealed that vaginal microbial communities are linked with an increased risk of HIV acquisition and may also impact the efficacy of PrEP.

3 Dec 2020

Scientists report the first map of molecular responses of human lung cells to SARS-CoV-2 infection

In a multi-group collaborative involving the National Emerging Infectious Disease Laboratories (NEIDL), the Center for Regenerative Medicine (CReM), and the Center for Network Systems Biology (CNSB), scientists have reported the first map of the molecular responses of human lung cells to infection by SARS-CoV-2.

2 Dec 2020

Proliferation News and Research

New screening platform can be used to discover more effective drugs for type 1 diabetes

Study explores link between aging, obesity, and metabolic diseases

Emergence of resistant SARS-CoV-2 variant in immunocompromised patient following therapeutic antibody use

Study identifies protein as potential therapeutic target for leishmaniasis vaccines

High expression of VRK1 protein can reduce survival in neuroblastoma patients

Reverse phenotyping shows reactive T cell profiles in SARS-CoV-2 infection

Research presents potential therapeutic strategy for reducing age-related diseases

UVA researchers identify genes that influence risk for common form of heart disease

New data shows abemaciclib continues to benefit high-risk, HR+, HER2-, early-stage breast cancer patients

FASLG gene may drive cytokine-linked adverse COVID-19 outcomes with age

Study findings can guide personalized breast cancer therapies based on melatonin

Research team develops a new decoding method for viral genes

Xylitol and grapefruit seed extract shows promise in preventing SARS-CoV-2 infection, study finds

Novel modular design approach to antibody nanocage generation

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Study provides mechanistic insights about the role of neutrophils in psoriasis pathogenesis

Researchers create first map of microbiome of dental black plaque in adults

SARS-CoV-2 enters the CNS via multiple routes and causes various neurological disorders

The vaginal microbiome may impact the efficacy of HIV prevention therapy

Scientists report the first map of molecular responses of human lung cells to SARS-CoV-2 infection

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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