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Celiac disease may now be curable with biodegradable nanoparticles

A phase 2 trial just concluded shows that people with celiac disease may now be able to hope for a cure, through a treatment that makes the immune system tolerant towards gluten. This could eventually make it possible for such individuals to eat gluten-containing foods without fear.

22 Oct 2019

More brain pathology and hospitalizations associated with faster rate of cognitive decline

Older people who experienced more hospitalizations and also had more Alzheimer's pathology in their brain experienced the fastest rates of cognitive decline, according to study results published in the October 15 online issue of the Annals of Neurology.

22 Oct 2019

New study identifies gene that causes intellectual disability syndrome

It used to take several years or sometimes decades to unequivocally identify the genes that cause rare human syndromes that affect very few individuals. Nowadays, however, human geneticists and fly and mouse biologists have the means to work together to integrate their data, which has significantly accelerated the pace of disease and gene discovery.

22 Oct 2019

Q-Suite Motor Assessment Tool helps detect subtle motor abnormalities in children

In clinical trials of adults with Huntington's disease (HD) the Q-Suite Motor Assessment Tool (Q-Motor) has proven to be helpful to detect and quantitate subtle motor abnormalities.

22 Oct 2019

E. coli bacteria study may provide clues about drug resistance

Swapping a single amino acid in a simple bacterial protein changes its structure and function, revealing the effects of complex gene evolution, finds a new study published in the journal eLife.

22 Oct 2019

USC study shows how tumor cells circulating in the blood target distant organs

Most cancers kill because tumor cells spread beyond the primary site to invade other organs. Now, a USC study of brain-invading breast cancer cells circulating in the blood reveals they have a molecular signature indicating specific organ preferences.

22 Oct 2019

LSU Health New Orleans awarded $1.74 million to advance research on Usher syndrome

Jennifer J. Lentz, PhD, Associate Professor at LSU Health New Orleans Neuroscience Center of Excellence and Departments of Otorhinolaryngology, Genetics and Ophthalmology, in collaboration with Robert K. Koenekoop MD, PhD and Professor of Pediatric Surgery, Human Genetics and Ophthalmology at McGill University in Montreal, Quebec, Canada, has been awarded a $1.74 million USD grant to advance research on Usher syndrome.

22 Oct 2019

Researchers elucidate properties of blood factor involved in weight loss and aging

Aging is a process that affects all functions of the human body, particularly brain function. However, aging can be delayed through lifestyle changes (physical exercise, restricting calorie intake, etc.).

22 Oct 2019

Taste neurons could be controlling feeding behaviour find researchers

Researchers from the University of California, Riverside used a common fruit fly (Drosophila melanogaster) to find the association between taste neurons and control of feeding behaviours. They noted that if they genetically modulated these flies, they could make them selectively avoid certain chemicals including acids, bitter compounds, salty substances etc. The results of their study appeared in the October issue of the journal Cell Reports.

22 Oct 2019

High glucose impairs circadian clock function, may increase cardiovascular risk

High glucose in obesity appears to gum up the works of the circadian clocks inside our cells that help regulate the timing of many body functions across the 24-hour day and drive the risk of cardiovascular disease, scientists say.

22 Oct 2019

New treatment shows promise to reverse celiac disease

Results of a new phase 2 clinical trial using technology developed at Northwestern Medicine show it is possible to induce immune tolerance to gluten in individuals with celiac disease. The findings may pave the way for treated celiac patients to eventually tolerate gluten in their diet.

22 Oct 2019

Healthiest gut bacteria with plant-based or Mediterranean diet

A new study shows that specific foods that are supplied by either a plant-based or a Mediterranean-type diet can protect the gut against inflammatory disorders, by selectively promoting the growth of anti-inflammatory bacteria.

21 Oct 2019

Creatine powers fight against cancer, improves efficacy of immunotherapies

The immune system functions as the body’s defense against pathogens and harmful substances, including cancer cells. They protect the body against potential harm. In cases of cancer, though the body tries to fight the tumor cells, they may become too aggressive for the immune system to eradicate.

21 Oct 2019

Cantabio, LIH jointly investigate DJ-1 targeting compounds in immune associated diseases

DJ-1 is well known as an important target for the treatment of a number of diseases such as Parkinson's disease. Cantabio has been developing novel small molecule therapeutic program targeting the DJ-1 protein with a focus on Parkinson's and also exploring a number of other disease areas.

21 Oct 2019

Columbia researchers capture new detailed images of a temperature-sensing molecule

Columbia University researchers have captured new detailed images of a temperature-sensing molecule in its open, intermediate, and closed states.

21 Oct 2019

Researchers use mouse model to better understand mechanism involved in atrial fibrillation

Atrial fibrillation is the most common heart arrhythmia in humans. This condition increases the risk of heart failure, stroke, dementia and death, and current treatments have suboptimal efficacy and carry side effects.

21 Oct 2019

Discovery about DNA-reeling bacteria can help inform strategies to stop bacterial infection

A new study from Indiana University has revealed a previously unknown role a protein plays in helping bacteria reel in DNA in their environment -- like a fisherman pulling up a catch from the ocean.

21 Oct 2019

Pluripotent stem cells help advance understanding of how Huntington's disease develops

Huntington's disease (HD) is a fatal hereditary disease for which there is no cure. A novel study from Cedars-Sinai Medical Center, Los Angeles, using pluripotent stem cells advances understanding of how the disease develops and may help pave the way for identifying pathways for future treatments.

21 Oct 2019

Haptoglobin binds hemoglobin that causes brain damage after cerebral hemorrhage

Patients who survive a cerebral hemorrhage may suffer delayed severe brain damage caused by free hemoglobin, which comes from red blood cells and damages neurons. Researchers at the University of Zurich and the UniversityHospital Zurich have now discovered a protective protein in the body called haptoglobin, which prevents this effect.

21 Oct 2019

New method may offer effective treatment for pancreatic cancer with fewer side effects

Pancreatic cancer is one of the leading causes of cancer-related deaths worldwide. Patients with pancreatic cancer often receive chemotherapy or radiation therapy, which are not always effective and can have toxic side effects.

21 Oct 2019

Protein C News and Research

Celiac disease may now be curable with biodegradable nanoparticles

More brain pathology and hospitalizations associated with faster rate of cognitive decline

New study identifies gene that causes intellectual disability syndrome

Q-Suite Motor Assessment Tool helps detect subtle motor abnormalities in children

E. coli bacteria study may provide clues about drug resistance

USC study shows how tumor cells circulating in the blood target distant organs

LSU Health New Orleans awarded $1.74 million to advance research on Usher syndrome

Researchers elucidate properties of blood factor involved in weight loss and aging

Taste neurons could be controlling feeding behaviour find researchers

High glucose impairs circadian clock function, may increase cardiovascular risk

New treatment shows promise to reverse celiac disease

Healthiest gut bacteria with plant-based or Mediterranean diet

Creatine powers fight against cancer, improves efficacy of immunotherapies

Cantabio, LIH jointly investigate DJ-1 targeting compounds in immune associated diseases

Columbia researchers capture new detailed images of a temperature-sensing molecule

Researchers use mouse model to better understand mechanism involved in atrial fibrillation

Discovery about DNA-reeling bacteria can help inform strategies to stop bacterial infection

Pluripotent stem cells help advance understanding of how Huntington's disease develops

Haptoglobin binds hemoglobin that causes brain damage after cerebral hemorrhage

New method may offer effective treatment for pancreatic cancer with fewer side effects

Industry Focus eBook - Cell biology (5th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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